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Death in Biological News

2 reproductive factors are important predictors of death from ovarian cancer

PHILADELPHIA Researchers from the Centers for Disease Control and Prevention (CDC) found that survival among women with ovarian cancer is influenced by age of menarche and total number of lifetime ovulatory cycles. This finding suggests that hormonal activity over the course of a woman's lifet...

Comprehensive cardiogenetic testing for families of sudden unexplained death victims can save lives

Vienna, Austria: Relatives of a young person who dies suddenly should always be referred for cardiological and genetic examination in order to identify if they too are at risk of sudden death, a scientist told the annual conference of the European Society of Human Genetics today (Tuesday 26 May)....

Alzheimer cell death in Zebrafish: Demise of neurons observed live for the first time

Extensive death of nerve cells leads to severe dementia in patients with Alzheimer's disease. Until now, it has only been possible to investigate the neuronal devastation in post mortem animal models, and by using complicated methods. Researchers at the German Center for Neurodegenerative Disease ...

Sudden cardiac death without recognizable cause

In about 10% of cases, sudden cardiac death (SCD) in young people is due to a cardiac gene defect. This was the conclusion drawn by Silke Kauferstein of the Department of Forensic Medicine of the Johann Wolfgang Goethe University, Frankfurt, and her coauthors in the current Deutsches rzteblatt In...

Burnham researchers discover 'on switch' for cell death signaling mechanism

LA JOLLA, Calif., January 5, 2009-- Scientists at Burnham Institute for Medical Research (Burnham) have determined the structure of the interactions between proteins that form the heart of the death inducing signaling complex (DISC), which is responsible for triggering apoptosis (programmed cell d...

Drops in blood oxygen levels may be key to sudden death in some epilepsy patients

(SACRAMENTO, Calif.) A new study by researchers at UC Davis Medical Center suggests that the sudden unexplained deaths of some epilepsy patients may be a result of their brains not telling their bodies to breathe during seizures. "Significant drops in blood oxygen levels are more common than w...

Caltech geobiologists discover unique 'magnetic death star' fossil

PASADENA, Calif.-- An international team of scientists has discovered microscopic, magnetic fossils resembling spears and spindles, unlike anything previously seen, among sediment layers deposited during an ancient global-warming event along the Atlantic coastal plain of the United States. The...

Genes that control cell death fingered in age-related hearing loss

Several genes that play a role in how our body's cells normally auto-destruct may play a role in age-related hearing loss, according to research published online in the journal Apoptosis a journal devoted to the topic of cell suicide, or programmed cell death. Doctors know that genetics play...

Breast cancer cells recycle to escape death by hormonal therapy

Many breast cancer cells facing potentially lethal antiestrogen therapy recycle to survive, researchers say. About 70 percent of breast cancer cells have receptors for the hormone estrogen, which acts as a nutrient and stimulates their growth. Patients typically get an antiestrogen such as tam...

Oxidative stress: Mechanism of cell death clarified

This press release is available in German . Life processes in cells require a reducing environment that needs to be sustained with the help of a large number of antioxidative enzymes. This may sound abstract and incomprehensible, but everyone knows the phenomenon that a piece of cut apple o...

New study casts further doubt on risk of death from higher salt intake

May 15, 2008 (BRONX, NY) Contrary to long-held assumptions, high-salt diets may not increase the risk of death, according to investigators from the Albert Einstein College of Medicine of Yeshiva University. They reached their conclusion after examining dietary intake among a nationally represent...

Researchers uncover mechanism of action of antibiotic able to reduce neuronal cell death in brain

Research Highlights: Mechanism of action of compound found to induce neurotransmitter activity in brain cells The findings may lead researchers to develop potential novel therapies to treat Alzheimer's disease, amyotrophic lateral sclerosis, Huntingtons disease, epilepsy, stroke/ischemia, d...

Programmed death boosts business

As credits crunch, recession bites, and business struggle to stay primed, researchers in Spain suggest that a more surgical approach to management and business practice is needed if a company is to survive. Writing in the International Journal of Management Practice from Inderscience Publishers, t...

MIT-led teams unravel heparin death mystery

CAMBRIDGE, Mass.--An international team of researchers led by MIT has explained how contaminated batches of the blood-thinner heparin were able to slip past traditional safety screens and kill dozens of patients recently in the United States and Germany. The team, led by Professor Ram Sasisekha...

Sudden Oak Death pathogen is evolving, says new study that reconstructs the epidemic

Berkeley - The pathogen responsible for Sudden Oak Death first got its grip in California's forests outside a nursery in Santa Cruz and at Mt. Tamalpais in Marin County before spreading out to eventually kill millions of oaks and tanoaks along the Pacific Coast, according to a new study led by res...

Vitamin D and calcium influence cell death in the colon, researchers find

Researchers at Emory University are learning how vitamins and minerals in the diet can stimulate or prevent the appearance of colon cancer. Emory investigators will present their findings on biological markers that could influence colon cancer risk in three abstracts at the American Association...

The birth and death of dopamine neurons: A new model for neurodegeneration

The gradual loss of dopamine neurons is a hallmark of many neurodegenerative diseases - Parkinsons Disease chief among them. Stem cell biology and regenerative medicine offer novel therapies for the restoration of dopamine neurons. This week in the online open-access journal PLoS Biology Dr. Raja...

Leading cause of death in 'preemies' might be controlled by resetting a molecular switch

Washington, D.C. -- Blocking signals from a key molecular receptor that normally switches on the intestines immune response but instead becomes too intense in the presence of stress and toxins may help reverse necrotizing enterocolitis (NEC), a leading cause of death in premature newborns, accor...

Synthetic compound promotes death of lung-cancer cells, tumors

DALLAS Nov. 12, 2007 Human lung-cancer tumors grown in mice have been shown to regress or disappear when treated with a synthetic compound that mimics the action of a naturally occurring death-promoting protein found in cells, researchers at UT Southwestern Medical Center report. The findings...

Scientists find how amber becomes death trap for watery creatures

GAINESVILLE, Fla. Shiny amber jewelry and a mucky Florida swamp have given scientists a window into an ancient ecosystem that could be anywhere from 15 million to 130 million years old. Scientists at the University of Florida and the Museum of Natural History in Berlin made the landmark discov...

Study by NTU professors provides important insight into apoptosis or programmed cell death

A study by Nanyang Technological University (NTU)'s Assistant Professor Li Hoi Yeung, Assistant Professor Koh Cheng Gee and their team have made an important contribution to the understanding of the process that cells go through when they die. This process known as 'apoptosis' or programmed cell d...

Common gene variants influence risk factor for sudden cardiac death

A new study has identified several common genetic variants related to a risk factor for sudden cardiac death. The report receiving early online release in the journal Nature Genetics identifies variants in genes, some known and some newly discovered, that influence the QT interval measured on th...

Genetic risk factors identified for sudden cardiac death

Building on these findings, the Helmholtz scientists and their clinical partners want to obtain further insights into the pathogenesic mechanisms of the disease and gain perspectives for early diagnosis and therapy. The results of the genome-wide study have been published online in the journal Na...

Hopkins scientists ID 10 genes associated with a risk factor for sudden cardiac death

One minute, he's a strapping 40-year-old with an enviable cholesterol level, working out on his treadmill. The next, he's dead. That an abnormality in his heart's electrical system had managed to stay on the Q.T. until it proved lethal is characteristic of sudden cardiac death, which an...

Ten genes identified in connection with sudden cardiac death

ANN ARBOR, Mich.---You're sitting at your desk and suddenly your heart is beating in overdrive or worse, lurching along like a car on fumes. It is a shocking, uncomfortable and frightening sensation. Irregular heart rhythms are a common cause of sudden cardiac death or SCD, a condition that ac...

Jefferson scientists discover a key protein regulator of inflammation and cell death

(PHILADELPHIA) Reporting in the journal Nature , researchers led by Emad Alnemri, Ph.D., professor of Biochemistry and Molecular Biology in the Kimmel Cancer Center at Jefferson, discovered a key protein component involved in inflammation. The protein, AIM2 (absent in melanoma 2), is involved...

Study helps explain connection between sleep apnea, stroke and death

BETHESDA, Md. (Jan. 6, 2009) − Obstructive sleep apnea decreases blood flow to the brain, elevates blood pressure within the brain and eventually harms the brain's ability to modulate these changes and prevent damage to itself, according to a new study published by The American Physiological...

Pores open the door to death

This press release is available in German . Our body is almost constantly being threatened by pathogens and cancerous cells that appear out of the blue. But the body puts up a fight: specialized cells in the immune system smuggle small molecules (granzymes) into cancer cells and those body...

When following the leader can lead into the jaws of death

For animals that live in social groups, and that includes humans, blindly following a leader could place them in danger. To avoid this, animals have developed simple but effective behaviour to follow where at least a few of them dare to tread rather than follow a single group member. This ...

Coral reefs and climate change: Microbes could be the key to coral death

Coral reefs could be dying out because of changes to the microbes that live in them just as much as from the direct rise in temperature caused by global warming, according to scientists speaking today (Wednesday 2 April 2008) at the Society for General Microbiologys 162nd meeting being held this w...

Marsupial lion tops African lion in fight to death

Pound for pound, Australias extinct marsupial lion (Thylacoleo carnifex) would have made mince meat of todays African lion (Panthera leo) had the two big hyper-carnivores ever squared off in a fight to the death, according to an Australian scientist. New research published in the Journal of Zoo...

Bleeding, not inflammation, is major cause of early lung infection death

Researchers believe they have discovered why a bacterial lung infection is so lethal in the early stages, and its not what medical authorities had thought, according to research published August 23 in the journal Immunity. The study reveals for the first time that a toxin released by bacteria caus...

Common cancer gene sends death order to tiny killer

Scientists at Johns Hopkins have discovered one way the p53 gene does what it's known for—stopping the colon cancer cells. Their report will be published in the June 8 issue of Molecular Cell. The research team identified a tiny bit of genetic code, a microRNA called miR-34a that participates i...

Experts predict Tamiflu could halve the pandemic influenza death toll versus no intervention

Treatment with the oral antiviral Tamiflu (oseltamivir) and prophylaxis for people exposed to infected patients could be one of the most cost-effective strategies for reducing illness and death during an influenza pandemic. According to modelling research presented by Beate Sander, University of T...

'Nurse cells' make life and death decisions for infection-fighting cells

"Nurse cells" play an important role in deciding which developing infection-fighting cells, called T cells, live and which die, according to research funded by the National Science Foundation (NSF) and reported in the June issue of the journal Experimental Biology and Medicine. The infection-fig...

Double the death rate from cirrhosis for 'blue collar' men

School of Population Health Professors Jake Najman and Gail Williams and Stockholm University's Professor Robin Room examined death rates among Australian men from liver cirrhosis between 1981 and 2002. Their results were published in the May 2007 edition of the prestigious journal, Drug and Alc...

High-dose anticlotting drug cuts heart attack, death risk in half

Pretreatment with double-dose anticlotting medication just before percutaneous coronary intervention (PCI) cuts the combined risk of heart attack and cardiac death by half, according to a study reported at the 30th Annual Scientific Sessions of the Society for Cardiovascular Angiography and Interve...

Glucose triggers brain cell death in rats after hypoglycemic coma

Brain damage that was thought to be caused by hypoglycemic coma actually occurs when glucose is administered to treat the coma, according to a study in rodents led by researchers at the San Francisco VA Medical Center. The results are surprising, say the authors, and may be of clinical significa...

Massive coral death attributed to earthquake

Scientists have reported what is thought to be one of the world’s greatest mass death of corals ever recorded as a result of the earthquake in Aceh, Indonesia on 28 March 2005. The recent survey by scientists from the Wildlife Conservation Society - Indonesia Program and the Australian Research C...

Massey researchers induce cell death in leukemia

Researchers from the Virginia Commonwealth University Massey Cancer Center today presented preclinical research at the American Association of Cancer Research's annual meeting suggesting the potential of a new combination treatment for chronic lymphocytic leukemia (CLL). In this study, led by S...
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