Triggering muscle development -- a therapeutic cure for muscle wastage?
Scientists in the UK and Denmark have shown that if elderly men were given growth hormone and exercised their legs showed an appreciable muscle mass increase. Dr. Geoff Goldspink (Royal Free and University College Medical School, UK) says: "This raises the question: Can age-related loss of muscle ...Trio of signals converge to induce liver and pancreas cell development in the embryo
PHILADELPHIA - Understanding the molecular signals that guide early cells in the embryo to develop into different organs provides insight into ways that tissues regenerate and how stem cells can be used for new therapies. With regenerated cells, researchers hope to one day fill the acute shortage ...Pushmi-pullyu of B-cell development discovered
Although every cell in the body carries the genes necessary to function as an antibody-producing B cell, only a small proportion of stem cells mature into those important immune-system cells. James Hagman, PhD, Professor of Immunology at National Jewish Health and his colleagues have identified tw...Amarna Therapeutics B.V. and TNO announce SVac research and development partnership
Leiden, The Netherlands, June 09, 2009 / b3c newswire / - Dutch biotechnology company Amarna Therapeutics B.V. and the Netherlands Organisation for Applied Scientific Research TNO today announced that they have entered into a collaboration agreement to further develop Amarna’s viral gene...Investigating the development of mechanosensitivity
Researchers of the Max Delbrck Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have gained crucial insight into how mechanosensitivity arises. By measuring electrical impulses in the sensory neurons of mice, the neurobiologists and pain researchers Dr. Stefan G. Lechner and Professor Gar...Strong immune response to new siRNA drugs in development may cause toxic side effects
New Rochelle, NY, May 20, 2009Small synthetic fragments of genetic material called small interfering RNA (siRNA) can block production of abnormal proteins; however, these exciting new drug candidates can also induce a strong immune response, causing toxic side effects. Understanding how siRNA stim...'Beating' heart machine expedites research and development of new surgical tools, techniques
A new machine developed at North Carolina State University makes an animal heart pump much like a live heart after it has been removed from the animal's body, allowing researchers to expedite the development of new tools and techniques for heart surgery. The machine saves researchers time and mone...$1.6 million grant to lead development of resistance-detecting field kit
Liverpool School of Tropical Medicine (LSTM) has been awarded a 1.1m grant by the US National Institutes of Health to lead a five year project to develop a Field Applicable Screening Tool (FAST) kit to detect resistance to public health insecticides in mosquitoes. The two principal methods for ...NIH grants $122 million in Institutional Development Awards
The National Center for Research Resources (NCRR), part of the National Institutes of Health, announced today it will provide up to an estimated $122 million over the next five years to fund Institutional Development Award (IDeA) Networks of Biomedical Research Excellence (INBRE) in seven IDeA-eli...Researchers discover that gene switches on during development of epilepsy
WINSTON-SALEM, N.C. A discovery made by researchers at Wake Forest University School of Medicine while studying mice may help explain how some people without a genetic predisposition to epilepsy can develop the disorder. In a study published this month in the Journal of Neuroscience , senior ...NIH funds development of resistance-breaking insecticides to reduce malaria transmission
Blacksburg, Va. Researchers from Virginia Tech and Molsoft LLC have received a five-year, $3.557 million grant from the National Institute of Allergy and Infectious Diseases (NIAID) to continue their promising work on a new class of resistance-breaking insecticides to reduce malaria transmission....Changes in gene may stunt lung development in children
PITTSBURGH, March 26 Mutations in a gene may cause poor lung development in children, making them more vulnerable to diseases such as chronic obstructive pulmonary disease (COPD) later in life, say researchers at the University of Pittsburgh Graduate School of Public Health and the German Researc...Smithsonian scientist warns that palm oil development may threaten Amazon
Oil palm cultivation is a significant driver of tropical forest destruction across Southeast Asia. It could easily become a threat to the Amazon rainforest because of a proposed change in Brazil's legislation, new infrastructure and the influence of foreign agro-industrial firms in the region, acc...Fighting global warming offers growth and development opportunities
Combating climate change may not be a question of who will carry the burden but could instead be a rush for the benefits, according to new economic modeling presented today at "Climate Change: Global Risks, Challenges & Decisions" hosted by the University of Copenhagen. Contrary to current cos...VUANCE Announces Crime Scene Security and Evidentiary Tracking Development Project
FRANKLIN, Wis., Dec. 9 /PRNewswire-FirstCall/ -- VUANCE, Ltd. (Nasdaq: VUNC ), a leading provider of innovative Radio Frequency Verification Solutions, including active RFID, electronic access control, credentialing, accountability and incident response management, today announced that it has be...New dummy design and development wins US Department of Defense award
Blacksburg, Va. -- The Virginia Tech Wake Forest University's School of Biomedical Engineering and Science's Center for Injury Biomechanics has received the Army Modeling and Simulation Award for 2008. The Office of the Deputy Chief of Staff of the Army and Director of the Army presented the ...Female embryonic sexual development driven by universal factor
A gene essential to the growth and development of most organ systems in the body also is vital to female but not male embryonic sexual development, scientists report this month. The study, from researchers at the University of Illinois and the University of Texas, appears in Human Molecular ...Research pushes back history of crop development 10,000 years
Researchers led by Dr Robin Allaby of the University of Warwick's plant research arm Warwick HRI have found evidence that genetics supports the idea that the emergence of agriculture in prehistory took much longer than originally thought. Until recently researchers say the story of the origin o...Height linked to risk of prostate cancer development and progression
PHILADELPHIA A man's height is a modest marker for risk of prostate cancer development, but is more strongly linked to progression of the cancer, say British researchers who conducted their own study on the connection and also reviewed 58 published studies. In the September issue of Cancer Ep...AACR hosts Molecular Diagnostics in Cancer Therapeutic Development Meeting
What: The AACR Molecular Diagnostics in Cancer Therapeutics Development Meeting features the latest findings in laboratory, translational and clinical cancer research. This year's meeting focuses on new biologic markers and imaging methods. To help you take advantage of the meeting's scienti...Johns Hopkins scientists discover what drives the development of a fatal form of malaria
Platelets those tiny, unassuming cells that cause blood to clot and scabs to form when you cut yourself play an important early role in promoting cerebral malaria, an often lethal complication that occurs mostly in children. Affecting as many as half a billion people in tropical and subtropical ...NJIT biomedical engineer receives NSF Career Development Award
Bryan J. Pfister, PhD, a specialist in neural tissue engineering, has been awarded a prestigious Faculty Early Career Development Award by the National Science Foundation (NSF). Pfister, who is an assistant professor of biomedical engineering at NJIT's Newark College of Engineering, received the...Carnegie Mellon researchers urge development of low carbon electricity
PITTSBURGHCarnegie Mellon Universitys Constantine Samaras and Kyle Meisterling report that plug-in hybrid electric vehicles could help reduce greenhouse gas emissions that fuel global warming, but the benefits are highly dependent on how the electricity system changes in the coming decades. ...National Lung Cancer Partnership announces winner of 2007 Career Development Award
MADISON, Wis. National Lung Cancer Partnership is pleased to announce that Adam Marcus, Ph.D., of the Winship Cancer Institute at Emory University is the winner of the organizations 2007 Career Development Award. The Career Development Award, in the amount of $80,000, provides two years of ...Trainor Lab characterizes gene essential for prenatal development of nervous system
The Stowers Institutes Trainor Lab has demonstrated the role of a gene important to the embryonic development of the nervous system, a process that requires coordination of differentiation of immature neural cells with the cycle of cell division that increases their numbers. Until now, the mechani...Study of successful drug targets could hasten development of new medications
Guidance from an innovative computational approach could speed up the process and cut down the cost of new drug development, researchers from the University of Chicago Medical Center and Columbia University suggest in a study to be published in the February 2008 issue of Genome Research, available...Search for the 'on' switches may reveal genetic role in development and disease
DURHAM, N.C. -- A new resource that identifies regions of the human genome that regulate gene expression may help scientists learn about and develop treatments for a number of human diseases, according to researchers at Dukes Institute for Genome Sciences & Policy (IGSP). The majority of DNA in...Gene Networks in Animal Development and Evolution Feb. 15 and 16
The National Academy of Sciences' Sackler Colloquium series will hold a meeting on gene regulatory networks. These networks represent the genomic program for the development of animal embryos, body parts, and cell types. The meeting will focus on four areas -- gene regulatory networks that contr...New studies suggest brain overgrowth in 1-year-olds linked to development of autism
Boca Raton, FL, December 8, 2007 Brain overgrowth in the latter part of an infants first year may contribute to the onset of autistic characteristics, according to research presented today at the American College of Neuropsychopharmacology (ACNP) annual meeting. These findings support concurrent ...DNA methylation shown to promote development of colon tumors
CAMBRIDGE, Mass. (December 1, 2007) Damaged or defective genes have long been known to be the cause of some cancers. Over the past decade, however, scientists have discovered that even healthy genes can be switched on or off and can cause cancer without any changes in the underlying DNA sequencea...Further development of Water Framework Directive necessary
Leipzig. Experts from 20 countries have called for the guidance documents for the implementation of the European Water Framework Directive (WFD) to be updated. The consensus among the scientists and stakeholders who discussed risks for European rivers at the Helmholtz Centre for Environmental Rese...Team of scientists develops non-invasive method to track nerve-cell development in live human brain
A team of scientists including researchers at Cold Spring Harbor Laboratory (CSHL) have identified and validated the first biomarker that permits neural stem and progenitor cells (NPCs) to be tracked, non-invasively, in the brains of living human subjects. This important advance could lead to sign...Odd protein interaction guides development of olfactory system
Scientists have discovered a strange mechanism for the development of the fruit fly antennal lobe, an intricate structure that converts the chaotic stew of odors in the environment into discrete signals in the brain. The fruit fly antennal lobe is analogous to the olfactory bulb in humans. R...NIH grants $33 M in institutional development awards to 3 states
The National Center for Research Resources (NCRR), a part of the National Institutes of Health (NIH), announced today it has provided nearly $33 million to fund three new Institutional Development Awards (IDeA). The awards support multidisciplinary centers each concentrating on one general area o...Study shows housing development on the rise near national forests
PORTLAND, Ore. October 25, 2007. Americas national forests and grasslands provide the largest single source of freshwater in the United States, habitat for a third of all federally listed threatened or endangered species, and recreation opportunities for people (about 205 million visits are made a...Researchers find signal that switches on eye development -- could lead to 'eye in a dish'
Researchers at the University of Warwick, funded by Wellcome Trust, have uncovered a crucial signal that switches on eye development. This discovery will greatly assist researchers looking at stem cells connected to eye development and opens up an avenue of research that could eventually lead to a...