INNO

Innovative collaboration brings Arctic science into the classroom

An upcoming expedition to study the Yukon and Mackenzie Rivers is not simply a research project for R. Max Holmes, an associate scientist at The Woods Hole Research Center. It is also a means to integrate education and outreach into his work. In June and July, Dr. Holmes, an ecosystem scientist with broad interests in the responses and feedbacks of ecosystems to environmental and global ch...

Innovative coating could give medical implants a longer life

By mimicking an adhesive protein secreted by mussels and a polymer that repels cells and proteins, researchers at Northwestern University have designed a versatile new two-sided coating that could breathe life into medical implants. Currently the longevity of certain medical implants suffers because bacteria, cells and proteins in the body gradually accumulate on the devices (known as fou...

Innocuous intestinal bacteria may be reservoir for resistance

"Harmless" bacteria in the digestive tracts of dairy cows, may not be so harmless after all. They may be a reservoir for antibiotic resistance genes that can be transferred to more harmful, disease-causing bacteria, according to research presented today at the 106th General Meeting of the American Society for Microbiology in Orlando, Florida. "There is concern that veterinary therapeutic...

Innovative method for creating a human cytomegalovirus vaccine outlined

Each year, about 40,000 children are born infected with human cytomegalovirus, or CMV, and about 8,000 of these children suffer permanent disabilities due to the virus ?almost one an hour. These disabilities can include hearing loss, vision loss, mental disability, a lack of coordination, and seizures. According to the Centers for Disease Control and Prevention, CMV is as common a cause of seriou...

A giant among minnows: Giant danio can keep growing

Two fish that share much in common genetically appear to have markedly different abilities to grow, a finding that could provide a new way to research such disparate areas as muscle wasting disease and fish farming, a new study shows. The study in the November issue of the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, finds that the giant danio, unlike...

Study offers innovative profile of enzyme that aids tumor growth

"Using a combination of enzyme activity and metabolite profiling, we determined that this protein-whose function was previously unknown-serves as a key regulator of a lipid signaling network that contributes to cancer," said Benjamin F. Cravatt, a Scripps Research professor and a member of its Skaggs Institute for Chemical Biology who led the study. "The heightened expression of KIAA1363 in sever...

Innovative movies show real-time immune-cell activity within tumors

Using advanced new microscopy techniques in concert with sophisticated transgenic technologies, scientists at The Wistar Institute have for the first time created three-dimensional, time-lapse movies showing immune cells targeting cancer cells in live tumor tissues. In recorded experiments, immune cells called T cells can be seen actively migrating though tissues, making direct contact with tumor...

Innovative smallpox vaccine research study to be conducted at Case Medical Center

The current FDA-approved vaccine, D...