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EMBL scientists develop first fully automated pipeline for multiprotein complex production

Most cellular processes are carried out by molecular machines that consist of many interacting proteins. These protein complexes lie at the heart of life science research, but they are notoriously hard to study. Their abundance is often too low to extract them directly from cells and generating th...

GEN reports biomanufacturers target a fully disposable process stream

New Rochelle, NY, March 4, 2009--The disposable bioprocessing market has moved far beyond plastic bags for buffer preparation toward a range of products for cell culture and upstream and downstream operations, reports Genetic Engineering & Biotechnology News (GEN). Increasing numbers of biomanuf...

URI researcher: China can't fully fix air quality problem for Olympics

NARRAGANSETT, R.I. July 14, 2008 The outlook for air quality in Beijing during the Olympics is borderline, and there's little that the Chinese government can do to improve it. That's the conclusion drawn by a University of Rhode Island atmospheric chemist who analyzed pollution data collected...

The Lancet publishes first clinical trial data of a fully bioabsorbable drug eluting stent

ABBOTT PARK, Ill., March 13, 2008 Data published today in The Lancet from ABSORB, the worlds first clinical trial of a fully bioabsorbable drug eluting stent for the treatment of coronary artery disease, demonstrated no stent thrombosis, no clinically driven target lesion revascularizations (re-t...

Cloned mice created from fully differentiated cells, a milestone in cloning research

New research dismisses the notion that adult stem cells are necessary for successful animal cloning, proving instead that cells that have completely evolved to a specific type not only can be used for cloning purposes, but they may be a better and more efficient starting point. As proof, researcher...

Ebola DNA vaccine produces immune responses in all fully vaccinated volunteers in Phase 1 trial

Vical Incorporated announced today that an Ebola vaccine candidate administered using Vical's proprietary DNA delivery technology was safe and well tolerated, and produced both antibody and T-cell Ebola-specific responses in all healthy volunteers who received the full 3 doses of vaccine. The Pha...

Candida albicans Genome Fully Annotated

Circulating stem cells play a minor role in repairing lung damage, according to a team of scientists who used male and female chromosomal differences to analyze the repair process in lung transplant patients. Reporting in today's edition of the journal Transplantation, lead author Dani Zander, M....

Carbon nanoparticles toxic to adult fruit flies but benign to young

...n nanoparticles are widely used in medicine, electronics, optics, materials science and architecture, but their health and environmental impact is not fully understood. In a series of experiments, researchers at Brown University sought to determine how carbon nanoparticles would affect fruit flies from...

UC San Diego engineer provides insights to decades-old DNA squabble

...inhibitors) that can modulate structure of chromatin around oncogenic genes so as to inhibit cancer progression, though their exact mechanisms are not fully known," Arya said. "The scientific community is quite fascinated by DNA and they tend to forget that DNA is rarely present in its naked double-str...

Global curbs on overfishing are beginning to work

...seeing recovery in overall ecosystem structure, even if some species aren't fully recovered yet. "But we can't rest on our laurels. Management methods nee...est Shelf region of Western Australia, although some species groups had not fully recovered. ...

UCSF researchers identify new drug target for Kaposi's sarcoma

...zymes known as proteases, however, including those for HIV and the herpes virus family, take the form of a dimer, or two identical halves much like a fully opened clamshell in their most stable state. Those proteases play an essential role in making the virus infectious, but require the two clamshell hal...

Nottinghamshire Police First Law Enforcement Agency to Deploy ForensicSoft in United Kingdom

...s-based boot environment to ensure a forensically sound preview, exploration and capture of the digital evidence. SAFE employs Microsoft Windows PE (a fully licensed copy is included) and is capable of running your favorite Windows-based forensic tools such as FTK, EnCase, X-Ways, and many more. With SAFE'...

Maternal, paternal genes' tug-of-war may last well into childhood

...and development in individuals with Silver-Russell syndrome, Prader-Willi syndrome, Temple syndrome, and Beckwith-Wiedemann syndrome is needed to more fully understand the role of genomic imprinting in such disorders. ...

Researchers capture bacterial infection on film

...emoved from this complex environment and cultured in a petri dish these signals are lost. Therefore it is really important to study whole organisms to fully understand how bacteria interact with their host." Dr Nick Waterfield, co-author on the study and Research Officer at the University of Bath, said:...

DOE-funded research projects win 46 R&D 100 Awards for 2009

...mart cars and medical sensing devices. Unlike traditional batteries, the PowerPlane UX Microbattery has a long life cycle even if it is frequently and fully discharged. (Jointly with Planar Energy Devices) SkyTrough Parabolic Trough Solar Concentrating Collector uses a lightweight and weatherproof r...

Vaccine blocks malaria transmission in lab experiments

...y and Immunology. For the study, the research team expressed full-length Pfs48/45 in E. coli bacteria to produce the vaccine. Previous attempts to fully express the protein had not been successful. The vaccine was first given to mice in the laboratory. The vaccine was also tested in non-human primates ...

Scripps-led study shows ocean health plays vital role in coral reef recovery

...ounding waters and reef were relatively healthy. In comparison, those corals living with excessive local impacts, such as pollution, were not able to fully recover after eight years. "You can imagine that when you are recovering from a sickness, it will take a lot longer if you don't eat well or get ...

Researchers design first model motor nerve system that's insulated and organized like the human body

...avel through myelinated and unmyelinated nerves to reveal how nerves malfunction as well as for spinal cord injury studies. "Being able to study these fully developed structures means we can really start looking at these things in a way that just wasn't possible before," commented Hickman. ...

$20 million NIH grant to transform clinical research at UIC

... program in 2006 to fund a national consortium of medical research institutions that now includes 39 leading centers in 23 states. When the program is fully implemented, about 60 centers will be connected with an annual budget of $500 million. The UIC center was established in 2007 to create new collabo...

M2SYS Technology to Offer Desktop Biometric Technology to Kronos Customers

...SYS Technology, www.m2sys.com , is a recognized industry leader in biometric identity management technology, delivering a wide range of customized, fully functional, turn-key fingerprint, finger vein, and other biometric software solutions for businesses and consumers. About Kronos Kronos is t...

ACS Technologies(TM) Selects M2SYS for Innovative Biometric Software

...SYS Technology, www.m2sys.com , is a recognized industry leader in biometric identity management technology, delivering a wide range of customized, fully functional, turn-key fingerprint, finger vein, and other biometric software solutions for businesses and consumers. About ACS Technologies ...

Research shows that 'invisible hand' guides evolution of cooperative turn-taking

... "tit for tat" copying in each time period whatever the other individual did in the previous period can explain synchronized cooperation, but cannot fully explain turn-taking. "For example, many predatory animals hunt in pairs or larger groups, and this involves synchronized cooperation. 'Tit for tat' ha...

Scientists track chemical changes in cells as they endure extreme conditions

...ovides valuable clues to how it adapts. But, as Holman explains, scientists must also understand the ever-changing chemistry inside a cell in order to fully understand its gene expression and adaptive-response pathways. Scientists have also teased out the chemical changes in the bacterium by studying di...

First cGMP feeder-independent pluripotent stem cell banks released for distribution

...e variety of other cGMP lines, including lines produced from newly derived, fully compliant human ES cells and induced pluripotent stem (iPS) cells. These cl... cell properties, as well as cGMP working cell banks, derived from the same fully tested master cell bank under cGMP conditions. Derek Hei, director of th...

Robo-bats with metal muscles may be next generation of remote control flyers

... developing a "robo-bat" skeleton using rapid prototyping technologies. The fully assembled skeleton rests easily in the palm of your hand and, at less than ...we can control all of the variables and finally give us the opportunity to fully understand the aerodynamics of flapping flight," Seelecke says. ...

Double success for Instituto Gulbenkian de Ciencia scientists working on chromosome segregation

...ct. Moreover, entry into the EMBO Young Investigator Programme allows me to fully integrate our emerging laboratory in the larger European scientific communi...n the EMBC, the EMBO intergovernmental funding body and, as such, hosts and fully finances the grants awarded to scientists who wish to establish themselves ...

Ovarian transplantation: First baby is born after a new technique

...ritoneal areas three days before the real transplant. The first graft encourages the growth of blood vessels and paves the way for the ovary to become fully functioning in a shorter time scale than would be possible if all the tissue were to be transplanted at the same time. The researchers have so far ...

Female human embryos adjust the balance of X chromosomes before implantation

...res." This might mean that human embryonic stem cells could behave in a different and possibly unpredictable way to that expected. If they are not fully undifferentiated, then they might be unable to transform completely into the particular tissues that researchers might be trying to create in the labo...

Cells use import machinery to export their goods as well

...nding role in endocytosis -- clathrin, dynamin and actin. In the absence of any one of these molecules, the researchers found that the vesicles merged fully with the membrane and disgorged all their cargo, which they had shown was an aberration in exocytosis, not the rule, as had been previously assumed. T...

M2SYS Technology to Offer Desktop Biometric Technology to Kronos Customers

...SYS Technology, www.m2sys.com , is a recognized industry leader in biometric identity management technology, delivering a wide range of customized, fully functional, turn-key fingerprint, finger vein, and other biometric software solutions for businesses and consumers. About Kronos Kronos is t...

A Canada-wide technology platform for mapping the human interactome

...Dr. Coulombe. "I am proud that the IRCM is coordinating such an important Canada-wide initiative under the leaderschip of Dr. Coulombe. The IRCM is fully committed to provide all necessary support for the success of this new technology platform," added Dr. Tarik Mry, President and Scientific Director of...

Molecular typesetting -- proofreading without a proofreader

...is essential to the proper functioning of our bodies, but the 'quality assurance' mechanisms that take place during this manufacturing process are not fully understood. "Scientists have been puzzled as to how this process makes so few mistakes", says Dr Netta Cohen, Reader at the University of Leeds' Sc...

Policy transparency key to saving world's fisheries

... billion annually. This same report indicates that 28% of the world's fisheries stocks are currently being overexploited or have collapsed and 52% are fully exploited. "The consequences of overexploiting the world's fisheries are a concern not only for food security and socio-economic development but fo...

Leading scientists and scholars urge action on climate issues

...ustain the integrity of global climate and to hold the risk of ruinous climatic change to an acceptably low level. United States policy must provide a fully satisfactory U.S. contribution to global greenhouse gas reductions that move beyond these inadequate international limits." The letter's authors po...

Beaked, bird-like dinosaur tells story of finger evolution

...ilized mire pits. A close examination of the fossil shows that its upper and lower jaws were toothless, demonstrating that the dinosaur possessed a fully developed beak. Its lack of teeth, short arms without sharp claws and possession of gizzard stones suggest that it was a plant-eater, though it is rel...

They are young and need the job: A second chance for dangerous T-cells

...ate destiny. Young autoreactive T-cells are very readily reeducated into regulatory T-cells. Under identical conditions, however, older T-cells become fully activated and can cause damage they are in a way resistant to reeducation. "We now intend to study at the molecular level what makes a T-cell accessi...

American Chemical Society weekly presspac -- June 10, 2009

... researchers say. ARTICLE #4 FOR IMMEDIATE RELEASE "A Stably engineered, Suicidal Strain of Listeria monocytogenes Delivers Protein and/or DNA to fully Differentiated Intestinal Epithelial Monolayers" DOWNLOAD FULL TEXT ARTICLE: http://pubs.acs.org/stoken/presspac/presspac/full/10.1021/mp800153u ...

Dual role in breast tissue for a protein involved in leukemia

... be used as a drug target for leukemia or other cancers, it is important to fully understand how altering its function impacts the breast, especially since i...a little less differentiated than they should be, meaning that they are not fully developed enough to participate in milk production. Miermont found that whe...

Flexible solar strips light up campus bus shelter

...helter for the better part of a night. The solar cell research team is monitoring the installation to determine how much solar power is required to fully recharge the batteries based on weather conditions. Winter months will be a particular focus as shorter and overcast days, snow and cold can affect t...

UC Davis begins $2.8 million in studies of agricultural nitrogen's impacts

... water and leading to "dead zones" -- areas that cannot support finfish, shellfish or most other aquatic life. Those environmental impacts are not fully documented, Tomich said. "With this new funding, we can start to fill in those blanks, and improve management of nitrogen, carbon and water to help...
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