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REGiMMUNE presents enhanced efficacy data in preclinical transplantation models

Boston, MA June 1, 2009 REGiMMUNE Corporation today announced that its lead product candidate RGI-2001, in combination with a low-dose of Sirolimus, demonstrated enhanced efficacy in transplantation tolerance induction in models of skin transplantation and acute Graft-versus-Host disease (GvHD)....

Early isolation linked to enhanced response to cocaine

NEW ORLEANSDrug addiction affects millions of people around the world, causing numerous problems ranging from emotional and psychological difficulties to physical and health issues. Initial drug use can be motivated by curiosity or peer pressure, but in some animals, such as rats, it can also be t...

Early isolation linked to enhanced response to cocaine

NEW ORLEANSDrug addiction affects millions of people around the world, causing numerous problems ranging from emotional and psychological difficulties to physical and health issues. Initial drug use can be motivated by curiosity or peer pressure, but in some animals, such as rats, it can also be t...

Syntermed licenses Emory ERTb software for enhanced cardiac imaging

A comprehensive software package designed to significantly improve the quality and accessibility of nuclear cardiology images has been licensed by Emory University to Syntermed, an Atlanta-based nuclear medicine imaging and informatics software company. The software, called the Emory Reconstructi...

CrimeCog Technologies Unveils Enhanced JMS Module of E*JUSTICE SYSTEMS(TM)

Updates include additional automated financial functions, inmate billing and interfaces SACRAMENTO, Calif., May 5 /PRNewswire/ -- Today, at the American Jail Association Conference in Sacramento, CA, CrimeCog Technologies announced an enhanced version of its Jail Bo...

Penn researchers find monkeys able to fend off AIDS-like symptoms with enhanced HIV vaccine

(PHILADELPHIA) Researchers at the University of Pennsylvania School of Medicine have discovered that using an immune system gene to enhance a vaccine used to study HIV in macaque monkeys provides the animals with greater protection against simian HIV (SHIV) than an unmodified vaccine. This multi-...

Scientists genetically engineer tomatoes with enhanced folate content

Leafy greens and beans aren't the only foods that pack a punch of folate, the vitamin essential for a healthy start to pregnancy. Researchers now have used genetic engineering--manipulating an organism's genes--to make tomatoes with a full day's worth of the nutrient in a single serving. The scie...

Making mice with enhanced color vision

Researchers at the Johns Hopkins School of Medicine and their colleagues have found that mice simply expressing a human light receptor in addition to their own can acquire new color vision, a sign that the brain can adapt far more rapidly to new sensory information than anticipated. This work, a...

Fish growth changes enhanced by climate change

Changes in growth rates in some coastal and long-lived deep-ocean fish species in the south west Pacific are consistent with shifts in wind systems and water temperatures, according to new Australian research published in the United States this week. “We have drawn correlations between the growth...

Researchers report technique for freezing and preserving genetically enhanced pig embryos

Researchers led by a University of Missouri-Columbia professor of reproductive biotechnology have reported success in freezing and preserving swine embryos that were created by in vitro techniques and that carried modified genetic material. After thawing and transfer to a surrogate mother, some of ...

Study finds that nutritionally enhanced rice reduces iron deficiency

Breeding rice with higher levels of iron can have an important impact on reducing micronutrient malnutrition, according to a new study in the Journal of Nutrition. The research, conducted by scientists from the Philippines and the United States, is a major step forward in the battle against iron de...

Mouse with designer liver has enhanced glucose tolerance, insulin response

A collaborative effort led by The Burnham Institute's Gen-Sheng Feng has created a mouse with improved glucose tolerance and insulin activity in the liver, and generated new findings about insulin-signaling in the liver that could prove useful in understanding the pathogenesis of type 2 diabetes. T...

Scientists find universal rules for food-web stability

...shed in this week's issue of Science , conclude that food-web stability is enhanced when many diverse predator-prey links connect high and intermediate trophic...al universal rules in the dynamics of ecosystems. "Food-web stability is enhanced when species at high trophic levels feed on multiple prey species and speci...

Restoring a natural root signal helps to fight a major corn pest

...ae of the Western corn rootworm, a voracious root pest. In field tests, the enhanced nematode attraction resulted in reduced root damage and considerably fewer ... "Our study showed that the re-established natural EβC signal greatly enhanced the effectiveness of nematodes in controlling Western corn rootworm", Hiltp...

August 2009 Geology and GSA Today media highlights

...chnology for mapping areas that may contain NOA include locating roads that are surfaced with serpentine aggregate, identifying sites that may require enhanced dust control or other safety measures, and filling gaps in geologic mapping where field access is limited. GEOLOGY abstracts are available for revi...

Iron isotopes as a tool in oceanography

...ating processes. "In the future I would like to examine processes of sedimentary iron cycling in the high-latitudes, where sediments are subject to enhanced rates of environmental change due to changing climate in these regions," Said Homoky. ...

Nanodiamonds deliver insulin for wound healing

... was released from the nanodiamond clusters and retained its function. Exploiting this pH-mediated release mechanism may provide unique advantages for enhanced drug delivery methods. The researchers also found the insulin slowly and consistently released from the nanodiamond clusters over a period of sever...

DOE-funded research projects win 46 R&D 100 Awards for 2009

... capabilities of multicore processors to deliver significant improvements in data access performance for parallel computing applications. CNW provides enhanced data access capabilities beyond other equivalent operating systems by employing a new technique that targets memory bandwidth. NanoCoral Dendritic...

Improved air quality during Beijing Olympics could inform pollution-curbing policies

...ropean Union regulations. A similar standard was mandated starting in June 2008 for 20,000 buses and 66,000 taxies. The improved fuel quality probably enhanced the performance of engines and catalytic converters, the researchers reported. "We are showing what the city can do if they are determined to impro...

UC San Diego's $3 million NSF grant to fund science festivals

... purpose of establishing year-round Science Festival Educational Enrichment activities for students of all ages across San Diego. Each annual cycle of enhanced science education programs will both open and close with the week-long celebration of science and technology in conjunction with local science and res...

University of Minnesota research leads to new technology to protect human health

... protein by the most common chemical assay used to test for food protein. This has led to a practice of adding melamine to any food where its value is enhanced by increasing the apparent protein content. For example, melamine-tainted pet food killed nearly 1,000 U.S. pets during one episode in 2007. ...

Reviews of microbial gene language published in special issue of Trends in Microbiology

...emes in the delivery of effector molecules by different microbes. Our understanding of the key steps in host-microbe interactions will be considerably enhanced by the further widespread use of Gene Ontology terms, which should in turn generate proposals for more terms." Another review reveals how terms cre...

$29.4 million grant establishes CTSI at NYU in partnership with Health and Hospitals Corporation

... diversity of HHC." "NYU School of Medical and HHC have come together to establish the CTSI for the purpose of redefining clinical research through enhanced collaborations of research and clinical teams," said Alan D. Aviles, president of NYC Health and Hospitals Corporation. "Together our institutions ha...

A 'heart healthy' diet and ongoing, moderate physical activity may protect against cognitive decline

...ling or swimming; mental status test scores; and APOE genotype. In their analysis, the researchers found that physical activity was associated with enhanced cognitive function, and that this relationship was differentially influenced by the person's APOE genotype: non-E4 carriers and people with one copy o...

ACS Technologies(TM) Selects M2SYS for Innovative Biometric Software

...es in demand for biometric technology with faith-based organizations as they start to understand the benefits, including improved attendance tracking, enhanced security, and the elimination of passwords and PIN numbers. Because no image of the fingerprint is stored, their security fears are also being diminis...

New technique can fast-track better ionic liquids for biomass pre-treatments

...lubilization and fractionation of either polysaccharides or lignin could be tailored for the development of cost-effective biomass pre-treatments with enhanced yields of sugars." The ultimate goal, Simmons says is to find an ionic liquid that can efficiently pre-treat biomass, then scale its use up into a ...

22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey

...ed dramatically. Advances in brain imaging, the mapping of the brains biochemical circuitry and breakthroughs in molecular genetics have significantly enhanced the possibilities of the neurosciences. These advances have given physicians and scientists greater insight into the brain. Today neural activity in n...

Scientists closer to developing salt-tolerant crops

... the amount of toxic Na+ building up in the shoot and so increases the plant's tolerance to salinity," Professor Tester says. "In doing this, we've enhanced a process used naturally by plants to minimize the movement of Na+ to the shoot. We've used genetic modification to amplify the process, helping plan...

Frost & Sullivan Looks at Biometrics Advancement in Civil Security: Exploring Opportunities for Today and Beyond

...ct and detect potential terrorist threats and criminal activities, rather than responding to attacks. The success of biometric technology in providing enhanced security with accuracy and efficiency has prompted the biometric industry to focus more on research and development and the civil security industry is...

Pitt team finds molecule that regulates heart size by using zebrafish screening model

...gnaling. They then figured out how: BCI blocked the activity of an enzyme called Dusp6, a feedback regulator that would otherwise have tamped down the enhanced FGF signal. Knowing that, BCI could then be used as a tool to find out what effect Dusp6 inhibition would have on heart development. Zebrafish tre...

Tryptophan deficiency may underlie quinine side effects

...ould be especially at risk to this drug. The authors also note that tryptophan is important as a precursor for the brain chemical serotonin, so the enhanced tryptophan deficiency induced by quinine could explain why many of quinine's side effects are localized to the head region. They also note that side-e...

High carbon dioxide levels cause abnormally large fish ear bones

...s, such as determining whether the otolith growth abnormality exists in fish other than white seabass; locating the physical mechanism that causes the enhanced otolith growth; and assessing whether the larger otoliths have a functional effect on the survival and the behavior of the fish. "Number three is ...

MicroRNAs help control HIV life cycle

...ve our ability to eliminate it." Rana's team looked at miR29 expression levels in infected and uninfected cells and found that miR29 expression was enhanced by HIV-1 infection. Blocking the activity of miR29 with interfering RNA resulted in increased replication and infectivity of the virus. The scientists...

New nanoparticles could revolutionize therapeutic drug discovery

...d rapidly used for virtually any laboratory analysis. Advantages of SMALPs over traditional ways to solubilise proteins such as detergents include enhanced stability, activity and spectral quality of the protein membranes. Dr Tim Dafforn who jointly ran the study, said: "In the past, studies have conce...

Europe and China watching Earth together

...r both partners. Zhang Guocheng, Director-General of the National Remote Sensing Centre of China (NRSCC) said: "The Dragon 2 programme has greatly enhanced EO capabilities within China and has cultivated an extensive team of young scientists working in remote sensing for China." ESA's Dr Stephen Briggs...

Research explores interactions between nanomaterials, biological systems

... The recent explosion in the development of nanomaterials with enhanced performance characteristics for use in commercial and medical applications has increased the likelihood of people coming into direct contact with thes...

Protecting the food crops of the future

...comes from flowering plants - even the food that is fed to livestock. This means that the long-term future of the world's food supply would be greatly enhanced if we could predict and control flowering. Farmers need to be able to plan when their crops should be harvested and so our study has major significanc...

Versartis presents positive preclinical data on 2 product candidates at ENDO 09

... Washington, DC June 10, 2009 Versartis, Inc., an emerging company developing novel biologics with enhanced properties for patients with metabolic diseases, today presented data for its long-acting product candidates, VRS-317 (hGH-rPEG) for treatment of grow...

Beetle shell inspires brilliant white paper

...w shown that through careful mineral selection and processing, it is possible to mimic some of the structure of the white beetle's shell to produce an enhanced bright white coating for paper. This higher performance could result in lighter weight paper with a very high degree of whiteness. Lighter paper would...

Colon cancer screening technique shows continued promise in new study

... potentially be as or more successful than a colonoscopy in screening for colon cancer. The technique uses optical technology, called low-coherence enhanced backscattering (LEBS) spectroscopy, to analyze tissue samples taken from the base of the rectum. Light shines on the tissue, scatters, and some of tha...
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