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Protein identified as critical to insulating the body's wiring could also become treatment target

AUGUSTA, Ga. - A new protein identified as critical to insulating the wiring that connects the brain and body could one day be a treatment target for divergent diseases, from rare ones that lower the pain threshold to cancer, Medical College of Georgia researchers say. They report this week in ...

Genes that influence start of menstruation identified for first time

Researchers from the Peninsula Medical School, along with collaborators from research institutions across Europe and the United States, have for the first time identified two genes that are involved in determining when girls begin menstruation. The work will be published in Nature Genetics this ...

Genetic risk factors identified for sudden cardiac death

Building on these findings, the Helmholtz scientists and their clinical partners want to obtain further insights into the pathogenesic mechanisms of the disease and gain perspectives for early diagnosis and therapy. The results of the genome-wide study have been published online in the journal Na...

Ten genes identified in connection with sudden cardiac death

ANN ARBOR, Mich.---You're sitting at your desk and suddenly your heart is beating in overdrive or worse, lurching along like a car on fumes. It is a shocking, uncomfortable and frightening sensation. Irregular heart rhythms are a common cause of sudden cardiac death or SCD, a condition that ac...

Regulatory molecule for tumor formation or suppression identified by Singapore, US researchers

One of the small regulatory molecules, named microRNA-125b, is a novel regulator of p53, an important protein that safeguards cells against cancers, Singapore and U.S. scientists report in the March 17, 2009 issue of the journal Genes & Development . The scientists found that during embryonic ...

Genes identified that are linked to spinal disc degeneration

Lumbar disc degeneration is an uncomfortable condition that affects millions of people, but two University of Alberta researchers have identified some of the genes that are causing problems. Michele Crites-Battie and Tapio Videman, in the Faculty of Rehabilitation Medicine, have discove...

New and unexpected mechanism identified how the brain responds to stress

Calgary, AB -- Chronic stress takes a physical and emotional toll on our bodies and scientists are working on piecing together a medical puzzle to understand how we respond to stress at the cellular level in the brain. Being able to quickly and successfully respond to stress is essential for surv...

Newly identified gene powerful predictor of colon cancer metastasis

Cancer Researchers at the Max Delbrck Center for Molecular Medicine (MDC) Berlin-Buch and the Charit Universitts Medizin Berlin (Germany) have identified a gene which enables them to predict for the first time with high probability if colon cancer is going to metastasize. Assistant Professor Dr. ...

Bipolar disorder genes, pathways identified by Indiana University neuroscientists

INDIANAPOLIS Neuroscientists at the Indiana University School of Medicine have created the first comprehensive map of genes likely to be involved in bipolar disorder, according to research published online Nov. 21 in the American Journal of Medical Genetics . The researchers combined data fro...

New therapeutic target identified for rheumatoid arthritis

Researchers at Hospital for Special Surgery have identified a potential new therapeutic target that could be used to treat inflammatory disorders, such as rheumatoid arthritis. The study, published online ahead of print, will appear Nov. 15 in the journal Immunity . Specifically, the study re...

Protein identified that plays role in blood flow

COLUMBIA, Mo. For years, researchers have known that high blood pressure causes blood vessels to contract and low blood pressure causes blood vessels to relax. Until recently, however, researchers did not have the tools to determine the exact proteins responsible for this phenomenon. Now, using a...

New gene variant identified for nondiabetic end stage renal disease in African-Americans

Scientists at Johns Hopkins schools of Public Health and Medicine have, for the first time, identified variants in the gene MYH9 that are associated with increased risk for non-diabetic end stage renal disease (ESRD,) which is the near-loss of kidney function leading to either dialysis of transpla...

Large reservoir of mitochondrial DNA mutations identified in humans

Blacksburg, Va. Researchers at the University of Newcastle, England, and the Virginia Bioinformatics Institute at Virginia Tech in the United States have revealed a large reservoir of mitochondrial DNA mutations present in the general population. Clinical analysis of blood samples from almost 3,...

A new cellular pathway linked to cancer is identified by NYU researchers

NEW YORK, July 24, 2008 In the life of a cell, the response to DNA damage determines whether the cell is fated to pause and repair itself, commit suicide, or grow uncontrollably, a route leading to cancer. In a new study, published in the July 25th issue of Cell , scientists at NYU Langone Medic...

TG2 identified as potential therapeutic target in chemo-resistant ovarian cancer

HOUSTON, TX Scientists from The University of Texas M. D. Anderson Cancer Center have found overexpression of tissue type transglutaminase (TG2) in ovarian cancer is associated with increased tumor cell growth and adhesion, resistance to chemotherapy and lower overall survival rates. When resea...

Mechanism and function of humor identified by new evolutionary theory

A new publication answers centuries' old questions regarding the mechanism and function of humour, identifying the reason humour is common to all human societies, its fundamental role in the evolution of homo sapiens and its continuing importance in the cognitive development of infants. Alastai...

Newly identified role for 'power plants' in human cells could lead to targeted therapies

COLUMBUS, Ohio Scientists have determined that human cells are able to shift important gene products into their own mitochondria, considered the power plants of cells. The finding could eventually lead to therapies for dozens of diseases. The gene products, known as tRNAs, assemble amino acids...

Promising new drug targets identified for Huntington's disease

Research funded by the Wellcome Trust has provided a number of promising new drug targets for Huntington's disease, a neurodegenerative disease. Scientists at the University of Cambridge have identified a number of candidate drugs to investigate further which encourage cells to "eat" the malformed...

DNA 'barcode' identified for plants

A 'barcode' gene that can be used to distinguish between the majority of plant species on Earth has been identified by scientists who publish their findings in the Proceedings of the National Academy of Sciences journal today (Monday 4 February 2008). This gene, which can be used to identify pl...

Novel mechanism for long-term learning identified by Carnegie Mellon researchers

PITTSBURGH Practice makes perfect or at least thats what were told as we struggle through endless rounds of multiplication tables, goal kicks and piano scales and it seems, based on the personal experience of many, to be true. Thats why neuroscientists have been perplexed by data showing that ...

Cognitive, genetic clues identified in imaging study of alcohol addiction

People with clinical addictions know first-hand the ravages the disease can take on almost every aspect of their lives. So why do they continue addictive behaviors, even after a period of peaceable abstinence" Some answers appear rooted in regions of the brain active during decision making. ...

Mutant gene identified as villain in hardening of the arteries

New Haven, Conn.A genetic mutation expands lesions in the aorta and promotes coronary atherosclerosis, more commonly known as hardening of the arteries, according to a study by Yale School of Medicine in Cell Metabolism. The researchers found that mice engineered without the Akt1 gene and f...

Best treatment identified to reduce deadly Staph infections

LAS VEGAS One type of over-the-counter product for topical wound care is more effective than others in killing methicillin-resistant Staphylococcus aureus bacteria, or MRSA, which is potentially deadly and in recent years has moved from its historic hospital setting to a much broader public conce...

Genes identified to protect brassicas from damaging disease

Scientists have identified a new way to breed brassicas, which include broccoli, cabbage and oilseed rape, resistant to a damaging virus. Their discovery has characterised a form of resistance that appears to be durable, broad-spectrum and unlikely to be overcome by the virus over time. Turnip mos...

The reservoir of Marburg virus identified in a species of fruit bat

The Marburg virus, like its fearsome cousin Ebola, belongs to the Filoviridae family. It carries the name of the German town where it was first detected in 1967, after a mysterious epidemic had hit employees of the Behring laboratory. The workers had been contaminated as they took organ samples fr...

Brain difference in psychopaths identified

Professor Declan Murphy and colleagues Dr Michael Craig and Dr Marco Catani from the Institute of Psychiatry at King's College London have found differences in the brain which may provide a biological explanation for psychopathy. The results of their study are outlined in the paper 'Altered connec...

Protein that promotes cancer cell growth identified

LA JOLLA, Calif., July 24, 2009 Scientists at Burnham Institute for Medical Research (Burnham) have found that the Caspase-8 protein, long known to play a major role in promoting programmed cell death (apoptosis), helps relay signals that can cause cancer cells to proliferate, migrate and invade ...

Brain protein central to both Parkinson's, drug addiction identified

Scientists have identified a protein that appears not only to be central to the process that causes Parkinson's disease but could also play a role in muting the high from methamphetamine and other addictive drugs. The action of the protein, known as organic cation transporter 3 or oct3, fills a...

Cause of mussel poisoning identified

The origin of the neurotoxin azaspiracid has finally been identified after a search for more than a decade. The azaspiracid toxin group can cause severe poisoning in human consumers of mussels after being enriched in the shellfish tissues. The scientific periodical European Journal of Phycology ...

New greenhouse gas identified

CAMBRIDGE, Mass.--A gas used for fumigation has the potential to contribute significantly to future greenhouse warming, but because its production has not yet reached high levels there is still time to nip this potential contributor in the bud, according to an international team of researchers. ...

Dangerous printer particles identified

The identity and origin of tiny, potentially hazardous particles emitted from common laser printers have been revealed by a new study at Queensland University of Technology. Professor Lidia Morawska from QUT's International Laboratory for Air Quality and Health lead the study to answer questio...

Chemopreventive agents in black raspberries identified

PHILADELPHIA A study published in Cancer Prevention Research , a journal of the American Association for Cancer Research, identifies components of black raspberries with chemopreventive potential. Researchers at the Ohio State Comprehensive Cancer Center found that anthocyanins, a class of fl...

New 'control knobs' for stem cells identified

MEDFORD/SOMERVILLE, Mass. Natural changes in voltage that occur across the membrane of adult human stem cells are a powerful controlling factor in the process by which these stem cells differentiate, according to research published by Tufts University scientists. Tufts doctoral student Sarah ...

Genetic predictors of esophageal cancer identified

PHILADELPHIA Researchers have identified 11 genotypes that may increase esophageal cancer risk, according to research published in the November issue of Cancer Prevention Research, a journal of the American Association for Cancer Research. "We observed a significantly increased risk of esoph...

Gene with probable role in human susceptibility to pulmonary tuberculosis identified

A new gene that may confer susceptibility to pulmonary tuberculosis has been identified by Genome Institute of Singapore (GIS) researchers and their collaborators in The Netherlands, Indonesia, United Kingdom, and the Russian Federation. In the current j PLoS Genetics , the scientists report ...

Key component of debilitating lung disease identified

For the first time, researchers have demonstrated a close correlation between the decline in a key component of the lung's antioxidant defense system and the progression of chronic obstructive pulmonary disease (COPD) in humans. COPD is a degenerative condition that decreases the flow of air throu...

Likely cause of postpartum blues and depression identified

Unique biochemical crosstalk that enables a fetus to get nutrition and oxygen from its mother's blood just may cause common postpartum blues, researchers say. That crosstalk allows the mother's blood to flow out of the uterine artery and get just a single cell layer away from the fetus' blood, ...

Advances in the field of schizophrenia research: New genetic factors identified

Schizophrenia is one of the most serious mental illnesses and is accompanied by symptoms that include delusions and blunted affect. Environmental as well as genetic factors form a complex interplay that leads to the illness. Two papers published in the Internet editions of the professional journal...

Potential new drug target to fight tuberculosis identified

NEW YORK (July 29, 2008) -- With antibiotic resistance on the rise, tuberculosis is emerging as a bigger global health threat than ever before. But now, innovative research at Weill Cornell Medical College suggests that Mycobacterium tuberculosis has an as yet unsuspected weakness -- one tha...

Threatened or invasive? Species' fates identified

A new ecological study led by a University of Adelaide researcher should help identify species prone to extinction under environmental change, and species that are likely to become a pest. The study, the first of its kind, was published this week online in the British Ecological Society's prest...
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Breaking Biology News(10 mins):3rd annual Golden Goose award ceremony honors 8 researchers; Unusual work had big results 2Counting fish teeth reveals regulatory DNA changes behind rapid evolution, adaptation 2Counting fish teeth reveals regulatory DNA changes behind rapid evolution, adaptation 3UCLA scientists play key role in developing new Santa Ana Wildfire Threat Index 2
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Breaking Medicine News(10 mins):Health News:Quirk Awarded the Alex Ormond, Jr. Leadership Award by the Savannah Science Seminar 2Health News:Survey: Fortune 500 employees can expect to pay more for health insurance 2Health News:Survey: Fortune 500 employees can expect to pay more for health insurance 3Health News:Award-Winning Cooking Magazine for Kids Challenges Former White House Pastry Chef and 10-Year-Old Chef to Cook Up a Healthy Snack 2Health News:Award-Winning Cooking Magazine for Kids Challenges Former White House Pastry Chef and 10-Year-Old Chef to Cook Up a Healthy Snack 3Health News:United Way Celebrates “Best Chefs and Fine Wines” at Sold-Out Culinary Event 2Health News:United Way Celebrates “Best Chefs and Fine Wines” at Sold-Out Culinary Event 3Health News:A new way to prevent the spread of devastating diseases 2Health News:A new way to prevent the spread of devastating diseases 3Health News:A new way to prevent the spread of devastating diseases 4Health News:A new way to prevent the spread of devastating diseases 5
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