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Connections in Biological News

Calculating gene and protein connections in a Parkinson's disease model

FINDINGS: Researchers have created an algorithm that meshes existing data to produce a clearer step-by-step flow chart of how cells respond to stimuli. Using this new method, Whitehead Institute and Massachusetts Institute of Technology scientists have analyzed alpha-synuclein toxicity to identify...

Study finds connections between genetics, brain activity and preference

A team of researchers from Massachusetts General Hospital (MGH) has used brain imaging, genetics and experimental psychology techniques to identify a connection between brain reward circuitry, a behavioral measurement of preference and a gene variant that appears to influence both. The report in ...

Scientists discover a molecular scaffold that guides connections between brain cells

Brain cells known as neurons process information by joining into complex networks, transmitting signals to each other across junctions called synapses. But neurons dont just connect to other neurons, emphasizes Z. Josh Huang, Ph.D., in a lot of cases, they connect to very specific partners, at par...

Specific brain protein required for nerve cell connections to form and function

CHAPEL HILL Neurons, or nerve cells, communicate with each other through contact points called synapses. When these connections are damaged, communication breaks down, causing the messages that would normally help our feet push our bike pedals or our mind locate our car keys to fall short. Now...

Computer with brain connections changing quality of life of paralyzed

Fundamental theories regarding consciousness, emotion and quality of life in sufferers of paralysis from Amyotrophic Lateral Sclerosis (ALS, also known as 'Lou Gerhig's disease') are being challenged based on new research on brain-computer interaction. ALS is a progressive disease that destroys neu...

On the track of tiny larvae, a new model elucidates connections in marine ecology

A computer model newly developed by researchers combines ocean current simulations and genetic forecasting to help scientists predict animal dispersion patterns and details of the ecology of coral reefs across the Caribbean Sea. The work is reported by Heather M. Galindo and Stephen R. Palumbi of S...

New study identifies key gene in development of connections between brain and spinal cord

A new study, presented at the American College of Neuropsychopharmacology's (ACNP) Annual Meeting, has identified a specific gene that is necessary for the development of connections between the brain and the spinal cord. This research, conducted by Stanford University through a grant from the Na...

Mapping neuron connections in the brain

The human brain contains from 10 to 100 billion neurons, and each has hundreds of connections with neighboring neurons. Making sense of these intricate connections is essential to understanding brain function, and the task is a monumental one. Thanks to a new theoretical approach to mapping neuro...

Brain difference in psychopaths identified

...und differences in the brain which may provide a biological explanation for psychopathy. The results of their study are outlined in the paper 'Altered connections on the road to psychopathy', published in Molecular Psychiatry . The research investigated the brain biology of psychopaths with convictions that ...

Researchers develop 'brain-reading' methods

...ng tasks have their own distinct pattern of neural connections stretching across the brain, similar to the finger...er, the brain is able to arrange and rearrange the connections based on the mental task being undertaken. "You... than that. It has the ability to rearrange neural connections for different functions. By examining the pattern ...

DOE-funded research projects win 46 R&D 100 Awards for 2009

... Lasonix A new approach for fabricating insulators, semiconductors, and metallic conductors to form standard semiconductor microcircuits, metallic connections and pathways, and vertically integrated circuits. The Artificial Retina Project see Lawrence Livermore National Lab National Energy Techn...

The value of variation: Ecologists consider the causes and consequences

...spects of the Working Group is its interdisciplinary approach involving both biologists and mathematicians to studying the issue. "By establishing connections between these usually separate fields, we hope to initiate a new field of mathematical ecology that melds genetics, evolution, and dynamic foraging be...

Music is the engine of new U-M lab-on-a-chip device

...ten use dozens of air hoses, valves and electrical connections between the chip and a computer to move, mix and s...rs replaces these air hoses, valves and electrical connections with what are called resonance cavities. The reson...lever system," Burns said. "It's a way to make the connections between the microfluidic world and the real world ...

University of Miami receives stimulus funds for study of hurricane impacts on structures, ecosystems

... affect the distribution of marine organisms and their connectivity. The Center will also offer opportunities for collaborations in understanding the connections between the oceans and human health including studies of harmful algal blooms, the effects of toxins in the marine environment as well as developing a...

NIH expands Human Microbiome Project; funds sequencing centers and disease projects

...ive tract: Pediatric Irritable Bowel Syndrome (IBS) $750,000 This project will examine the composition of the intestinal microbiome and any possible connections with irritable bowel syndrome in children. Gary D. Wu, M.D., University of Pennsylvania School of Medicine, Philadelphia Digestive tract, Crohn'...

American Chemical Society's Weekly Presspac -- June 17, 2009

...ther information. From Chemical Abstracts Service (CAS) CAS Science connections is a series of articles that showcases the value of CAS databases in ligh...anging in topics from fruit flies to Nobel Prize winners, the CAS - Science connections series points to the CAS databases for a more complete understanding of...

Scientists capture the first image of memories being made

...arch has focused on synapses which are the main site of exchange and storage in the brain. They form a vast but also constantly fluctuating network of connections whose ability to change and adapt, called synaptic plasticity, may be the fundamental basis of learning and memory. "But, if this network is const...

UC Davis researchers visualize formation of a new synapse

...he study show that, indeed, the two synaptic receptor proteins, PSD-95 and NMDA, are independently recruited to the site of synapse formation once the connections are locked in place by neuroligin. "Synapses are basically specialized sites of cell adhesion that are initially formed during development of the n...

TRAPping proteins that work together inside living cells

...cientists start with a familiar one and use it as bait to find others that work alongside it. To pin down the collaborators, researchers make physical connections between old and new proteins with chemicals called crosslinkers. The sticky crosslinkers will only connect proteins close enough to work together, the...

Huntington's disease deciphered

...huttles proteins from the cell body where they are synthesized to the synaptic terminals where they are needed. A neuron's critical role in making connections may require it to make the cellular trunk, called an axon, between the cell body and the synaptic terminal to be very long. Some cells have axons that...

Isolated forest patches lose species, diversity

...ry soon by nearby populations of the same species. That's what does not happen once a habitat becomes isolated or that patch becomes smaller." The connections between local plant communities and more distant landscapes have increased markedly. The bottom line is that humans appear to be having larger cumulat...

American Chemical Society's Weekly PressPac -- June 3, 2009

...ther information. From Chemical Abstracts Service (CAS) CAS Science connections is a series of articles that showcases the value of CAS databases in ligh...anging in topics from fruit flies to Nobel Prize winners, the CAS - Science connections series points to the CAS databases for a more complete understanding of...

Protein linked to mental retardation controls synapse maturation, plasticity, CSHL team finds

...ed mental retardation. Indeed, problems at the synapse -- in their formation and in the mechanisms through which the strength, or plasticity, of their connections are regulated -- are thought to contribute to numerous mental and neurological disorders. "Great progress has been made in recent years in the iden...

American Chemical Society's Weekly PressPac -- May 20, 2009

...ther information. From Chemical Abstracts Service (CAS) CAS Science connections is a series of articles that showcases the value of CAS databases in ligh...anging in topics from fruit flies to Nobel Prize winners, the CAS - Science connections series points to the CAS databases for a more complete understanding of...

American Chemical Society's Weekly PressPac -- May 13, 2009

.../glossary.shtml From Chemical Abstracts Service (CAS) CAS Science connections is a series of articles that showcases the value of CAS databases in ligh...anging in topics from fruit flies to Nobel Prize winners, the CAS - Science connections series points to the CAS databases for a more complete understanding of...

Identification of a key molecular pathway required for brain neural circuit formation

...e ability of Shh to guide axons. Connecting axons with an appropriate set of targets is very complex. Inappropriate wiring or damage to these neuronal connections leads to severe abnormalities of the nervous system. "Knowing the effectors of axon guidance molecules such as Shh", adds Dr. Charron, "helps us to un...

Preclinical work shows how one gene causes severe mental retardation

...at neurons in the brain can form and adjust their connections to other neurons for storing sensory information....ce were deprived of sensory stimulation, the brain connections could be recovered, a finding that indicated a pha...ver their lifetime. "When we have experiences, connections between brain cells are modified so that we can le...

UAB professor receives HudsonAlpha Innovation Prize

...Alpha prize committee received its recommendations from a distinguished and impartial group of scientists who reside outside the state and who have no connections to participating universities. Funding for the annual HudsonAlpha Prize for Outstanding Innovation in Life Sciences is provided through a grant by ...

Neuroscientists discover long-term potentiation in the olfactory bulb

... be published in the June 2009 issue of Nature Neuroscience and is currently available online. In the 1970s, scientists discovered that elemental connections between brain cells, called synapses, could change their strength following brief periods of activity. This process, called long-term potentiation (LT...

Wildlife trade threatens public health and ecosystems

...ood supply chains and human health. "As our world, in many senses, grows smaller and smaller with the ease of international travel, the network of connections has increased, facilitating the spread of diseases," said Rita Teutonico, senior advisor for integrative activities in the National Science Foundation...

People of higher socioeconomic status choose better diets -- but pay more per calorie

...itious diets may provide one explanation for these observations. Future studies, based on more representative samples, will be needed to elucidate the connections between diet quality and diet cost across socioeconomic strata." ...

American Chemical Society's Weekly PressPac -- April 22, 2009

.../glossary.shtml From Chemical Abstracts Service (CAS) CAS Science connections is a series of articles that showcases the value of CAS databases in ligh...anging in topics from fruit flies to Nobel Prize winners, the CAS - Science connections series points to the CAS databases for a more complete understanding of...

Details of bacterial 'injection' system revealed

...dual subunits and their angular orientation, which changes direction over the structure's length. We now see 12-fold symmetric features and details of connections between sub-domains both internally and externally throughout the 'needle' base." The more accurate model therefore shows how the different parts o...

ASBMB Annual Meeting to feature talks on the biochemistry of aging

...e secrets of longevity may still be a long time away, the presentations at ASBMB illustrate that we are at least beginning to understand the intricate connections between diet, metabolism, aging, and disease. Some of these aging-related presentations include: Regulation of Obesity, Heart Function, and Li...

American Chemical Society Weekly PressPac -- April 8, 2009

...101/glossary.shtml From Chemical Abstracts Service (CAS) CAS Science connections is a series of articles that showcases the value of CAS databases in ligh...anging in topics from fruit flies to Nobel Prize winners, the CAS - Science connections series points to the CAS databases for a more complete understanding of...

American Society for Microbiology to host 109th general meeting in Philadelphia

...al activities and genomes into the energy grid New concepts and strategies for vaccines Updates on MRSA. Is nasal screening alone enough? The connections between human, animal and environmental health Latest research on the human microbiome and how the bacteria in our system affect our health for bet...

Humans may be losers if technological nature replaces the real thing

...animals in their natural habitat, hiking the John Muir Trail or a playing with a live pet? Modern technology increasingly is encroaching into human connections with the natural world and University of Washington psychologists believe this intrusion may emerge as one of the central psychological problems of ou...

Cancer Genomics Browser gives cancer researchers a powerful new tool

...signaling pathways are--all organized by, say, how well each patient responded to a particular drug. As a result, the process of identifying possible connections is really easy." The browser was developed by a team of scientists at UCSC's Center for Biomolecular Science and Engineering (CBSE), an interdiscip...

Exploring the dynamic relationship between health and environment

...w choices and decisions can be made when both human and environmental health are at stake. Andrew P. Dobson, Princeton University, will talk about the connections among biodiversity, disease transmission, and human health. This keynote will lead into talks by Michael J. Balick (New York Botanical Gardens), Patri...

Stem cells replace stroke-damaged tissue in rats

...les can be injected through a very fine needle and then adopt the precise shape of the cavity. In this process the cells fill the cavity and can make connections with other cells, which helps to establish the tissue. "Over a few days we can see cells migrating along the scaffold particles and forming a primi...
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