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Donor in Biological News

Children born after donor insemination should be told as soon as possible about their conception

Barcelona, Spain: It is better for children conceived by donor insemination to be told of their origins at an early age, according to the first large-scale study of people who are aware of their donor conception. If the children are not told until they are 18 or older, they are more likely to have...

US woman gives birth to baby from world's first frozen donor egg bank

(Lexington, Kentucky, USA, 1/2/06) Wendy and Jared Kennedy are thrilled with their New Year baby girl, Avery Lee, born December 31, 2005, at the University of Kentucky Chandler Medical Center in Lexington, Kentucky. They are the first couple to deliver a baby from the first commercial donor egg ba...

UK sperm donor crisis

A study by a leading UK fertility centre has found that the numbers of men ?especially students ?coming forward as potential sperm donors fell sharply after 2000, almost certainly due to growing awareness that changes in the law would be removing the right to anonymity. The fall in applications, ...

World-first Living Donor Islet Cell Transplant A Success; Procedure Offers Promise For Diabetics

A University of Alberta and Capital Health surgeon, well known for his pioneering work in developing the Edmonton Protocol treatment for diabetes, has taken another important step in the fight against diabetes. On January 19, at Kyoto University Hospital, Dr. Koichi Tanaka and Dr. James Shapiro,...

First human gets new antibody aimed at hepatitis C virus

...gics is designed to be a therapy shortly before and after transplant surgery. By giving a patient the new antibody before and during the time when the donor liver is implanted, researchers hope the HCV virus left in the bloodstream will be neutralized and rendered unable to infect the new liver. Then, beca...

Children's Hospital Oakland scientists first to discover new source for harvesting stem cells

...m umbilical cord blood, Children's Hospital Oakland physicians have cured more than 100 kids with chronic blood-related diseases through their sibling donor cord blood transplantation program, which began in 1997. However, according to the American Cancer Society, each year at least 16,000 people with seri...

Adult bone marrow stem cells injected into skeletal muscle can repair heart tissue

.... This advance has lead to another health hurdle: The only therapy available to reverse the decline in cardiac function is heart transplantation, and donor hearts are very scarce. Clinical trials of myocardial stem cell therapy traditionally have relied on surgery -- infusing the stem cells directly int...

American Chemical Society's Weekly PressPac -- May 13, 2009

...cs. They also found that freshly collected platelets from diabetics show almost as many abnormal changes (more than 100) in protein content as healthy donor platelets stored for up to 5 days. These findings could lead to new tests for detecting and monitoring abnormal platelets to improve the outcome of bl...

Novel antibody prevents infection by hepatitis C virus

... MBL is designed to be a therapy shortly before and after transplant surgery. By giving a patient the new antibody before and during the time when the donor liver is implanted, researchers hope the HCV virus left in the bloodstream will be neutralized and rendered unable to infect the new liver. Then, beca...

World premiere in stem cell research in Montreal

...f it were an invader. By extrapolation from laboratory studies, it is very likely that transplanting hematopoietic stem cells collected from the organ donor and developed in the laboratory could avoid rejection of this organ. This is why it is important to have large quantities of hematopoietic stem cells,...

Stem cell therapy makes cloudy corneas clear, according to Pitt researchers

...cess rate, but they don't last forever. The current popularity of LASIK corrective eye surgery is expected to substantially reduce the availability of donor tissue because the procedure alters the cornea in a way that makes it unsuitable for transplantation." A few years ago, Dr. Funderburgh and other U...

Amniotic fluid may provide new source of stem cells for future therapies

...etic organs examined after 10-13 weeks. The secondary transplants with mouse AFKL cells were partially successful with some of the mice engrafting the donor cells. This finding shows that AFKL cells have the ability to self-renew, a key characteristic of stem cells. Though the human AFKL cells failed to...

Therapeutic cloning gets a boost with new research findings

...ates, however, adult somatic cells are used as the donor cells in a cloning process called somatic cell nuc...clear transfer, only one adult somatic cell -- one donor cell -- is needed," he explains. "Because a rando...eneck effect limits the transfer of mutations from donor cells to cloned offspring." Not only did the re...

Flight of the bumble (and honey) bee

...l in both directions (east and west) down the row from the central block of donor plants, results also indicate that significant movement also occurred across rows in both directions (north and south) from the donor plot", he remarked. Because watermelon vines grow in multiple directions...

Spun-sugar fibers spawn sweet technique for nerve repair

...r part of the body to repair the injured nerves. Researchers are trying to develop artificial scaffolds to replace the autografts because removing the donor nerve causes a lack of sensation in the portion of the body where it was removed. "The autograft is the lesser of two evils because you have to sac...

Caltech and UCSD researchers shed light on how proteins find their shapes

...osecond camera that captures fluorescent flashes as a laser pulse excites a donor probe, which emits light and transfers that light to an acceptor probe. The distance between the donor and acceptor change as the amino-acid chain transforms itself into a three-...

Patience pays off with methanol for uranium bioremediation

...ediation in a study funded by the Department of Energy's Environmental Remediation Sciences Program. Madden et al. report that the particular electron donor chosen affects not only the rate of uranium removal from solution, but also the extent of U6+ conversion to U4+. Results of the study were published i...

Shorter wait means longer life for kidney transplant candidates

...activity and other factors. The longer a person waits, the more dialysis he or she gets, and the poorer the life expectancy. Long waiting times for donor organs have led many people to seek alternatives, some of which have raised ethics questions. One example in the United States is a members-only organ...

Advancement in tissue engineering promotes oral wound healing

...ty include bulkiness, sweating and hair formation and the limited amount of donor tissue available." Their current study was aimed at constructing analogo...e future. "This study emphasized the importance of closely matching the donor site with the area to be transplanted," said Dr. Gibbs. "Our results repres...

Animal eggs not suitable substitutes to produce stem cells

...or therapeutic applications. The shortage of human donor eggs has led to efforts to substitute animal oocyt... on, or up-regulate a large number of genes in the donor nucleus. Although previous reports have docum...re have been no data indicating to what extent the donor human DNA was reprogrammed. Lanza et al. show for...

Human beta cells can be easily induced to replicate, according to study in Diabetes

...ld allow more effective therapeutic transplants of insulin-producing cells either by expanding the numbers of cells available from a single cadaveric donor or from a gene-enhanced version of the patient's own cells, or by establishing permanent cell lines from existing beta cells or stem cells, Dr. Stewar...

American Chemical Society's Weekly PressPac -- Dec. 17, 2008

...rounds offer new source of biodiesel fuel Better antifreezes to preserve donor organs for transplantation Producing a more effective oral form of a po... ARTICLE #3 FOR IMMEDIATE RELEASE Better antifreezes to preserve donor organs for transplantation Journal of the American Chemical Society ...

Sulfurous ping-pong in the urinary tract

...the function of ASST. They built a reaction cage that accommodates both the donor and the acceptor of the sulfuryl group. Furthermore, during the transfer, t...istidine side chain of ASST. Thus, the signal is first transferred from the donor to ASST and subsequently from ASST to the acceptor. Such a ping-pong mechan...

New 'control knobs' for stem cells identified

... Tufts researchers studied the changes in membrane potential (voltage across the membrane) shown by human mesenchymal stem cells (hMSCs) obtained from donor bone marrow as the hMSCs were differentiating into fat and bone cells. They found that hyperpolarization (increased difference between the voltage in ...

Researcher tricks immune system in diabetic mice

...1 diabetes undergo human islet cell transplantation. The islet cells from a donor pancreas produce robust amounts of insulin for the recipient -- often permi...ter they had islet transplantation. "We made the recipient feel that the donor cells are their own," explained Stephen Miller, co-principal investigator a...

New technique eliminates toxic drugs in islet transplant in diabetic mice

...1 diabetes undergo human islet cell transplantation. The islet cells from a donor pancreas produce robust amounts of insulin for the recipient -- often permi...ter they had islet transplantation. "We made the recipient feel that the donor cells are their own," explained Stephen Miller, co-principal investigator a...

Major conference on food Dec. 1-2, 2008

... The world's largest alliance on agricultural research will convene more than 700 leading food and environmental scientists, policy makers and donor representatives in Maputo, Mozambique, on 1-2 December 2008 to discuss the best approaches for meeting the food needs of the poor in Africa. Four cr...

Adult stem cell breakthrough

...al segment was donated by a 51-year-old transplant donor who had who had died of cerebral haemorrhage. Spai...s decellularised over a six-week period so that no donor cells remained. Stem cells were obtained from t...ony Hollander at the University of Bristol. The donor trachea was then seeded with chondrocytes on the o...

Intraspinal implant of mesenchymal stem cells may not heal the demyelinated spinal cord

...urther experimentation with directly implanted MSCs is still called for since a variety of other MSC populations, such as autologous cells whereby the donor and recipient are the same organism, have been used in experimental and clinical settings with some degree of success. "Our results contrast with pr...

USAID grant awarded to improve food security in Africa

..., Education, and Development. "Through our past success in international agricultural research, we have built a good reputation both overseas and with donor agencies. In this time of rising food prices worldwide, I'm honored that we've been selected to manage this critically important project." ...

Heart valves that grow with the patient

...lleagues, on the other hand, use heart valves that are "grown" from the young patient's natural body cells. To do this, a valve from a human or animal donor is removed of all cells using tissue engineering, so that only its outer framework remains. This valve matrix is then colonised with cells that have b...

Embryonic stem cells might help reduce transplantation rejection

...nvolves taking embryonic stem cells with the same genetic background as the donor from which the organ or bone marrow ultimately will come and adapting them ...avazava explained. "When we then transplanted into the recipient mouse a donor mouse heart that had the same genetic make-up as the previously injected st...

Prosthetic vein valve designed to direct blood flow shows promising pre-clinical results

...ith a prosthetic one is likely the better option because finding a suitable donor valve in one of the patient's legs can be difficult, according to Ku. "Previous studies have shown that even if a donor valve is found, implanting it can cause significant trauma to the patient's...

Battling diabetes with beta cells

...iled to multiply mouse beta cells in culture, Prof. Efrat's work has increased the number of human beta cells successfully. "In theory, cells from one donor can be multiplied thousands of times," says Prof. Efrat, explaining that the next hurdle will be to "convince" these beta cells to produce insulin in ...

Children's national co-leads nationwide study of landmark sickle cell treatment

...air for a new national clinical trial of unrelated donor marrow and umbilical cord blood transplants for se...percent of severe sickle cell cases have a matched donor within their family. Successful transplants using ...study. "Preliminary results from the few unrelated donor transplants that have been performed for other non...

Energy industry leaders commit $1.6M to UH petroleum program

...Marathon's funds are unrestricted and will be used to address the most pressing needs of the new degree program as it develops. The company has been a donor to UH since 1989, with previous giving totaling nearly $400,000. "We applaud the formation of the petroleum engineering program at the University o...

American Chemical Society's Weekly PressPac -- July 16, 2008

...s to survive frigid winter temperatures. Their laboratory-produced first-of-a-kind proteins could have practical uses in extending the storage life of donor organs and tissues for human transplantation, the researchers indicate in a report scheduled for the July 9 issue of the Journal of the American Chem...

Standards in stem cell research

.... However each human embryonic stem cell holds the genetic signature of the donor which differs between donors just as people themselves differ. Further the ...dising the materials of stem cell production when other differences such as donor history and derivation methods are so complex, manifold and, to date, large...

Researchers discover link between organ transplantation and increased cancer risk

...th of these cases, a patient's pre-transplant immune system might have kept these cancers in check or cancer-causing viruses could have come from the donor organ. Physicians have long observed that immunosuppressive agents, such as the class of calcineurin inhibitors that includes cyclosporine, appear to ...

New studies predict record land grab as demand soars for new sources of food, energy and wood fiber

...loitation, compared to 1.6 Mha of forest land legally designated for use by communities. The RRI studies call for a number of recommendations that donor nations, agencies and advocacy organisations can implement to strengthen rights and to ensure that indigenous and local forest communities participate...
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