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Interactions in Biological News

Research explores interactions between nanomaterials, biological systems

The recent explosion in the development of nanomaterials with enhanced performance characteristics for use in commercial and medical applications has increased the likelihood of people coming into direct contact with these materials. There are currently more than 800 products on the market in...

Researchers 'unzip' molecules to measure interactions keeping DNA packed in cells

ITHACA, N.Y. Anyone who has ever battled a stuck zipper knows it's a good idea to see what's stuck, where and how badly -- and then to pull hard. A Cornell research team's experiments involve the "unzipping" of single DNA molecules. By mapping the hiccups, stoppages and forces along the way, th...

Social interactions can alter gene expression in the brain, and vice versa

Our DNA determines a lot about who we are and how we play with others, but recent studies of social animals (birds and bees, among others) show that the interaction between genes and behavior is more of a two-way street than most of us realize. This is not a new idea to neuroscience, but one th...

New method provides panoramic view of protein-RNA interactions in living cells

DNA, it has turned out, isn't all it was cracked up to be. In recent years we learned that the molecule of life, the discovery of the 20th century, did not -- could not -- by itself explain the huge differences in complexity between a human and a worm. Forced to look elsewhere, scientists turned t...

Penn biophysicists create new model for protein-cholesterol interactions in brain and muscle tissue

PHILADELPHIA - Biophysicists at the University of Pennsylvania have used 3,200 computer processors and long-established data on cholesterol's role in the function of proteins to clarify the mysterious interaction between cholesterol and neurotransmitter receptors. The results provide a new model o...

ESF conference probes water's mysterious interactions at molecular level

Some of the most challenging problems in science concern the behaviour of the most commonplace compound on the planets surface - water. But some of the mysteries are now being unravelled by the latest analysis and imaging techniques in an unfolding story that was presented at a recent conference o...

Workshop assesses interactions between climate, forests and land use in the Amazon Basin

On February 25 and 26, over 50 scientists gathered for a two-day workshop in Manaus, Brazil, to discuss the current state of knowledge on the feedbacks between deforestation and climate in the Amazon and what research is required to avoid catastrophic change. Collaborators from the Woods Hole Rese...

Rong Li Lab reports protein interactions of MAP kinase signaling pathway

The Stowers Institutes Rong Li Lab, in collaboration with the Institutes Imaging Center, has achieved a quantitative in vivo measurement of the dynamic protein-protein interactions in the mitogen-activated protein (MAP) kinase cascade signaling pathway, which is critical to growth and differentiat...

New technology illuminates protein interactions in living cells

New Haven, Conn. While fluorescence has long been used to tag biological molecules, a new technology developed at Yale allows researchers to use tiny fluorescent probes to rapidly detect and identify protein interactions within living cells while avoiding the biological disruption of existing met...

Keck Foundation funds study of biological interactions with nanomaterials

The University of Oregon has received a $1.6 million grant from the W.M. Keck Foundation to explore the biological effects of exposure to precisely engineered nanoparticles that are being designed for diagnostic and therapeutic uses. The three-year grant from the Keck Foundations medical resear...

Skin oil -- ozone interactions worsen air quality in airplanes

Airline passengers and crews who gripe about poor cabin air quality could have a new culprit to blame: the oils on their skin, hair and clothing. A study in the current issue of ACS Environmental Science & Technology suggests interactions between body oils and ozone found in airplane cabins could ...

Hidden interactions between predators and prey: evolution causes cryptic dynamics in ecology

When the populations of two species oscillate together (for example, predators and prey), its a good bet that they are tightly coupled ecologically. A famous example is the Canadian lynx and snowshoe hare, documented in the trapping records of the Hudsons Bay Company. But is the opposite also true...

New windows opened on cell-to-cell interactions

Applying biological molecules from cell membranes to the surfaces of artificial materials is opening peepholes on the very basics of cell-to-cell interaction. Two recently published papers by a University of Oregon biophysicist and colleagues suggest that putting lipids and other cell membrane ...

Photonic crystal biosensors detect protein-DNA interactions

CHAMPAIGN, Ill. Scientists at the University of Illinois have developed a new class of disposable, microplate-based optical biosensors capable of detecting protein-DNA interactions. Based on the properties of photonic crystals, the biosensors are suitable for the rapid identification of inhibitor...

Stowers Proteomics Center devises method for assigning probabilities to human protein interactions

The Stowers Institutes Proteomics Center has published a novel method of using normalized spectral counts derived from a series of affinity purifications analyzed by mass spectrometry (APMS) to generate a probabilistic measure of the preference of proteins to associate with one another. The ...

New Argonne study may shed light on protein-drug interactions

ARGONNE, Ill. (January 15, 2008) -- Proteins, the biological molecules involved in virtually every action of every organism, may themselves move in surprising ways, according to a recent study from the U.S. Department of Energys Argonne National Laboratory that may shed new light on how proteins i...

Small molecule interactions were central to the origin of life

In an important new paper forthcoming in the June issue of The Quarterly Review of Biology, Robert Shapiro (New York University) argues against the widely held theory that the origin of life began with the spontaneous appearance of a large, replicating molecule such as RNA. Instead, Shapiro raises...

APS lecturer shows rare video of 'teacher-student' immune cell interactions in live animal

The saying goes that a picture is worth a thousand words. But these pictures could one day be worth much more -- the lives saved by the development of new vaccines. Harvard University researcher Ulrich H. von Andrian showed the immune system of a live mouse being challenged by a foreign microbe d...

U of MN researchers develop way to visualize synchronized interactions of nerve cells in the brain

Researchers at the University of Minnesota Medical School and the Brain Sciences Center at the Minneapolis VA Medical Center have discovered a new way to assess how brain networks act together. Work funded by the MIND Institute (New Mexico) led Apostolos P. Georgopoulos, M.D., Ph.D., professor ...

A real time look at interactions between RNA and proteins

For the first time, researchers can now peer inside intact cells to not only identify RNA-binding proteins, but also observe–in real-time–the intricate activities of these special molecules that make them key players in managing some of the cell's most basic functions. Researchers at the University...

Complex gene interactions account for autism risk

Using a novel analysis of the interactions among related genes, Duke University Medical Center researchers have uncovered some of the first evidence that complex genetic interactions account for autism risk. The Duke team found that the brain mechanism that normally stops or slows nerve impulses co...

Computational verification of protein-protein interactions by orthologous co-expression

In the March 3 issue of Nature, Johns Hopkins researchers report that two proteins best known for very different activities actually come together to turn the liver into a sugar-producing factory when food is scarce. Because the liver's production of sugar is a damaging problem in people with diabe...

Virus-host interactions at sea effect global photosynthesis

Agilent Technologies Inc. (NYSE: A) today announced that it has for the first time released the chip design, probe sequence and annotation information for all of its microarrays. The release of this information is expected to improve cross-laboratory experimental research and cross-platform data co...

Scientists find universal rules for food-web stability

... Dieckmann. "Systems with fewer species are more stable if there are strong interactions between some species, but only weak interactions between others. For food webs with many species, exactly the opposite is tr...

Carnegie donates landmark clones to biology

...he information explosion, it's remarkable that so little is known about the interactions that proteins have with each other and the protective membrane that surroun...AMT1;1). This protein portion is called the C-terminus and it regulates the interactions of the pore-like structures at the membrane surface in plants. In this stud...

AGU journal highlights -- Aug. 6, 2009

...es of less than 25 days. This fundamental difference will help scientists understand the mechanics of how stratospheric ozone becomes depleted through interactions with these short-lived compounds. Title: Process regulating short-lived species in the tropical tropopause layer Authors: A. Gettleman and M. P...

Symposium to discuss geoengineering to fight climate change at the ESA Annual Meeting

...missions at a relatively low cost. He notes, however, that some potential risks of geologic sequestration include carbon leakage and the potential for interactions with groundwater. But on the planetary scale, most ecologists are skeptical of climate engineering. "Playing with the Earth's climate is a danger...

Animal and plant communication at the ESA Annual Meeting

...eriment is the first to quantify bird predation on specialist and generalist herbivores, and he hopes it will spark further research. He says that the interactions among the three trophic levels plants, herbivores and predators are the key to understanding the species' ecology and evolution. "Food webs are ...

UCSF researchers identify new drug target for Kaposi's sarcoma

...drug discovery, Craik said, by making target receptors that were biologically validated, but then deemed undruggable, more attractive. Protein-protein interactions have been researched as drug targets against a range of diseases, from certain cancers to neurodegenerative diseases. This advance could enable resear...

Ants more rational than humans

...cal outcome is based on apparent constraint: most individual ants know of only a single option, and the colony's collective choice self-organizes from interactions among many poorly-informed ants," says Pratt, an assistant professor in the School of Life Sciences in ASU's College of Liberal Arts and Sciences. ...

Parasitic worms make sex worthwhile

...lutionary biologists have long wondered why clonal reproduction does not replace sexual reproduction in natural populations. Our studies suggest that interactions with parasites might be part of the answer, because genetically variable sexual individuals might be more likely to escape infection." The biologis...

Noise pollution negatively affects woodland bird communities, says CU-Boulder study

...ad author on a study published online July 23 in Current Biology . "This is the first study to show that noise pollution causes changes in species interactions within bird communities," said Francis of CU-Boulder's Department of Ecology and Evolutionary Biology. "Since noise pollution can be a major cause of ...

C. difficile spores spread superbug

...vides," says Dr Fiona Cooke, working in the Department of Medical Microbiology at Addenbrooke's Hospital, Cambridge, "is a better understanding of the interactions between C. difficile , the intestinal microbiota and the immune system of the host - in this case the mouse - primarily in response to antibiotic tre...

Reviews of microbial gene language published in special issue of Trends in Microbiology

...abulary to describe disease-related and beneficial interactions between a microbe and its host. By allowing scient...inuum of broadly-defined, symbiotic microbial-host interactions ranging from detrimental to beneficial. Since all ...w Gene Ontology can be used to dissect the complex interactions involved when pathogens invade their hosts and lea...

UA pharmacy research shows prescribers miss potentially dangerous drug pairs

...drug pairs were contraindicated. "The study found a very low rate of recognition of these particular interactions," says Malone, "and some of these interactions are very common." Use of several of the contraindicated drug pairs could be dangerous. For example, taking sildenafil (Viagra) and nitrates, such a...

New advance in revolutionary 'bullet fingerprinting' technique

...e that he believes is so simple, which can explain why it has been overlooked until now. The technique involves studying the chemical and physical interactions occurring between the metal and the fingerprint sweat deposit. Using advanced surface imaging techniques, such as an Atomic Force Microscope, nanoscal...

Mount Sinai's Dr. Benjamin tenOever to be honored by White House

...f science, and technology and a commitment to community service. Dr. tenOever and his team study cellular response to RNA virus infectionsthe genetic interactions that occur within cells attacked by virusas well as processes that render cells resistant to infection, in the hope of reducing the global burden from...

22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey

...goal of neuropsychopharmacology is to develop specific therapeutic agents to regulate the biological mechanisms of mental disorders, i.e. the neuronal interactions that give rise to these disorders. For this purpose, neuropsychopharmacology investigates the effect of drugs on the central nervous system (CNS) and ...

2 Fred Hutchinson Cancer Research Center scientists receive Presidential Early Career Award

...and consequences of these genetic conflicts in yeast, fruit flies and other model organisms. His work has offered novel explanations for host-pathogen interactions and for the evolution of structural DNA elements (centromeres) that are critical for proper cell division. Recently, Malik and colleagues have turne...

Research shows that 'invisible hand' guides evolution of cooperative turn-taking

... "Turn-taking is initiated only after a species has evolved at least two genetically different types that behave differently in initial, uncoordinated interactions with others. Then as soon as a pair coordinates by chance, they instinctively begin to play 'tit for tat'. This locks them into mutually beneficial co...
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