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Embryonic in Biological News

Skin-like tissue developed from human embryonic stem cells

BOSTON (July 21, 2009) Dental and tissue engineering researchers at Tufts University School of Dental Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts have harnessed the pluripotency of human embryonic stem cells (hESC) to generate complex, multilayer tissues that mimic hu...

WARF signs license agreement with Pfizer for human embryonic stem cells

MADISON Pfizer Inc., a major biopharmaceutical company, and the Wisconsin Alumni Research Foundation (WARF), the private, nonprofit patenting and licensing organization for the University of Wisconsin-Madison, announced May 5 that they have signed a license for human embryonic stem (hES) cell pat...

Hebrew University researchers neutralize tumor growth in embryonic stem cell therapy

Jerusalem, May 5, 2009 Researchers at the Hebrew University of Jerusalem have discovered a method to potentially eliminate the tumor-risk factor in utilizing human embryonic stem cells. Their work paves the way for further progress in the promising field of stem cell therapy. Human embryonic ...

Scientists shed light on inner workings of human embryonic stem cells

(Santa Barbara, Calif.) Scientists at UC Santa Barbara have made a significant discovery in understanding the way human embryonic stem cells function. They explain nature's way of controlling whether these cells will renew, or will transform to become part of an ear, a liver, or any other part...

Study finds blood cells can be reprogrammed to act as embryonic stem cells

(WASHINGTON, April 20, 2009) - In a recent study, U.S. researchers have reprogrammed cells found in circulating blood into cells that are molecularly and functionally indistinguishable from embryonic stem cells, a revolutionary achievement that provides a readily accessible source of stem cells an...

Protein is key to embryonic stem cell differentiation

LA JOLLA, Calif., March 18, 2009 -- Investigators at Burnham Institute for Medical Research (Burnham) have learned that a protein called Shp2 plays a critical role in the pathways that control decisions for differentiation or self-renewal in both human embryonic stem cells (hESCs) and mouse embryo...

Director of Berman Institute comments on FDA Approval of first human embryonic stem cell trial

"The report today that the FDA has approved the first human clinical trial of an embryonic stem cell-based intervention raises important ethical considerations, but not only, or even primarily, because what is at issue is an embryonic stem cell-based intervention. Although deep-seated disagreemen...

Recipe for capturing authentic embryonic stem cells may apply to any mammal, study suggests

Researchers have what they think may be a basic recipe for capturing and maintaining indefinitely the most fundamental of embryonic stem cells from essentially any mammal, including cows, pigs and even humans. Two new studies reported in the December 26th issue of the journal Cell , a Cell Press ...

VistaGen, WARF sign license agreement for human embryonic stem cell technology

MADISON, VistaGen Therapeutics and the Wisconsin Alumni Research Foundation (WARF) have signed a license for human embryonic stem cell patents for the development and commercialization of stem cell-based research tools. VistaGen, a biotechnology company based in South San Francisco, is one of ...

Single virus used to convert adult cells to embryonic stem cell-like cells

CAMBRIDGE, Mass. (Dec. 15, 2008) Whitehead Institute researchers have greatly simplified the creation of so-called induced pluripotent stem (iPS) cells, cutting the number of viruses used in the reprogramming process from four to one. Scientists hope that these embryonic stem-cell-like cells coul...

Female embryonic sexual development driven by universal factor

A gene essential to the growth and development of most organ systems in the body also is vital to female but not male embryonic sexual development, scientists report this month. The study, from researchers at the University of Illinois and the University of Texas, appears in Human Molecular ...

Forsyth scientists trigger cancer-like response from embryonic stem cells

Boston--Scientists from The Forsyth Institute, working with collaborators at Tufts and Tuebingen Universities, have discovered a new control over embryonic stem cells' behavior. The researchers disrupted a natural bioelectrical mechanism within frog embryonic stem cells and trigged a cancer-like r...

Human embryonic stem cell secretions minimized tissue injury after heart attack

A novel way to improve survival and recovery rate after a heart attack was reported in the journal Stem Cell Research by scientists at Singapore's Institute of Medical Biology (IMB) and Bioprocessing Technology Institute (BTI) and The Netherlands' University Medical Center Utrecht. This meth...

Human embryonic stem cells developed from 4-cell embryo; world first may lessen ethical concerns

This release is available in Spanish . Barcelona, Spain: For the first time in the world scientists have succeeded in developing human embryonic stem cells (hESCs) from a single cell, or blastomere, of a 4-cell stage embryo, the 24th annual conference of the European Society of Human Reprod...

Wealth of genomic hotspots discovered in embryonic stem cells

In a paper published in Cell on June 13, 2008, Singapore scientists at the Genome Institute of Singapore (GIS) and the National University of Singapore (NUS) unveil an atlas that showing the location of "genomic hotspots" of essential protein "switches" (transcription factors) that are critical ...

Controlling embryonic fate by association

Association determines fate in embryonic stem cells, said Baylor College of Medicine researchers in a report that appears in the current issue of the journal Nature Cell Biology. These findings provide models of how the embryonic stem cell is maintained in its flexible state, said Dr. Zhou Song...

Protein protects embryonic stem cells' versatility and self-renewal

HOUSTON A protein known as REST blocks the expression of a microRNA that prevents embryonic stem cells from reproducing themselves and causes them to differentiate into specific cell types, scientists at The University of Texas M. D. Anderson Cancer Center report in the journal Nature. Resear...

Implanting embryonic cardiac cells prevents arrhythmias

When researchers at Cornell, the University of Bonn and the University of Pittsburgh transplanted living embryonic heart cells into cardiac tissue of mice that had suffered heart attacks, the mice became resistant to cardiac arrhythmias, thereby avoiding one of the most dangerous and fatal consequ...

Human embryonic stem cell -- derived bone tissue closes massive skull injury

There are mice in Baltimore whose skulls were made whole again by bone tissue grown from human embryonic stem cells (hESCs). Healing critical-size defects (defects that would not otherwise heal on their own) in intramembraneous bone, the flat bone type that forms the skull, is a vivid demonstr...

Oosight microscope enables embryonic stem cell breakthrough

MBL, WOODS HOLE, MA A noninvasive, polarized light microscope invented at the Marine Biological Laboratory (MBL) played a crucial role in a recent breakthrough in embryonic stem-cell research aimed at developing medical therapies. A team led by Shoukhrat Mitalipov, Ph.D., of Oregon Health & Sc...

Simple recipe turns human skin cells into embryonic stem cell-like cells

A simple recipeincluding just four ingredientscan transform adult human skin cells into cells that resemble embryonic stem cells, researchers report in an immediate early publication of the journal Cell, a publication of Cell Press. The converted cells have many of the physical, growth and genetic...

Researchers discover important tool in understanding differentiation in human embryonic stem cells

Researchers at the University of Minnesotas Stem Cell Institute have described how an existing genetic tool can be used to study how human embryonic stem cells differentiate. The research appears in the November 2007 issue of Experimental Biology and Medicine. Researchers know very little about...

From GM farm animals to embryonic stem cell research

Genomics and Society: Todays Answers, Tomorrows Questions taking place in London on Thursday 25 and Friday 26 October 2007 - brings together policymakers, researchers and natural scientists with what is becoming the worlds largest concentration of social scientific research in the field of genomi...

Human embryonic stem cells remain embryonic because of epigenetic factors

A human embryonic stem cell is reined in prevented from giving up its unique characteristics of self-renewal and pluripotency by the presence of a protein modification that stifles any genes that would prematurely instruct the cell to develop into heart or other specialized tissue. But, thanks t...

Scientists identify embryonic stem cells by appearance alone

CAMBRIDGE, Mass. (August 27, 2007) Some scientific results are hard to spot, especially in genetic research. Often scientists are unable to physically see if the gene they inserted into a cell has produced the desired trait. To overcome this problem researchers use various genetic markers that c...

Left-right wiring determined by neural communication in the embryonic worm

Most animals appear symmetrical at first glance, but we're full of internal lop-sidedness. From the hand used to pick up a pencil or throw a baseball, to where language is generated in the brain, to the orientation of our internal organs, humans are a glut of asymmetries. Worms aren't so different:...

Scientists discover stage at which an embryonic cell is fated to become a stem cell

Cambridge scientists have discovered the stage at which some of the cells of a fertilised mammalian egg are fated to develop into stem cells and why this occurs. The findings of the study, which overturn the long-held belief that cells are the same until the fourth cleavage (division) of the embry...

Scientists unlock mystery of embryonic stem cell signaling pathway

A newly discovered small molecule called IQ-1 plays a key role in preventing embryonic stem cells from differentiating into one or more specific cell types, allowing them to instead continue growing and dividing indefinitely, according to research performed by a team of scientists who have recently...

Vaccination with embryonic stem cells prevents lung cancer in mice

Researchers in America have discovered that vaccinating mice with embryonic stem cells prevented lung cancer in those animals that had had cancer cells transplanted into them after the vaccination or that had been exposed to cancer-causing chemicals. The findings suggest that it could be possib...

Stem cells found in adult hair follicles may provide alternative to embryonic stem cells

Having recently identified the molecular signature of these epidermal neural crest stem cells in the mouse, their research resolves conflicting scientific opinions by showing that these cells are distinctly different from other types of skin-resident stem cells/progenitors. Their work provides a v...

Researchers create genetically matched embryonic stem cells for transplantation

Researchers at Children's Hospital Boston report a new and efficient strategy, using eggs alone, for creating mouse embryonic stem cells that can be transplanted without the risk of rejection because the cells are compatible with the recipient's immune system. The findings will be published online ...

UCLA researchers develop T-cells from human embryonic stem cells

Researchers from the UCLA AIDS Institute and the Institute for Stem Cell Biology and Medicine have demonstrated for the first time that human embryonic stem cells can be genetically manipulated and coaxed to develop into mature T-cells, raising hopes for a gene therapy to combat AIDS. The study, ...

Sperm created in the laboratory from embryonic stem cells produce viable progeny

Scientists have demonstrated for the first time that embryonic stem (ES) cells cultured in the laboratory can produce sperm with the capacity to produce viable offspring. The research, published in the July issue of Developmental Cell, opens many exciting avenues for future studies, including inves...

With few factors, adult cells take on character of embryonic stem cells

With the introduction of just four factors, researchers have successfully induced differentiated cells taken from mouse embryos or adult mice to behave like embryonic stem cells. The researchers reported their findings in an immediate early publication of the journal Cell. The cells--which the r...

Neurons grown from embryonic stem cells restore function in paralyzed rats

For the first time, researchers have enticed transplants of embryonic stem cell-derived motor neurons in the spinal cord to connect with muscles and partially restore function in paralyzed animals. The study suggests that similar techniques may be useful for treating such disorders as spinal cord i...

With few factors, adult cells take on character of embryonic stem cells

With the introduction of just four factors, researchers have successfully induced differentiated cells taken from mouse embryos or adult mice to behave like embryonic stem cells. The researchers reported their findings in an immediate early publication of the journal Cell, published by Cell Press. ...

Liquid crystals show promise in controlling embryonic stem cells

Liquid crystals, the same phase-shifting materials used to display information on cell phones, monitors and other electronic equipment, can also be used to report in real time on the differentiation of embryonic stem cells. Differentiation is the process by which embryonic stem cells gradually t...

Novel molecular 'signature' marks DNA of embryonic stem cells

A team of scientists announced today a critical step on the path of realizing the promise of embryonic stem (ES) cells for medicine. As described in the April 21 issue of Cell, the researchers have discovered unique molecular imprints coupled to DNA in mouse ES cells that help explain the cells' ra...

UCI researchers discover key factor for survival of human embryonic stem cells

Human embryonic stem cells (hES) offer great hope for the treatment of some devastating diseases, but finding a way to keep enough of these cells usable and healthy for transplantation in patients has been an ongoing problem. Now scientists at UC Irvine have discovered a way to keep large quantitie...

Human prostate grown from embryonic stem cells

In a giant step towards understanding prostate disease, Melbourne scientists have grown a human prostate from embryonic stem cells. A study published in the March edition of Nature Methods describes how human embryonic stem cells were developed into human prostate tissue equivalent to that found ...
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