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Scientists open doors to diagnosis of emphysema

Chronic inflammatory lung diseases like chronic bronchitis and emphysema are a major global health problem, and the fourth leading cause of death and disability in developed countries, with smoking accounting for 90% of the risk for developing them. Work by scientists at the European Molecular Bio...

Preimplantation genetic diagnosis may pose neurological risks

Preimplantation genetic diagnosis (PGD) has helped many couples conceive healthy children and is generally considered a safe practice. However, a new long-term analysis of PGD in mice suggests that this procedure may increase risks of weight gain and memory decline in adulthood. PGD is used al...

UC Davis grant zeroes in on novel asthma diagnosis and treatment

DAVIS--An entomology professor at the University of California, Davis who discovered a novel therapeutic target for treating inflammation, has received a three-year $750,000 grant from the American Asthma Foundation to investigate whether his discovery will work on asthma, a chronic disea...

Muscular dystrophy diagnosis delayed almost 2.5 years in boys

Boys show signs of Duchenne Muscular Dystrophy (DMD) for 2 years before they obtain a diagnosis and disease-specific treatment, about the same length of delay children have endured for the past 20 years despite advances in genetic testing and treatment. A simple and inexpensive blood test for any...

A London effort to develop point-of-care nanosensors for HIV diagnosis and monitoring

The London Centre for Nanotechnology will develop a new device to enable people living with HIV to monitor their own health and the effectiveness of their treatments, thanks to a 2 million EPSRC (Engineering and Physical Sciences Research Council) grant announced today. The device will give peo...

Molecular fingerprints point the way to earlier cancer diagnosis and more targeted treatment

AUGUSTA, Ga. Metabolites are molecular fingerprints of what your cells are up to and Dr. Arun Sreekumar wants to know the impression made by cancer. You've likely heard about metabolites; your physician probably screens for some known ones such as triglycerides or cholesterol at your annual ph...

Einstein and Pitt researchers develop new TB test that will dramatically cut diagnosis time

March 19, 2009 (BRONX, NY) Researchers from the Albert Einstein College of Medicine and The University of Pittsburgh have developed an onsite method to quickly diagnose tuberculosis (TB) and expose the deadly drug-resistant strains that can mingle undetected with treatable TB strains. This stud...

New discovery paves the way for new diagnosis of serious lung disease

The discovery by Uppsala University researchers of a previously unknown protein in the cells of the lower air ways brings new potential for early diagnosis of a serious lung disease. The findings, published today in the Web edition of the American journal Proceedings of the National Academy of S...

New research findings may enable earlier diagnosis of uterine cancer

Cancer is a genetic disease. It occurs when changes take place in the genes that regulate cell division, cell growth, cell death, cell signalling and blood vessel formation either due to mutations caused by external factors such as smoking or radiation or due to inherited changes. This interacti...

Multiple Sclerosis: new MRI contrast medium enables early diagnosis in animal model

In an animal model of multiple sclerosis (MS), neuroradiologists and neurologists of the University hospitals of Heidelberg and Wrzburg have been able to visualize inflammatory tissue damage, most of which had remained unrecognized up to now, with the aid of a new contrast medium, Gadofluorine M, ...

ASM and FIND to partner on strengthening infectious disease diagnosis in developing nations

The American Society for Microbiology (ASM) and the Foundation for Innovative New Diagnostics (FIND) have signed a Memorandum of Understanding today confirming their agreement to work in partnership for projects aimed at strengthening infectious disease diagnosis and service integration in resourc...

ETH Zurich and IBM improve diagnosis of osteoporosis

With the goal of developing an accurate, powerful and fast method to automate the analysis of bone strength, scientists of the ETH Zurich Departments of Mechanical and Process Engineering and Computer Science teamed up with supercomputing experts at IBM's Zurich Research Laboratory. The breakthro...

60 second test could help early diagnosis of common brain diseases

Until recently physicians have had to rely on time-consuming and uncertain behavioural examinations to diagnose the onset of brain diseases such as multiple sclerosis, Alzheimer's and schizophrenia. Research published next week in the Institute of Physics' Journal of Neural Engineering suggests ...

Newly discovered gene fusion may lead to improved prostate cancer diagnosis

Researchers from NewYork-Presbyterian Hospital/Weill Cornell Medical Center have discovered a new gene fusion that is highly expressed in a subset of prostate cancers. The results may lead to more accurate prostate cancer testing and new targets for potential treatments. Experts believe that gene ...

Faster, more cost-effective DNA test for crime scenes, disease diagnosis

Scientists in Japan are reporting development of a faster, less expensive version of the fabled polymerase chain reaction (PCR) a DNA test widely used in criminal investigations, disease diagnosis, biological research and other applications. The new method could lead to expanded use of PCR in medi...

Study shows California's autism increase not due to better counting, diagnosis

(SACRAMENTO, Calif.) A study by researchers at the UC Davis M.I.N.D. Institute has found that the seven- to eight-fold increase in the number children born in California with autism since 1990 cannot be explained by either changes in how the condition is diagnosed or counted and the trend shows ...

Attitudes towards assisted reproduction and preimplantation genetic diagnosis

Madrid, December 15, 2008.- According to an international survey by the BBVA Foundation conducted this year, citizens in advanced societies view assisted reproduction techniques in general and in vitro fertilization in particular as firmly acceptable alternatives for people with fertility problems...

Microarray analysis improves prenatal diagnosis

HOUSTON -- (Nov. 17, 2008) -- A "chip" or array that can quickly detect disorders such as Down syndrome or other diseases associated with chromosomal abnormalities proved an effective tool in prenatal diagnosis in a series of 300 cases at Baylor College of Medicine, said researchers in a report th...

'Addicted' cells provide early cancer diagnosis

Scientists at the Institute of Food Research have detected subtle changes that may make the bowel more vulnerable to the development of tumours. With support from the Food Standards Agency and the Biotechnology and Biological Sciences Research Council they are investigating whether diet could ...

New technique can be breakthrough for early cancer diagnosis

Early detection of disease is often critical to how successful treatment can be. Therefore, the development of new methods of diagnosis is a hot research field, where every small step is of great importance. In an article in the latest issue of Molecular & Cellular Proteomics, Uppsala University...

Study shows hope for early diagnosis of Alzheimer's

Research by faculty and staff at Rowan University, Glassboro, N.J.; the University of Pennsylvania School of Medicine; and Drexel University may lead to better diagnosis of early-stage Alzheimer’s disease. In a $1.1-million National Institutes of Health’s National Institute on Aging study that te...

Key to early diagnosis of autism may be in the placenta

Researchers at Yale School of Medicine have discovered in the placenta what may be the earliest marker for autism, possibly helping physicians diagnose the condition at birth, rather than the standard age of two or older. The findings are reported in the June 26 online issue of Biological Psychi...

Advanced genomics and proteomics improve the diagnosis and treatment of a deadly lung disease

A team of Howard Hughes Medical Institute (HHMI) scientists has peeled back some of the mystery of how cells are able to turn off genes selectively to control critical events of development. The new insights arise from the first clear molecular images of the structure of Dicer, an enzyme that enabl...

New mitochondrial DNA gene chip may be early cancer diagnosis tool

A pilot study at the National Institute of Standards and Technology (NIST), in support of the National Cancer Institute's Early Detection Research Network (EDRN), has validated the measurement accuracy of new techniques that use mitochondrial DNA as an early indicator for certain types of cancer. A...

Owl genomics presents a HEPATOCHIP for diagnosis of non-alcoholic steatohepatitis

OWL Genomics, biotechnological company, has presented at the CIC bioGUNE hold at the Bizkaia Technological Park (Derio), the first DNA chip concerning diagnosis and prognosis of non-alcoholic steatohepatitis (NASH), allowing the discrimination between normal, steatosis and NASH predisposed subjects...

Stem cell 'daughters' lead to breast cancer

...n the long-term, breast biopsies might be able to reveal misbehaving luminal progenitor cells. What's more, certain 'markers' might one day help guide diagnosis and treatment. "For example, c-KIT is a key marker of the luminal progenitor cell and I expect we will see an increase in pathologists routinely using...

A crystal ball for brain cancer?

...ain scans show no trace of his cancer at all. The former marathon runner, ordained minister and father of two says he hasn't felt this good since his diagnosis last winter. In welcome news for patients like McNabb, the U.S. Food and Drug Administration approved the use of Avastin last month for the treatme...

Study shows cancer vaccines led to long-term survival for patients with metastatic melanoma

...dation. "There is continued interest in developing new therapies for melanoma patients with recurrent or distant metastatic disease at the time of diagnosis because there are no systemic therapies that can be relied upon to cure them," said Robert O. Dillman, M.D., F.A.C.P., executive medical and scientifi...

Researchers develop 'brain-reading' methods

...ing a means for identifying higher-level mental functions, such as 'lying' or abstract reasoning. They potentially also could pave the way for earlier diagnosis and better treatment of mental disorders, such as autism and schizophrenia, by offering a means for identifying very subtle abnormalities in brain act...

DOE-funded research projects win 46 R&D 100 Awards for 2009

...t Gamma Camera This high-resolution nuclear medical probe can pinpoint the locale of cancer tissue in the prostate gland in detail at an early stage. diagnosis is easier using the gamma camera, rather than conventional ultrasound imaging, because the camera can more easily detect the small cancerous tissues a...

C. difficile spores spread superbug

...nvironment and open the door for the development of treatments and improved diagnosis of C. difficile . At present, healthcare professionals manage the threa...e determining the host factors important in disease and will lead to better diagnosis and treatment strategies to reduce the burden of C. difficile -associated ...

Results from trials of DHA in Alzheimer's disease and age-related cognitive decline

... Thies, PhD, Chief Medical & Scientific Officer at the Alzheimer's Association. "For that to happen, we need to get much better at early detection and diagnosis of Alzheimer's, in order to test therapies at earlier stages of the disease and enable earlier intervention." Other research studies from ICAD 2009...

AACR applauds nomination of Francis S. Collins, M.D., Ph.D., to be the new NIH director

...insight will be invaluable," said Jacks. The AACR looks forward to working with Dr. Collins as new scientific discoveries transform the prevention, diagnosis and treatment of cancer. The AACR urges the Senate to confirm him with haste. ...

2 reproductive factors are important predictors of death from ovarian cancer

...e of these factors on a patient's survival after a diagnosis of ovarian cancer. Cheryl L. Robbins, Ph.D., a...oductive factors that may influence survival after diagnosis with this serious disease." Robbins and colleag...st age at menarche also had poorer survival. After diagnosis of ovarian cancer, participants whose menarche beg...

Chromosomal problems affect nearly all human embryos

...an 35 years old), fertile couples who had asked for preimplantation genetic diagnosis (PGD). PGD is carried out where one or both parents have a known genetic ab...crucial breakthrough that will change the way we do preimplantation genetic diagnosis and PGS and help to advance our ability to improve human fertility," said M...

Women with endometriosis need special care during pregnancy to avoid risk of premature birth

...ion today*. The researchers investigated the association between adverse pregnancy outcome, assisted reproduction technology (ART), and a previous diagnosis of endometriosis in 1 442 675 single births to Swedish women. They found 13 090 births among 8922 women diagnosed with endometriosis. Compared with wo...

University of Leicester researchers discover new fluorescent silicon nanoparticles

...ssor Chris Binns and Dr Glenn Burleigh, also incorporates this new method of synthesis. They are aiming to link nanoparticles to drugs involved in the diagnosis and treatment of cancer. Professor of Nanoscience in the Department of Physics and Astonomy, Chris Binns said: "Nanotechnology, that is, the use of...

New test can detect both genetic and chromosomal abnormalities in embryos

...an work in cells taken from embryos that have already been diagnosed with the cystic fibrosis gene mutation using conventional preimplantation genetic diagnosis (PGD). Gary Harton, PGD scientific director of the Genetics & IVF Institute in Fairfax, Virginia (USA) told a news briefing: "Karyomapping is a uni...

Single thawed embryo transfer after PGD does not affect pregnancy rates

... Amsterdam, The Netherlands: Transferring just one embryo at a time to a woman's womb after embryos have undergone preimplantation genetic diagnosis (PGD) and freezing at the blastocyst stage has become a real option after researchers achieved pregnancy rates that were as good as those for blastocy...

Gene expression findings a step toward better classification and treatment of juvenile arthritis

... JIA is an inflammatory and sometimes disabling joint disease that affects an estimated 294,000 children in the United States. At present, making a diagnosis of JIA is imprecise and based largely on the presence of joint inflammation persisting for at least six weeks, for which no other cause can be determi...
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