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Researchers describe 'implausible' chemistry that produces herbicidal compound

CHAMPAIGN, Ill. A soil microbe that uses chemical warfare to fight off competitors employs an unusual chemical pathway in the manufacture of its arsenal, researchers report, making use of an enzyme that can do what no other enzyme is known to do: break a non-activated carbon-carbon bond in a sing...

Notre Dame researchers describe new tool for evaluating 'managed relocations'

Three University of Notre Dame researchers are among the authors of a new paper that describes a ground-breaking tool designed to help policy makers determine when and how to use an environmental strategy known as "managed relocation." Jessica Hellmann and Jason McLachlan, assistant professors...

Pitt researchers describe molecular '2-step' leading to protein clumps of Huntington's disease

PITTSBURGH, March 8 In a paper published in the early online version of Nature Structural and Molecular Biology , researchers at the University of Pittsburgh School of Medicine deconstruct the first steps in an intricate molecular dance that might lead to the formation of pathogenic protein clum...

Researchers describe protease inhibitor that may aid in diabetic retinopathy treatment

NEW YORK, Jan. 21, 2009 Researchers from Joslin Diabetes Center, Boston, and ActiveSite Pharmaceuticals, Inc., San Francisco, announced today that they have demonstrated that a specific inhibitor of the protease plasma kallikrein, ASP-440, developed by ActiveSite Pharmaceuticals, may provide a ne...

Wisconsin researchers describe how digits grow

MADISON - Researchers at the University of Wisconsin School of Medicine and Public Health (SMPH) are wagging a finger at currently held notions about the way digits are formed. Studying the embryonic chick foot, the developmental biologists have come up with a model that explains how digits gro...

MGH researchers describe new way to identify, evolve novel enzymes

The intricate interplay of proteins and other chemicals that underlies most biological activities requires the participation of enzymes, specialized molecules that accelerate chemical reactions between molecules. The creation of totally new enzymes can help improve the synthesis of chemicals and p...

Scientists describe new African monkey genus ?first in 83 years

For the first time in 83 years, scientists have identified a new genus of a living primate from Africa, according to research to be published by Science May 11 in the online Science Express. "This is exciting news because it shows that the 'age of discovery' is by no means over," says William S...

FSU biologists describe key role of signal-transcribing gene during cell cycle

Study in Oct. 1 'Development' shows when, where Alzheimer's, some cancers and genetic ills beginT. Biologists at Florida State University have uncovered the pivotal role of a gene called "Cut" that acts as a sort of middleman in cell-to-cell communication. A DNA-binding protein, Cut interprets an...

MUHC scientists describe genetic resistance to rampant virus

MUHC researchers have defined genetic resistance to the widespread virus, cytomegalovirus (CMV)--a member of the viral group that causes some of the world's most prevalent diseases, such as herpes, chicken pox and mononucleosis. The groundbreaking research published in Nature Genetics last week, pr...

New DNA and RNA aptamers offer unique therapeutic advantages

...peutic strategies that have the highest likelihood of success. In the article entitled "Therapeutic Applications of DNA and RNA Aptamers," the authors describe the methods used to identify aptamers that specifically bind protein drug targets of interest, the types of modifications that have been made to aptam...

Pinhead-size worms + robot = new antibiotics

...eening of potential new antibiotics in living animals infected with bacteria to see the effects on the entire body of the animal. The scientists describe successful use of such a whole-animal high throughput screening test automated with a robot to test the effects of 37,000 potential drugs on C. ele...

August 2009 Geology and GSA Today media highlights

...d Industrial Research Organisation (CSIRO), Exploration and Mining, 26 Dick Perry Avenue, Perth, WA 6151, Australia. Pages 707-710. Deditius et al. describe alternating zones of copper- and arsenic-rich pyrite from gold-deposits at Pueblo Viejo (Dominican Republic) and Yanacocha (Peru). Arsenic-rich zones ...

Carnegie Mellon team makes sequestration recommendations

...ions in future CO2 emissions that Congress and the Obama administration are now proposing. The policy briefs, available from http://www.CCSReg.org, describe changes to federal law and agency rules needed to overcome regulatory and legal barriers to large-scale deployment of carbon sequestration. The CCS...

Biodiesel on the wing: A 'green' process for biodiesel from feather meal

...rcent fat content, feather meal has potential as an alternative, nonfood feedstock for the production of biofuel, the report says. The researchers describe a new process for extracting fat from chicken feather meal using boiling water and processing it into biodiesel. Given the amount of feather meal gene...

Chasing tiny vehicles

...and quickly transports them towards the cell nucleus the ultimate target for the gene. The research team is now in a position to characterize and describe in great detail the individual steps along this path. "Our new approach has also revealed bottlenecks in nanoferry transport," Bruchle reports. "We sa...

Reviews of microbial gene language published in special issue of Trends in Microbiology

...en articles describing how a universal language to describe genes is bringing benefits to the study of the mic...uage that gives researchers a shared vocabulary to describe disease-related and beneficial interactions betwee...he Gene Ontology was the development of terms that describe the functions of gene products that are made by on...

Toxin detection as close as an inkjet printer

...he July issue of Analytical Chemistry , John Brennan and his research team at McMaster University, working with the Sentinel Bioactive Paper Network, describe a method for printing a toxin-detecting biosensor on paper using a FujiFilm Dimatix Materials Printer. The researchers demonstrated the concept on ...

Faster, more cost-effective DNA test for crime scenes, disease diagnosis

...obes in a patient's blood to diagnose an infection. Current PCR methods, however, are too expensive and cumbersome for wide use. The scientists describe development and testing of a new PCR method, called the universal QProbe system, that overcomes these problems. Existing PCR processes require several...

Plastics chemical retards growth, function of adult reproductive cells

...dy is the first to show that chronic exposure to low doses of BPA can impair the growth and function of adult reproductive cells. The researchers will describe their findings this month at the annual meeting of the Society for the Study of Reproduction. A healthy, mature follicle, called an antral follicle...

Harvard scientists solve mystery about why HIV patients are more susceptible to TB infection

...ulosis (TB) infection. In their report, appearing in the July 2009 print issue of the Journal of Leukocyte Biology ( http://www.jleukbio.org ) they describe how HIV interferes with the cellular and molecular mechanisms used by the lungs to fight TB infection. This information is crucial for researchers dev...

The sound of light: Innovative technology shatters the barriers of modern light microscopy

...gh-resolution fluorescence images from this depth because of the strong scattering of light. In the Nature Photonics journal, the Munich researchers describe how they can reveal genetic expression within live fly larvae and fish by "listening to light". In the future this technology may facilitate the exami...

Neural stem cell differentiation factor discovered

...his process. So far, only stimulating extracellular ligands of Notch receptors had been described. Biochemists of Goethe University Medical School now describe a long time assumed but not yet identified soluble Notch inhibitor. Franfurt scientists led by Mirko Schmidt and Ivan Dikic reported in the renown...

Study on keeping nuclear bombs from US ports shows misplaced fear over cargo scanning cost

...ve (SFI), could be adapted to successfully manage the large volume of inspections at ports around the world. Under a variant of SFI that the authors describe as an industry-centric model, a larger number of containers virtually all those originating outside the U.S. would receive a rapid screening via low...

DNA template could explain evolutionary shifts

...her similar but significantly different stretch of DNA before it switches back to the appropriate area. In this newer report, Lupski and colleagues describe how this process called fork stalling and template switching (FoSTeS) in humans or microhomology-mediated break-induced replication (MMBIR) in simple...

The SIB recognizes the next generation of bioinformaticians

... progressively weaker towards late development, in early development on the genome", which contradicts the "hourglass" model that is generally used to describe vertebrate developmental constraint. Once published, this paper was immediately recognised as an important contribution to the general understandi...

7th annual [BC]2 Basel Computational Biology Conference 'Molecular Evolution' June 18-19, 2009

...antigenic evolution of influenza viruses". He will describe the study of influenza virus evolution, required f... on E. coli. In his address, Professor Lenski will describe in more detail recent findings in this project pro...imple, general models of evolutionary processes to describe genomic and phenomic evolution. Dr. Koonin is a Se...

American Chemical Society weekly presspac -- June 10, 2009

...ldehyde with conventional tests. The scientists describe development and use of a modified mass spectrometr...y detection of kidney disease. The scientists describe tests of an experimental "electronic nose" on exha...ight. The new approach yielded what the scientists describe as the most efficient and stable source of pure wh...

Newly discovered snow roots are 'evolutionary phenomenon'

... a previously unknown and entirely unique form of plant root has been discovered. Lead Scientist Professor Hans Cornelissen and his Russian-Dutch team describe this finding today in Ecology Letters . The root belongs to the small alpine plant Corydalis conorhiza and unlike normal roots, which grow into so...

'Honey bee health' of concern at Western Apicultural Society conference

...e University, Pullman, will cover ""Washington State Honey Bee Health Program: Breeding, Diagnostics and Insecticide Tolerance." "Jerry's likely to describe and display his hand-held, acoustic monitoring device that 'listens' to the health of a honey bee colony," Mussen said On Wednesday morning, Aug. 1...

Bullies have harassed 14 percent of workers over past 6 months

...to negative consequences in workers, their social and family environment, and can impacts on their job performance". Gonzlez and Graa were able to describe the characteristics of mobbing within the working population in Spain by using information from the nearly 3,000 valid responses received from the Neg...

Aluminum-oxide nanopore beats other materials for DNA analysis

...echanical properties, enhanced noise performance and increased lifetime over their silicon-oxide and silicon-nitride counterparts." The researchers describe the fabrication and operation of the aluminum-oxide nanopore sensor in a paper accepted for publication in Advanced Materials , and posted on the jou...

New device detects heart disease using less than one drop of blood

...ers from Harvard and Northeastern universities in Boston. In a research report published online in The FASEB Journal ( http://www.fasebj.org ), they describe how this device can measure and collect a type of cells needed to build vascular tissue, called endothelial progenitor cells, using only 200 microlite...

American Chemical Society's weekly PressPac -- May 27, 2009

...ets, disk-shaped particles in the blood that form clots. The scientists describe development and lab testing of silver nanoparticles that seem to keep plate...suitable for drugs that must be taken month after month. The scientists describe development of a first-of-its-kind microcapsule made from lipid oils and na...

Scientists develop a new HIV microbicide -- and a way to mass produce it in plants

...ome major hurdles of high efficacy, low cost, and wide availabilityall of which we address in this study." In the research paper, Ma and colleagues describe how they combined two protein microbicides (b12 monoclonal antibody and cyanovirin-N) into a single "fusion" molecule and showed that this molecule is...

Scientists announce top 10 new species, issue SOS

...lanet." According to Wheeler, a new generation of tools are coming online that will vastly accelerate the rate at which we are able to discover and describe species. "Most people do not realize just how incomplete our knowledge of Earth's species is or the steady rate at which taxonomists are exploring ...

Healing wounds with lasers, vehicles that drive themselves, other cutting-edge optics

...week's CLEO/IQEC, GeoEye's Systems Engineering Director Michael Madden will describe some of the satellite's key features, such as the fact that it's the first ...tion") brought about by thermal energy. H. Jeff Kimble of Caltech will describe a new effort to counteract thermal noise and improve the sensitivity of int...

American Chemical Society's Weekly PressPac -- May 20, 2009

... shortness of breath and chills. The scientists describe their first-of-its kind identification of 33 prote...ble way to make these particles. The scientists describe an efficient one-step method for making nano-raspb...1986, failed within 20 years. The researchers describe development of an experimental memory device consi...

Scientists announce top 10 new species; issue SOS

...lanet." According to Wheeler, a new generation of tools are coming online that will vastly accelerate the rate at which we are able to discover and describe species. "Most people do not realize just how incomplete our knowledge of Earth's species is or the steady rate at which taxonomists are exploring ...

P[acman]-generated fruit fly gene 'library': A new research tool

...sh.imgen.bcm.tmc.edu/lab/ ), a professor of molecular and human genetics at BCM and a Howard Hughes Medical Institute investigator, and his colleagues describe the new libraries. P[acman] developed by Dr. Koen Venken ( http://flypush.imgen.bcm.tmc.edu/lab/koenv/index.html ) in Bellen's laboratory allows sc...

Jungle yeast

...he Amazon jungle. In a paper published on-line in FEMS Yeast Research , IFR scientists and colleagues from Pontificia Universidad Catlica del Ecuador describe the novel characteristics of Candida carvajalis sp. nov . Yeasts have long been the powerhouses of our food and fermentation industries. Each new s...
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