New drug may reduce heart attack damage
A novel drug that targets a master disease-causing gene can dramatically reduce heart
muscle damage after a heart
attack and may lead to significantly improved patient outcomes, researchers at the University of New South Wales (UNSW) have shown.
The drug, known as Dz13, specifically targets and...
UAB students' Nintendo Wii CPR earns American Heart Association support
BIRMINGHAM, Ala. The American Heart
Association has pledged $50,000 to fund the work of University of Alabama at Birmingham (UAB) biomedical engineering undergraduate students who are working to develop a computer program that teaches CPR using hand-held remote controls from the Nintendo Wii vide...
Pitt team finds molecule that regulates heart size by using zebrafish screening model
PITTSBURGH, July 5 Using zebrafish, researchers at the University of Pittsburgh have identified and described an enzyme inhibitor that allows them to increase the number of cardiac progenitor cells and therefore influence the size of the developing heart. The findings are described in the advance...
Following the dietary guidelines may slow heart disease in women
The Dietary Guidelines for Americans (DGA) provide guidance to promote health and reduce risk of chronic diseases. However, what evidence is there that following the DGA optimizes health? Is this advice useful for individuals already in poor health? To study these questions, researchers at the USD...
New device detects heart disease using less than one drop of blood
Testing people for heart
disease might be just a finger prick away thanks to a new credit card-sized device created by a team of researchers from Harvard and Northeastern universities in Boston. In a research report published online in The FASEB Journal ( http://www.fasebj.org ), they describe h...
NIH funds work at WPI on regenerating heart tissue and preventing urinary tract infections
WORCESTER, Mass. May 28, 2009 Congressman James McGovern, D-Massachusetts, today announced National Institutes of Health (NIH) awards for two researchers at Worcester Polytechnic Institute's Life Sciences and Bioengineering Center at Gateway Park.
Glenn Gaudette, PhD, assistant professor of b...
Adult bone marrow stem cells injected into skeletal muscle can repair heart tissue
BUFFALO, N.Y. -- University at Buffalo researchers have demonstrated for the first time that injecting adult bone marrow stem cells into skeletal muscle can repair cardiac tissue, reversing heart
Using an animal model, the researchers showed that this non-invasive procedure increased...
Genetic factors may predict depression in heart disease patients
PROVIDENCE, RI Individuals with heart
disease are twice as likely to suffer from depression as the general population, an association the medical community has largely been unable to explain. Now, a new study by researchers at The Miriam Hospital, in conjunction with The Montral Heart
Folic acid to prevent congenital heart defects
This release is available in French .
Montreal, May 14th 2009 - The Canadian policy of fortifying grain products with folic acid has already proved to be effective in preventing neural tube defects. The latest article published in the British Medical Journal by a group of researchers fr...
'Beating' heart machine expedites research and development of new surgical tools, techniques
A new machine developed at North Carolina State University makes an animal heart
pump much like a live heart
after it has been removed from the animal's body, allowing researchers to expedite the development of new tools and techniques for heart
surgery. The machine saves researchers time and mone...
Chemical found in medical devices impairs heart function
Researchers at the Johns Hopkins University School of Medicine have found that a chemical commonly used in the production of such medical plastic devices as intravenous (IV) bags and catheters can impair heart
function in rats. Appearing online this week in the American Journal of Physiology , th...
Gladstone scientists identify key factors in heart cell creation
Scientists at the Gladstone Institute of Cardiovascular Disease have identified for the first time key genetic factors that drive the process of generating new heart
cells. The discovery, reported in the current issue of the journal Nature , provides important new directions on how stem cells may...
Eating fatty fish once a week reduces men's risk of heart failure
BOSTON Eating salmon or other fatty fish just once a week helped reduce men's risk of heart
failure, adding to growing evidence that omega-3 fatty acids are of benefit to cardiac health. Led by researchers at Beth Israel Deaconess Medical Center (BIDMC) and reported in today's on-line issue of t...
A missing enzyme conveys major heart protection in pre-clinical work
DURHAM, N.C. Mice born without a certain enzyme can resist the normal effects of a heart
attack and retain nearly normal function in the heart's ventricles and still-oxygenated heart
tissue, according to a study by researchers at Duke University Medical Center.
The findings raise the possibil...
Inhaling a heart attack: How air pollution can cause heart disease
BETHESDA, Md. (March 23, 2009) We are used to thinking of heart
disease as a product of genetic factors or lifestyle choices, such as what we eat and how much we exercise. There is another road to heart
Accumulating evidence indicates that an increase in particulate air poll...
Simple test helps predict heart attack risk
SAN DIEGO, Calif. (March 10, 2009)The use of common and readily available screening testslike the ankle brachial index (ABI)along with traditional risk scoring systemssuch as the Framingham Risk Scorehas the potential to prevent devastating heart
attacks in thousands of individuals who are not ori...
Plasminogen activator inhibitor type-1 -- a potential link between heart failure and diabetes
Researchers at the University of Vermont Cardiovascular Research Institute, Colchester, Vermont have found that increased expression in the heart
of plasminogen activator inhibitor type-1 (PAI-1) is profibrotic. The results, which appear in the March 2009 issue of Experimental Biology and Medici...
High-fat diets inflame fat tissue around blood vessels, contribute to heart disease
CINCINNATIA study by researchers at the University of Cincinnati (UC) shows that high-fat diets, even if consumed for a short amount of time, can inflame fat tissue surrounding blood vessels, possibly contributing to cardiovascular disease.
These findings will be published in the Feb. 20 editio...
International study identifies gene variants associated with early heart attack
The largest study ever completed of genetic factors associated with heart
attacks has identified nine genetic regions three not previously described that appear to increase the risk for early-onset myocardial infarction. The report from the Myocardial Infarction Genetics Consortium, based on in...
While focusing on heart disease, researchers discover new tactic against fatal muscular dystrophy
NEW YORK (Feb. 8, 2009) Based on a striking similarity between heart
disease and Duchenne muscular dystrophy, researchers at Columbia University Medical Center have discovered that a new class of experimental drugs for heart
failure may also help treat the fatal muscular disorder.
At first gla...
UC Davis research shows that newly discovered drug reduces heart enlargement
DAVIS--Researchers at the University of California, Davis have discovered that a prototype drug reduces heart
enlargement, one of the most common causes of heart
failure, which occurs when the heart
can't pump enough blood throughout the body, affects 5 million people in the Un...
Researchers examine developing hearts in chickens to find solutions for human heart abnormalities
COLUMBIA, Mo. When it is head versus heart, the heart
comes first. The heart
is the first organ to develop and is critical in supplying blood to the rest of the body. Yet, little is known about the complex processes that regulate the heartbeat. By studying chickens' hearts, a University of Missou...
The heart disease mutation carried by 60 million Heart
disease is the number one killer in the world and India carries more than its share of this burden. Moreover, the problem is set to rise: it is predicted that by 2010 India's population will suffer approximately 60% of the world's heart
disease. Today, an international team of 25 scientists ...
Safe new therapy for genetic heart disease
Prague, Czech Republic A new clinical trial suggests that long-term use of candesartan, a drug currently used to treat hypertension, may significantly reduce the symptoms of genetic heart
disease. The related report by Penicka et al, "The effects of candesartan on left ventricular hypertrophy an...
Gene therapy reversed heart damage in heart failure
(PHILADELPHIA) Long-term gene therapy resulted in improved cardiac function and reversed deterioration of the heart
in rats with heart
failure, according to a recent study conducted by researchers at Thomas Jefferson University's Center for Translational Medicine. The study was published online i...
UT faculty members win American Heart Association awards for advancing research
Faculty members at The University of Texas Health Science Center at Houston (UTHSC-Houston) were honored for their work in the fight against heart
disease at the 2008 American Heart
Association's Scientific Sessions in New Orleans. Heart
disease is the nation's No. 1 killer.
UT faculty members ...
A low dose of caffeine when pregnant may damage the heart of offspring for a lifetime
A new study published online in The FASEB Journal shows that the equivalent of one dose of caffeine (just two cups of coffee) ingested during pregnancy may be enough to affect fetal heart
development and then reduce heart
function over the entire lifespan of the child. In addition, the researche...
Scientists find link between inflamed gums and heart disease
The next person who reminds you to floss might be your cardiologist instead of your dentist. Scientists have known for some time that a protein associated with inflammation (called CRP) is elevated in people who are at risk for heart
disease. But where's the inflammation coming from? A new researc...
Reducing the damage of a heart attack
NEW YORK (Dec. 15, 2008) -- In the aftermath of a heart
attack, the body's own defenses may contribute to future heart
failure. Authors of a new study believe they have identified a protein that plays an important role in a process that replaces dead heart
muscle with stiffening scar tissue. The r...
Preventing a broken heart: Research aims to reduce scarring from heart attacks
MADISON A heart
damaged by heart
attack is usually broken, at least partially, for good. The injury causes excessive scar tissue to form, and this plays a role in permanently keeping heart
muscle from working at full capacity.
Now researchers have identified a key molecule involved in control...
The genetic heart of the lipids
A new study presages a real aim of genetics: to look at whole populations to in order determine the significance of individual genetic variants for individual health. The research team, whose work is published in Nature Genetics , find six novel genetic variants that are associated with lipid lev...
Apple or pear shape is not main culprit to heart woes -- it's liver fat
For years, pear-shaped people who carry weight in the thighs and backside have been told they are at lower risk for high blood pressure and heart
disease than apple-shaped people who carry fat in the abdomen. But new findings from nutrition researchers at Washington University School of Medicine i...
Children's Hospital scientists achieve repair of injured heart muscle in lab tests of stem cells
Researchers at Children's Hospital of Pittsburgh of UPMC have been able to effectively repair damaged heart
muscle in an animal model using a novel population of stem cells they discovered that is derived from human skeletal muscle tissue.
The research team led by Johnny Huard, PhD transplant...
Vitamin C lowers levels of inflammation biomarker considered predictor of heart disease
Berkeley -- A new study led by researchers at the University of California, Berkeley, adds to the evidence that vitamin C supplements can lower concentrations of C-reactive protein (CRP), a central biomarker of inflammation that has been shown to be a powerful predictor of heart
disease and diabet...
OSA's ISP launches with research on breathing disorders and congenital heart defects
WASHINGTON, Oct. 30 -- Two groups of researchers, one in the United States and one in Australia, are announcing the development of new optical techniques for visualizing the invisible processes at work in several human diseases. The published results are the first to showcase the Optical Society's...
Grapes may aid a bunch of heart risk factors, animal study finds
ANN ARBOR, Mich. Could eating grapes help fight high blood pressure related to a salty diet? And could grapes calm other factors that are also related to heart
diseases such as heart
failure? A new University of Michigan Cardiovascular Center study suggests so.
The new study, published in the...
Researchers at UH explore use of fat cells as heart attack therapy
HOUSTON, Oct. 27, 2008 For those of us trained to read nutrition labels, conventional wisdom tells us that fat isn't good for the heart. But a team of University of Houston researchers has set out to use fat cells to beef up heart
muscles damaged by heart
attack and they're using an out-of-this-...
Drug-embedded microparticles bolster heart function in animal studies
Researchers at Emory University and Georgia Institute of Technology have developed tiny polymer beads that can slowly release anti-inflammatory drugs and break down into non-toxic components.
When injected into rats' hearts after a simulated heart
attack, the drug-embedded "microparticles" redu...
Embryonic heart exhibits impressive regenerative capacity
A new study demonstrates that the embryonic mouse heart
has an astounding capacity to regenerate, a phenomenon previously observed only in non-mammalian species. The research, published by Cell Press in the October 14th issue of the journal Developmental Cell , describes the previously unrecogniz...
Study provides insight on a common heart rhythm disorder
University of Iowa researchers and colleagues in France have identified a gene variant that causes a potentially fatal human heart
rhythm disorder called sinus node disease. Also known as "sick sinus syndrome," the disease affects approximately one in 600 heart
patients older than 65 and is respon...