Delivery in Biological News

New cancer drug delivery system is effective and reversible

CHAMPAIGN, Ill. For cancer drug developers, finding an agent that kills tumor cells is only part of the equation. The drug must also spare healthy cells, and ideally its effects will be reversible, to cut short any potentially dangerous side effects. University of Illinois researchers report...

RNA molecules, delivery system improve vaccine responses, effectiveness

AUSTIN, Texas A novel delivery system that could lead to more efficient and more disease-specific vaccines against infectious diseases has been developed by biomedical engineers at The University of Texas at Austin. The findings use specific ribonucleic acid (RNA) molecules to significantly bo...

ID Solutions Achieves Full-Production Delivery and Payment for Fingerprint Processing Software for TWIC

TSA's Transportation Worker Identification Credential (TWIC) Program Ensures No Fraudulent Duplicate Enrollments Using ID Solutions Technology MIAMI BEACH, Fla., Sept. 22 /PRNewswire/ -- ID Solutions, Inc., the world's leader in low-cost, high-performance solutions for trusted credential as...

Cancer drug delivery research at Case Western Reserve University cuts time from days to hours

CLEVELAND Researchers at Case Western Reserve University have developed a technique that has the potential to deliver cancer-fighting drugs to diseased areas within hours, as opposed to the two days it currently takes for existing delivery systems. Using laboratory mice, drug delivery time from...

Test of bacteria toxin delivery system could pave way for new antibiotic drugs

Jerusalem, June 16, 2008 Researchers at the Hebrew University of Jerusalem have achieved a breakthrough in monitoring the toxin-delivery system of highly pathogenic bacteria an accomplishment that could help pave the way for new drugs that will be capable of neutralizing those germs. Most b...

Remarks Prepared for Delivery By Attorney General Michael B. Mukasey At the Ministerial Press Conference

BERLIN, March 11 /PRNewswire-USNewswire/ -- The following statement was issued today by the U.S. Department of Justice Office of Public Affairs: Good afternoon. I want to thank Interior Minister Schauble and Justice Minister Zypries for their hospitality during our visit and for their dedi...

e-SMART Technologies Continues Delivery of Its New Super SMART Card in South Korea

NEW YORK and SEOUL, South Korea, Feb. 28 /PRNewswire-FirstCall/ -- e-SMART(R) Technologies, Inc., (Pink Sheets: ESMT); with its parent company IVI Smart Technologies, Inc., ("e-SMART"(R) or the "Company") is pleased to announce that it has signed a contract to deliver its newest Super SMART Ca...

Carnegie Mellon researchers to develop new drug delivery system

PITTSBURGH Carnegie Mellon Universitys Stefan F. Zappe is using adult neural stem cells to develop a new stem cell-based drug delivery therapy that may ultimately help treat a variety of inherited genetic disorders like Hunter syndrome. Zappe, an assistant professor of biom...

Computer solution to delivery problem

With the gift-giving season almost upon us and increasing concerns about the environmental effects of all those deliveries and pickups, it is timely that researchers should turn their attention to the so-called Traveling Salesman Problem. Writing in a forthcoming issue of the Inderscience publicat...

'Jumping genes' could make for safer gene delivery system

MADISON - To move a gene from point A to point B, scientists and gene therapists have two proven options: a virus, which can effectively ferry genes of interest into cells, and a plasmid, an engineered loop of DNA that can do the same thing, albeit usually only on a short-term basis. The catch ...

Carnegie Mellon scientists develop nanogels that enable controlled delivery of carbohydrate drugs

PITTSBURGHCarnegie Mellon University scientists have developed tiny, spherical nanogels that uniformly release encapsulated carbohydrate-based drugs. The scientists created the nanogels using atom transfer radical polymerization (ATRP), which will ultimately enable the nanogels to deliver more dru...

Nanotechnology holds promise for STD drug delivery

New Haven, Conn. Yale researchers describe a breakthrough in safe and effective administration of potential antiviral drugs small interfering RNA (siRNA) molecules that silence genes the first step in development of a new kind of treatment for sexually transmitted diseases (STDs). The work is r...

Depression during pregnancy can double risk of preterm delivery

October 23, 2008 (Oakland, Calif.) - Depressed pregnant women have twice the risk of preterm delivery than pregnant women with no symptoms of depression, according to a new study by the Kaiser Permanente Division of Research. The study is published online in the Oxford University Press's journal ...

New paradigm for cell-specific gene delivery

Researchers from Northwestern University and Texas A & M University have discovered a new way to limit gene transfer and expression to specific tissues in animals. In studies to determine how plasmids enter the nuclei of non-dividing cells, the group previously identified a region of a smooth mus...

MIT: Stripes key to nanoparticle drug delivery

CAMBRIDGE, Mass.--In work that could at the same time impact the delivery of drugs and explain a biological mystery, MIT engineers have created the first synthetic nanoparticles that can penetrate a cell without poking a hole in its protective membrane and killing it. The key to their approach?...

Micro-origami: USC folds up micrometer-scale 'voxels' for drug delivery

Researchers at the USC Information Sciences Institute have demonstrated a way to manufacture miniscule closed containers that might be used to deliver precise micro- or even nano-quantities of drugs. According to ISI project leader Peter Will, who is also a research professor in the Viterbi Sch...

Fewer babies born after Caesarean delivery

Women who have a Caesarean delivery for their first child go on to have fewer children than women who give birth in the traditional way. This is shown in a study from the Norwegian Institute of Public Health (NIPH) and University of Bergen. Researchers at the NIPHs Medical Birth Registry and th...

Researchers develop better membranes for water treatment, drug delivery

CHAMPAIGN, Ill. Researchers at the University of Illinois have developed a new generation of biomimetic membranes for water treatment and drug delivery. The highly permeable and selective membranes are based on the incorporation of the functional water channel protein Aquaporin Z into a novel A-B...

Nanoengineers mine tiny diamonds for drug delivery

EVANSTON, Ill. --- Northwestern University researchers have shown that nanodiamonds -- much like the carbon structure as that of a sparkling 14 karat diamond but on a much smaller scale -- are very effective at delivering chemotherapy drugs to cells without the negative effects associated with cur...

Gene therapy delivery of nerve growth factors reverses erectile dysfunction in animal model

Rats with erectile dysfunction, or ED, that were injected with a gene therapy vector containing either of two nerve growth factors were able to regain normal function after four weeks, according to a study conducted by University of Pittsburgh School of Medicine researchers. These findings are bei...

New designer lipid-like peptide with lipid nanostructures for drug delivery systems

Scientists from Institute of Biophysics and Nanosystems Research (IBN), Austrian Academy of Sciences and of Centre for Biomedical Engineering, Massachusetts Institute of Technology, Cambridge, USA report the study of “Tuning Curvature and Stability of Monoolein Bilayers by Designer Lipid-Like Pept...

Nanoparticles for delivery of prostate cancer treatment

Alan Garen , professor of molecular biophysics and biochemistry at Yale has received a $100,000 award from the Prostate Cancer Foundation to expand research on the delivery of a targeted therapy for prostate cancer using nanoparticles. Garen and his collaborator Zhiwei Hu have developed a w...

Scientists force viruses to evolve as better delivery vehicles for gene therapy

Viruses and humans have evolved together over millions of years in a game of one-upmanship that, often as not, left humans sick or worse. Now, a University of California, Berkeley, researcher has shown that viruses - in this case, a benign one - can be forced to evolve in ways to benefit humans. ...

Cellular scale drug delivery from the inside out

Delivering a dose of chemotherapy drugs to specific cancer cells without the risk of side affects to healthy cells may one day be possible thanks to a nanoscale drug delivery system being explored by researchers at the U.S. Department of Energy's Ames Laboratory. Using tiny silica particles call ...

Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates

Ground-breaking results from researchers at Harvard Medical School and Massachusetts Institute of Technology (MIT), USA, disclosed at the 13th European Cancer Conference (ECCO) have shown for the first time that targeted drug delivery is possible using nanoparticle-apatamer conjugates. Nucleic a...

'Cookbook recipes' would cure disease with nontoxic DNA delivery systems

Scientists studying the structure and interaction of negatively charged lipids and DNA molecules have created a "cookbook" for a class of nontoxic DNA delivery systems that will assist doctors and clinicians in the safe and effective delivery of genetic medicine. As reported in the Aug. 9 issue o...

“Hitchhiking?Viruses as Cancer Drug Delivery System

About five to seven million years ago, when the lineage of humans and chimpanzees split, edible root plants similar to rutabagas and turnips may have been one of the reasons. According to research by anthropologists Greg Laden of the University of Minnesota and Richard Wrangham of Harvard Universit...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

Transferrin, a plasma protein found in blood, can be fused with large, protein-based drugs such as granulocyte colony-stimulating factor (G-CSF) to create a new oral compound that is capable of surviving the journey through the gastrointestinal (GI) tract and then able to cross over into the bloods...

New methods of gene delivery using lasers

Leading laser scientists at the University of St Andrews have developed a new method of delivering genes to cells using laser light. The new technique, which is cheap and powerful, could have important implications for future studies in biomedicine and healthcare. Optical technology has huge pot...

Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth

... PHILADELPHIA Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer ce...nic biodegradable beta-amino ester polymer as a vector for the nanoparticle delivery of a DNA encoding diphtheria toxin suicide gene. These nanoparticles were i...

Nanodiamonds deliver insulin for wound healing

...from the nanodiamond clusters and retained its function. Exploiting this pH-mediated release mechanism may provide unique advantages for enhanced drug delivery methods. The researchers also found the insulin slowly and consistently released from the nanodiamond clusters over a period of several days. In...

New supercomputer to reel in answers to some of Earth's problems

...sumer buying a PC, EMSL purchased a custom-made machine from HP specifically designed for the demands of computational chemistry. After the computer's delivery and set up (see Chinook being set up here ), EMSL asked its users to test the system during a period of time called acceptance testing. The man...

High-tech vehicle design boosts emergency rescue capacity

...clients and market trends. Its products include computer numerical control (CNC) manufactured superstructures for fire engines, mobile workshops, food delivery vehicles and military transport. It has a particular expertise in the adaptation of box bodies to Unimog off-road vehicle subframes. Different appr...

New drug may reduce heart attack damage

...g also reduces incidental cell and tissue death resulting from life-saving interventions such as balloon angioplasty and stent placements, or from the delivery of clot-busting drugs. Significantly, the heart's pumping action is protected by the drug, dramatically improving the patient's chances of a full ...

Ethiopian government celebrates rinderpest eradication

...partment of Public Health and Family Medicine at TUSM, repurposed a rinderpest vaccine that could be transported to rural areas without refrigeration. delivery of the previous vaccine was problematic due to heat sensitivity. FIC's Berhanu Admassu, DVM, MSc and Darlington Akabwai, DVM, assisted the Ethiopian g...

Reviews of microbial gene language published in special issue of Trends in Microbiology

...iptions of bacterial effector proteins, virulence factors, effector protein delivery systems, and infection by filamentous pathogens. Joo Setubal, Associate Pro...ich and diverse and Gene Ontology terms help to reveal common themes in the delivery of effector molecules by different microbes. Our understanding of the key s...

Parascript Signature Verification Technology Used by Moscow Law Firm to Detect Signature Fraud in $160,000 Debt Collection Case

...tain financial documents in a major debt collection case in Moscow, Russia leading to the recovery of $160,000 from fraudulent activity related to the delivery of saw-timber materials. Signature Xpert analyzed and verified suspect signatures against proven, valid signatures from job applications, labor ...

UK Identity and Passport Service and IBM Sign 7-year National Biometric Identity Service (NBIS) Contract

... contract will provide a secure database for storing facial and fingerprint images for the next generation of biometric passports and will support the delivery of the National Identity card." John Granger, General Manager, IBM Global Business Services, said: "At a time when the world is becoming increas...

New national genome center launched

...d is also committed to making cutting edge facilities available to UK industry. As part of the Norwich Research Park, TGAC will be a key player in the delivery of the Park's new vision which aims to create hundreds of new, high-value jobs. Dr Jane Rogers, Director of TGAC, said: "The Genome Analysis Cent...

Biological warfare in bacteria offers hope for new antibiotics

... biological warfare that takes place between competing bacteria. Understanding how this group of proteins work could help scientists develop new drug delivery methods to target the bacteria that cause diseases in people." "It's as though the colicins are carrying the equivalent of hand grenades which they...