Culture in Biological News

InVitria to Unveil Powerful Cell Culture Media Component ZAP-CHO

InVitria’s BioProcess Theater presentation, “New Strategies for Optimizing CHO Performance,” to feature new supplement for CHO cell culture optimization called ZAP-CHO during BIO 2009 International Convention in Atlanta, GA.  Fort Collins, CO May 19, 2009 / b3c newswire ...

ExcellGene and Khner achieved milestone in development of novel 250 Liter mammalian cell culture bioreactors

May 12, 2009 / b3c newswire / - ExcellGene SA, Monthey and Adolf Kühner AG, Birsfelden announce today that they achieved an important milestone in the development of a revolutionary cell culture technology for scale up and manufacturing from suspension cultured mammalian cells. As part of a...

Primate culture is just a stone's throw away from human evolution, study finds

For 30 years, scientists have been studying stone-handling behavior in several troops of Japanese macaques to catch a unique glimpse of primate culture. By watching these monkeys acquire and maintain behavioral traditions from generation to generation, the scientists have gained insight into the c...

Cold Spring Harbor Protocols features organ and cell culture methods

COLD SPRING HARBOR, N.Y. (Mon., Nov. 3, 2008) Understanding the function of organs like the brain, kidney, and reproductive tissues requires experimental systems that allow for the study and manipulation of developing cells and tissues in the laboratory. This month's issue of Cold Spring Harb...

Reversible 3-D cell culture gel invented

Singapore's Institute of Bioengineering and Nanotechnology (IBN), which celebrates its fifth anniversary this year, has invented a unique user-friendly gel that can liquefy on demand, with the potential to revolutionize three-dimensional (3D) cell culture for medical research. As reported in N...

MIT: Culture influences brain function

CAMBRIDGE, Mass. - People from different cultures use their brains differently to solve the same visual perceptual tasks, MIT researchers and colleagues report in the first brain imaging study of its kind. Psychological research has established that American culture, which values the individual...

Thumb-size microsystem enables cell culture and incubation

Integrating silicon microchip technology with a network of tiny fluid channels, some thinner than a human hair, researchers at The Johns Hopkins University have developed a thumb-size micro-incubator to culture living cells for lab tests. In a recent edition of the journal IEEE Transactions on ...

Novel 3-D cell culture model shows selective tumor uptake of nanoparticles

A nanoparticle drug delivery system designed for brain tumor therapy has shown promising tumor cell selectivity in a novel cell culture model devised by University of Nottingham scientists. The project, conducted jointly in the Schools of Pharmacy, Biomedical Sciences and Human Development, will b...

Songbird study from CSHL, CCNY provides concrete measure of biology's impact on culture

Cold Spring Harbor, NY During infancy, each of us emerges from a delightful but largely incoherent babble of syllables and learns to speak normally, in the language of those who care for us. But imagine what would happen if we were somehow raised in utter isolation from other people, not only o...

Wonderful cheese is all in the culture

It's an age-old tradition that dates back at least 8,000 years but it seems we still have much to learn about the bacteria responsible for turning milk into cheese. Now an international research team led by Newcastle University has identified a new line of bacteria they believe add flavour to som...

Stem cell identity in culture may strongly depend on the cellular microenvironment

Identification, isolation and large scale culture of stem cells for potential medical applications is a major challenge in cell biology. In an upcoming PLoS ONE paper, researchers, including Andras Paldi, in Genethon (Evry, France) report, on the basis of experimental observations and computer simu...

New evidence of 'human' culture among primates

Fresh evidence that suggests monkeys can learn skills from each other, in the same manner as humans, has been uncovered by a University of Cambridge researcher. Dr Antonio Moura, a Brazilian researcher from the Department of Biological Anthropology, has discovered signs that Capuchin monkeys in B...

New culture method for hepatitis C virus uses primary hepatocytes and patient serum

Researchers open the way for improved study of hepatitis C virus by devising a novel virus culture system that allows replication of patient-isolated virus in nontransformed hepatocytes, instead of culture-adapted virus strains in transformed cell lines. The related report by Lázaro et al, "Hepati...

Cancer related gene p53 not regulated as indicated by previous tissue culture research

The cellular cascade of molecular signals that instructs cells with fatally damaged DNA to self-destruct pivots on the p53 tumor suppressor gene. If p53 is inactivated, as it is in over half of all human cancers, checks and balances on cell growth fail to operate, and body cells start to accumulate...

Scientists rid stem cell culture of key animal cells

Tackling a pressing and controversial technical barrier in stem cell biology, scientists at the WiCell Research Institute and the University of Wisconsin-Madison have crafted a recipe that allows researchers to grow human embryonic stem cells in the absence of mouse-derived "feeder" cells, long tho...

'Microfluidic palette' may paint clearer picture of biological processes

... distinctly different from any other location. Similarly, if three separate drugs were injected into the palette where the microchamber contained a culture of cells, individual cells at different locations in the chamber would be exposed to different combinations of the drugs. In a single experiment, one ...

Reprogramming human cells without inserting genes

...from the journal Cloning and Stem Cells . "We show that by manipulating culture conditions alone, we can achieve changes in fibroblasts that would be benef...to, and by adding a protein called fibroblast growth factor 2 (FGF2) to the culture medium. (FGF2 is a naturally occurring protein that is known to be vital fo...

Study shows cancer vaccines led to long-term survival for patients with metastatic melanoma

...y for five months for a total of up to eight injections. The patient's dendritic cells were obtained from their peripheral blood and mixed with a cell culture of the patient's own melanoma cells that had been self-renewing and proliferating in the laboratory. The patient-specific vaccine is designed to stimu...

IOS Press announces launch of Journal of Berry Research

...: from genetics to variety evaluation; nursery productions systems and plant quality control; plant physiology, biochemistry and molecular biology and culture management; and health for consumers (components and factors affecting the nutritional value of berries). Specifically, the Journal will cover berr...

Researchers design first model motor nerve system that's insulated and organized like the human body

...ong with demyelination". Hickman's team has now achieved the first successful model nodes of Ranvier formation on motor nerves in a defined serum-free culture system. Researchers have long recognized the need for lab-grown motor nerve cells that myelinate and form nodes of Ranvier in order to use control...

Playing it safe

...hese stem cells have the capacity to generate all types of body tissue. The culture conditions alone were the crucial factor behind the success of the reprogra...Each time we filled around 8000 cells into the individual wells of the cell culture plates, some of the cells reprogrammed themselves after two weeks," reports...

Chromosomal problems affect nearly all human embryos

... young, normal fertile couples. This leads us to believe that such abnormalities must be present in all human IVF-ICSI embryos. "Although in vitro culture conditions are known to have a limited influence on the rate of chromosomal imbalances in IVF/ICSI embryos, it is probable that the chromosome instabi...

Kelvin Lee winner of Biochemical Engineering Journal Young Investigator Award

...se, the production of protein-based therapeutics and the development of technologies for protein analysis. He is the chair of the upcoming ECI Cell culture Engineering XII Conference. ...

Female human embryos adjust the balance of X chromosomes before implantation

... before implantation and this could have possible implications for in vitro culture such as during IVF treatment. Furthermore, our research shows that X chromo... pre-implantation stage, further research should be able to clarify whether culture conditions in the laboratory influence the growth rate and survival of fema...

'The Vision Revolution': Eyes are the source of human 'superpowers'

...h a unique, interdisciplinary perspective. A self-described "square, stick-in-the-mud, pencil-necked scientist," he employs humor, a sprinkling of pop culture references, and intuitive everyday analogies to paint a rich picture of leading-edge theoretical neuroscience and evolutionary biology. From asking...

UCLA cancer researchers develop model that may help identify cancer stem cells

...ultures in vitro with high efficiency using the novel strategy that utilized an autologous tumor microenvironment," the study states. "In this primary culture model, we have been able to provide proof-of-concept that candidate lung cancer stem cells are present, that candidate lung cancer stem cells can be m...

First ever worldwide census analysis of caribou/reindeer numbers reveals dramatic decline

...depend on the animals for their livelihood. "In this research we tried to look beyond the science and focus also on the impact on the economies and culture of northern people," said Vors. The dramatic changes caused by global warming that happen in the Arctic and which impact on the herds include; earl...

Hatchery fish may hurt efforts to sustain wild salmon runs

...roblem, but it was just that type of hatchery fish that were used in the Hood River study. This demonstrates that even a single generation of hatchery culture can still have strong effects. Although this study was done with steelhead trout, it would be reasonable to extrapolate its results to other salmon...

MU study finds connection between evolution, classroom learning

...more group and social interactions to teach topics that can be challenging. "From an evolutionary perspective, what we are designed to do and what culture says we now have to do, is very different," Geary said. "We should not expect what comes naturally to us to be the best way to learn something new." ...

InVitria Sponsors ESACT 2009 in Dublin, Ireland

..., a leading supplier of performance enhancing cell culture media supplements, to sponsor the 21st Meeting of ...ees the powerful effects of its portfolio of cell culture media supplements developed to solve the regulato...uct called ZAP-CHO , a performance enhancing cell culture media supplement designed to improve cell growth a...

Genetically corrected blood cells obtained from skin cells from Fanconi anemia patients

...rentiating iPS cells towards healthy tissues these patients lack. The generation of blood cells in this research was carried out in vitro, in cell culture plates, which places the research in a preclinical environment. It remains unknown whether they would generate blood cells after being transplanted. M...

Capturing the birth of a synapse

...nked to autism. The discovery -- captured with fluorescent imaging of excitatory neurons harvested from rat pups shortly after birth and studied in culture as they continued to develop -- is described in a paper placed online May 18 ahead of formal publication in the open-access journal Neural Developmen...

ExcellGene SA first company to offer contract manufacturing in 250 Liter OrbShake bioreactor

...logies for the production of recombinant proteins from mammalian cells in bioreactors. As a service company, ExcellGene generates entire upstream cell culture processes for its customers, from DNA to scalable manufacturing under cGMP. Additionally, the company provides protein production services, based both...

New lead on malaria treatment

...cells, fumarranol stuck to PfMetAP2 and stopped it from working. They next asked whether fumarranol could stop malaria parasites from growing in a culture dish. They treated both drug-resistant and multidrug-resistant strains of Plasmodium falciparum and found that fumarranol could stop the parasite from...

SRI International to screen drugs that fight 2009 H1N1 influenza A

...nce with all guidelines prescribed by the Centers for Disease Control and Prevention (CDC) for handling this strain of influenza. SRI researchers will culture cell lines and study H1N1 virus growth under well-controlled conditions. Next, they will begin testing the first round of drugs. Assuming that some dr...

Grasslands: The future of sustainable agriculture

...ard agriculturists, students, the public, and policy makers. Wendell Berry, a farmer and renowned author of more than forty books and essays about culture and agriculture, provides a moving foreword for the book that stresses the importance of properly educating future farmers about the land and the role...

No insurance? No colonoscopy

...have proven to raise the number of patient intention to get screened, helping to overcome socio-economic barriers. While recognising that language, culture and economic inequality remain significant barriers, Inadomi is optimistic about "the use of new technology and techniques for disseminating informati...

New early detection studies of lung cancer in non-smokers launched today

...ditional collaborators from the EDRN. The NCI-EDRN will fund most of the tumor studies, and the Canary Foundation will provide funding for the cell culture studies. Projects funded by NCI include: Protein biomarker discovery: In-Depth Proteomic Analysis of Plasmas from Subjects with Lung Cancer Ar...

When cells reach out and touch

...amount they found in isolated cells growing in culture. To investigate, the team grew cancer cells and non-cancer cells to increasing densities in culture and, using a tool developed in the Mendell laboratory, measured the abundance of hundreds of microRNAs simultaneously. This analysis revealed that the...

Genetic secrets of date palm unlocked by researchers at Weill Cornell Medical College in Qatar

...m gene by about 1,000 fold." Mr. Malek and his research assistants obtained the DNA from leaves of the date palm provided by the Qatar Plant Tissue culture Lab in the Department of Agriculture and Water Research (Qatar Ministry of Municipal Affairs and Agriculture). Date palm trees play a significant r...