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Killer in Biological News

Scientists link immune system's natural killer cells to infant liver disease

CINCINNATI Scientists have linked an overactive response by one of the immune system's key weapons against infection natural killer, or NK, cells to the onset of biliary atresia in infants, a disease where blocked bile ducts can cause severe liver damage and death. Researchers at Cincinnati ...

Termite killer lingers as a potent greenhouse gas

Sulfuryl fluoride (SO 2 F 2 ), a gas commonly used to rid buildings of termites and other pests, is a greenhouse gas that remains in the atmosphere about 36 years, six to 10 times longer than previously thought, according to a research team led by Jens Mhle, an atmospheric chemist at Scripps Insti...

Frog's immune system is key in fight against killer virus

Scientists from Queen Mary, University of London have discovered how changes to a frog's immune system may be the key to beating a viral infection which is devastating frog populations across the UK. Communities of common frogs (Rana temporaria) are being struck down by a foreign virus which i...

Shades of 1918? New study compares avian flu with a notorious killer from the past

In the waning months of the First World War, a lethal virus known as the Spanish flu (influenza A, subtype H1N1), swept the United States, Europe and Asia in three convulsive waves. The year was 1918. The ensuing pandemic claimed up to 100 million victims, most of whom succumbed to severe respirat...

Older killer whales make the best mothers

Killer whales ( Orcinus orca ) nearing the menopause may be more successful in rearing their young. New research published in BioMed Central's open access journal Frontiers in Zoology shows that estimated survival rates for calves born to these older mothers were 10% higher than those for other ...

Brown chemist finds gray mold's killer gene

PROVIDENCE, R.I. [Brown University] Gray mold is a gardener's nightmare. The fungus, also known by its scientific name Botrytis cinerea , is a scourge to more than 200 agricultural and ornamental plant species, including staples such as tomatoes, strawberries, snap and lima beans, cabbage, lettu...

Wistar scientists find key to keeping killer T cells in prime shape for fighting infection, cancer

Like tuning a violin to produce strong, elegant notes, researchers at The Wistar Institute have found multiple receptors on the outside of the body's killer immune system cells which they believe can be selectively targeted to keep the cells in superb infection- and disease-fighting condition. ...

Ancient protein offers clues to killer condition

More than 600 million years of evolution has taken two unlikely distant cousins turkeys and scallops - down very different physical paths from a common ancestor. But University of Leeds researchers have found that a motor protein, myosin 2, remains structurally identical in both creatures. T...

Early exposure to common weed killer impairs amphibian development

MEDFORD/SOMERVILLE, Mass. - Tadpoles develop deformed hearts and impaired kidneys and digestive systems when exposed to the widely used herbicide atrazine in their early stages of life, according to research by Tufts University biologists. The results present a more comprehensive picture of how...

Chemistry turns killer gas into potential cure

Despite its deadly reputation, the gas carbon monoxide (CO) could actually save lives and boost health in future as a result of leading-edge UK research. Chemists at the University of Sheffield have discovered an innovative way of using targeted small doses of CO which could benefit patients wh...

New hope for horse lovers as effective control for killer ragwort is proposed

Scientists propose developing an environmentally-friendly fungal spray that would specifically target Ragwort, infecting and killing the weed at a critical growth stage. This spray will contain a host-specific, plant pathogenic fungus as the active ingredient and will have no side-effects on non-...

Cancer cell 'bodyguard' turned into killer

CORVALLIS, Ore. If you're a cancer cell, you want a protein called Bcl-2 on your side because it decides if you live or die. It's usually a trusted bodyguard, protecting cancer cells from programmed death and allowing them to grow and form tumors. But sometimes it turns into their assassin. S...

Scripps Oceanography Research pegs ID of red tide killer

Researchers at Scripps Institution of Oceanography at UC San Diego have identified a potential red tide killer. Red tides and related phenomena in which microscopic algae accumulate rapidly in dense concentrations have been on the rise in recent years, causing hundreds of millions of dollars in wo...

Revealed -- Mosquito genes that could be controlling the spread of killer viruses

The genes that make up the immune system of the Aedes aegypti mosquito which transmits deadly viral diseases to humans have been identified in new research out today in Science. The immune system of this mosquito is of great importance as scientists believe it plays a key role in controlling the...

Increase in drug development for killer diseases is not enough

A recent report shows that drug development for killer diseases such as HIV/AIDS, TB, Malaria, Chagas and Sleeping Sickness has increased in recent years. This is despite the fact that these diseases mainly affect the poor in developing countries and development of treatments is inhibitive due to l...

Hope for major advance in fighting world killer disease

University of Leicester scientists are heading a worldwide research project which could revolutionise the diagnosis and treatment of diarrhoea in children in developing countries. The four-year project, the results of which are now being piloted in four hospitals in India, will offer a means of i...

Three-in-one virus killer prevents common, often fatal infections

A novel combination therapy drastically reduces the infection rate of three viruses ?and risk of death ?in transplant patients with compromised immune systems. The findings, to be reported in the Nov. 1 print edition of Nature Medicine, originate from a study conducted at Baylor College of Medicine...

How HIV 'exhausts' killer T cells

American and South African scientists working at the epicenter of the AIDS epidemic in South Africa have discovered how the human immunodeficiency virus (HIV) "exhausts" killer T cells that would otherwise attack the virus. The researchers found that HIV can simply "turn off" fully functional T cel...

Newly discovered killer cell fights cancer

A mouse immune cell that plays dual roles as both assassin and messenger, normally the job of two separate cells, has been discovered by an international team of researchers from the United States and France. The discovery has triggered a race among scientists to find a human equivalent of the mul...

Pain killer fights breast cancer by targeting key enzyme

A pain–killing medication appears to halt the production of an enzyme that is key to a common form of breast cancer, a new study using tissue cultures suggests. The drug is called nimesulide. In laboratory experiments on breast cancer cells, scientists found that derivatives of nimesulide stopped...

Secret sex life of killer fungus?

Aspergillus fumigatus is a medically important fungus, causing potentially life-threatening infections in patients with weakened immune systems. It is also a major cause of respiratory allergy, and it is implicated in asthma as well. The fungus has always been thought to lack the ability to reprodu...

Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells

Natural killer (NK) immune system cells can be genetically modified to brandish a powerful "on-switch" that prompts them to aggressively attack and kill leukemic cells. This finding, from researchers at St. Jude Children's Research Hospital, suggests a way to improve the outcome of children who rec...

Genetically modified natural killer immune cells attack, kill leukemia cells

Natural killer (NK) immune system cells can be genetically modified to brandish a powerful "on-switch" that prompts them to aggressively attack and kill leukemic cells. This finding, from researchers at St. Jude Children's Research Hospital, suggests a way to improve the outcome of children who rec...

Common cancer gene sends death order to tiny killer

Scientists at Johns Hopkins have discovered one way the p53 gene does what it's known for—stopping the colon cancer cells. Their report will be published in the June 8 issue of Molecular Cell. The research team identified a tiny bit of genetic code, a microRNA called miR-34a that participates i...

REGiMMUNE presents enhanced efficacy data in preclinical transplantation models

... a holy grail in transplantation." KRN7000, a synthetic derivative of alpha-galactosylceramide, is a small molecule that potently activates natural killer T (NKT) cells. RGI-2001 is a proprietary liposomal formulation of KRN7000. RGI-2001 monotherapy has shown to induce antigen-specific immune suppressi...

Novel vaccine approach offers hope in fight against HIV

...ealization. Most attempts at developing an HIV vaccine have used substances aimed at stimulating the body's immune system to produce antibodies or killer cells that would eliminate the virus before or after it infected cells in the body. However, clinical trials have been disappointing. HIV vaccines hav...

Indigenous peoples at world summit to share climate change observations, coping techniques

...s. Traditional knowledge of fire, meanwhile, is helping to create more effective strategies for year round forest management and reducing the risk of killer wild fires. Interestingly, in a world first, the aborigines of Western Arnhem Land have used traditional fire practices to reduce greenhouse gas em...

HIV pays a price for invisibility

...lled HLA (short for human leukocyte antigen) alert killer T cells by displaying bits of the virus on the sur... people with some other HLA variantslikely because killer T cells in these individuals are quick to attack i...uence, most likely because the benefit of avoiding killer T cells no longer outweighed the cost of reduced r...

Right whale sedation enables disentanglement effort

...ugh the clinical range until they found a safe and effective level. "Our prior experience with using these drugs safely in dolphins, beluga whales, killer whales and other species gave us the initial levels of sedatives to start with," said Mike Walsh a veterinarian and associate director of the Universi...

Dealing with taxonomic uncertainty for threatened and endangered species

...ylor illustrates the problem of taxonomic uncertainty with a case involving killer whales, which will likely be separated into multiple species or sub-species. The petition to list Southern Resident killer whales under the ESA revolved not around risk but rather on whether these w...

How Toxoplasma gondii gets noticed

...cialized vesicles inside infected host cells, but the process by which peptides from the trapped bugs are processed by infected cells and presented to killer T cells is mysterious. Here, Romina Goldszmid and her colleagues at the National Institutes of Health in Bethesda use T. gondii infections in m...

The heart disease mutation carried by 60 million

... Heart disease is the number one killer in the world and India carries more than its share of this burden. Moreover, the problem is set to rise: it is predicted that by 2010 India's populati...

Call Stephen Michnick a gene grammarian

... The raison d'tre of his work is to understand the fundamental chemistry of life, pinpoint where diseases begin and map out where they can be stopped killer illnesses such as cancer and Alzheimer's. "We think of genes and proteins interact in the same manner as people process sentences," says Dr. Michn...

American Library Association names NJIT prof’s Whale Music book a top ten

...inet while playing and recording interspecies duets with the melodic mammals. The corollary compact disc Whale Music featuring the sounds of beluga, killer and humpback whales can be heard at http://cdbaby.com/cd/davidrothenberg2 , iTunes or www.thousandmilesong.com . The musical tract includes a n...

Feed a cold, feed a fever: Research shows calorie cut makes it harder to fight flu

...dy must rely on cells that will kill the virus," Gardner said. "The natural killer cells are important in controlling the early stages of virus infection, bec...fluenza, and their bodies are not prepared to produce the amount of natural killer cells needed to combat the stress of fighting an infection." In Gardner'...

Hypertension develops early, silently, in African-American men

...iversity of Seoul. 'Silent killer' African-American men have higher levels of hypertension than white men. Hypertension is known as the silent killer because it can develop without the individual knowing it. According to the U.S. Centers for Disease Control and Prevention, hypertension is a major ri...

Forced evolution: Can we mutate viruses to death?

... HOUSTON -- Nov. 10, 2008 -- It sounds like a science fiction movie: A killer contagion threatens the Earth, but scientists save the day with a designer drug that forces the virus to mutate itself out of existence. The killer disease? Still a fiction. The drug? It could become a reality thanks to a n...

Researchers use chemical from medicinal plants to fight HIV

...example, the so-called "killer" CD8 T-cells that help fight infection have unique receptors for particular antigens. When a virus enters the body, the killer T-cells whose receptors recognize that virus create, through division, versions of themselves that fight the invader. Generally, the telomeres ...

Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida

...TS OF 156th ACOUSTICAL SOCIETY MEETING: 1) killer Whales Picky about their Salmon 2) Giving a ...ing Pitch Perception May Enhance Learning 1) killer WHALES PICKY ABOUT THEIR SALMON killer whales swimming the waters off British Columbia an...

Polarized light guides cholera-carrying midges that contaminate water supplies

... Cholera is a major killer and since the first pandemic in the early 19th century it has claimed millions of lives. According to Amit Lerner from The Hebrew University of Jerusa...
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