Clinical in Biological News

$20 million NIH grant to transform clinical research at UIC

The National Institutes of Health has awarded a five year $20 million grant to the University of Illinois at Chicago's Center for Clinical and Translational Science. The grant is the largest in UIC's history. "The CCTS draws upon the rich intellectual breadth of the UIC campus and adds to th...

Systems biology recommended as a clinical approach to cancer

Blacksburg, Va. -- Four researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech and their colleagues at the Wake Forest University School of Medicine are advocating the use of systems biology as an innovative clinical approach to cancer. This approach could result in the develo...

Funxional successfully completes initial clinical trial of FX125L, an anti-inflammatory drug with a novel mechanism of action

CAMBRIDGE (UK). 8th July 2009 / b3c newswire / - Funxional Therapeutics Ltd (Funxional) has announced today the successful completion of the first Phase I study with FX125L , an orally available small molecule which belongs to a new therapeutic class named Broad Spectrum Chemokine Inhibitors ( BS...

Brain-computer interface, developed at Brown, begins new clinical trial

PROVIDENCE, R.I. [Brown University] BrainGate, an investigational technology being developed to detect brain signals and to allow people with paralysis to use those signals to control assistive devices, is about to begin a second, larger clinical trial. The system is based on neuroscience, engine...

SNM's clinical trials network gains added support from industry leader

Reston, Va.The SNM Clinical Trials Network, an initiative designed to address the need for streamlined drug discovery through the integration of imaging biomarkers into multi-center clinical trials, recently added Genentech, Inc. as a supporter. SNM, the world's largest medical and scientific s...

Creating ideal neural cells for clinical use

LA JOLLA, Calif., April 13, 2009 -- Investigators at the Burnham Institute for Medical Research (Burnham) have developed a protocol to rapidly differentiate human embryonic stem cells (hESCs) into neural progenitor cells that may be ideal for transplantation. The research, conducted by Alexei Ters...

NIH Clinical and Translational Science Consortium grows to 39 members

The National Institutes of Health announced today that the University of Cincinnati will become the 39th member of its Clinical and Translational Science Award (CTSA) consortium. Led by the National Center for Research Resources (NCRR), part of the NIH, this national network of medical research in...

UC Davis bench-to-bedside research: Promising treatment in clinical trials

DAVIS, CALIF.A new drug developed at the University of California, Davis to treat diabetes, hypertension and inflammatory has entered Phase II of human clinical trials to evaluate its efficacy. The compound, a soluble epoxide hydrolase enzyme (s-EH) inhibitor, is "a first-in-class drug which m...

Researchers win award for best clinical paper in orthopedic physical therapy

University of Delaware researchers have won the American Physical Therapy Association's award for the best clinical paper in orthopedics published in 2008. Their study focused on one of the most controversial topics in sports medicine-the management of anterior cruciate ligament (ACL) injuries....

ABC publishes monograph on scientific and clinical research of Sinupret

Austin, Texas (February 5, 2009) The nonprofit American Botanical Council (ABC) has just published a monograph summarizing the scientific and clinical studies of Sinupret, a clinically-tested herbal combination for upper respiratory tract health, including conditions associated with sinusitis and ...

TGen Clinical Research Services at Scottsdale Healthcare and Mayo Clinic study new cancer drug

SCOTTSDALE, Ariz. Jan. 29, 2008 TGen Clinical Research Services (TCRS) at Scottsdale Healthcare and Mayo Clinic are testing a new drug that may offer broad potential to treat solid tumors. Clinical trials of the drug TH-302 are being conducted at TGen Clinical Research Services at Scottsdale...

3 new informatics pilot projects to aid clinical and translational scientists nationwide

The National Institutes of Health (NIH) has awarded three contracts for pilot projects to improve informatics support for researchers conducting small- to medium-sized clinical studies. Each of the two-year contracts, which will total up to an estimated $4 million, represents a collaboration among...

Genome Medicine: Bridging the gap between research and clinical practice

Today, BioMed Central's premier open access medical journal Genome Medicine has officially launched with the publication of its January 2009 issue. Genomic medicine is at the leading edge of medical advances and is one of fastest growing areas of biomedical research. Our growing understanding...

Far-reaching genetics topics to be addressed: 2009 Annual Clinical Genetics Meeting, March 25-29

The American College of Medical Genetics (ACMG) will hold its 16th Annual Clinical Genetics Meeting from Wednesday, March 25 through Sunday, March 29, 2009 at the Tampa Convention Center. Clinical and medical genetics and its integration into healthcare is evolving at a dizzying pace and the 20...

In just 5 years, gene discovery to clinical trial of potential treatment

One of the fastest translations of a basic research discovery into a promising clinical trial for an "untreatable" and fatal disorder will be discussed publicly for the first time by the key players in this remarkable research story, on Sunday, Dec. 14, at the American Society for Cell Biology (AS...

New book helps medical students master clinical skills

COLD SPRING HARBOR, N.Y. (Nov. 12, 2008) For medical students who spend years studying textbooks in preparation for written exams on theoretical concepts, it can be rather intimidating to prepare for a test on practical skills used in the clinic. The third edition of a best-selling book that h...

Biochemistry of human physiology in health and disease is focus of updated clinical text

COLD SPRING HARBOR, N.Y. (Nov. 4, 2008) To intelligently perform laboratory methods in the investigation and diagnosis of disease, a solid understanding of the biochemistry behind the diseases and methods is required. The second edition of a leading book that describes the biochemical and phys...

A new journal where molecular biology meets clinical research

Heidelberg 09 October 2008 The European Molecular Biology Organization (EMBO) proudly announces the introduction of EMBO Molecular Medicine , a new journal dedicated to a research discipline focused on the interface between molecular biology and clinical research. The new journal, launching in 2...

JDRF-funded clinical trial demonstrates continuous glucose monitoring improves blood sugar control

NEW YORK, September 8, 2008 Patients with type 1 diabetes who used continuous glucose monitoring (CGM) devices to help manage their disease experienced significant improvements in blood sugar control, according to initial results of a major multicenter clinical trial funded by the Juvenile Diabet...

New study spotlights National Institutes of Health grant outcomes for clinical research

Although the need to translate basic science discoveries into the clinical arena is widely acknowledged, a new study by researchers at the Medical College of Wisconsin, in Milwaukee, and National Institutes of Health (NIH) identified reasons why clinical science grant applications receive less p...

NCI grant launches clinical trials for colon cancer screening

EVANSTON, Ill. --- A Northwestern University biomedical engineer who has developed optical technology shown to be effective for the early detection of colon cancer has received a $7.5 million grant over five years from the National Cancer Institute to further study an instrument that potentially c...

Florida researchers receive JDRF 'Excellence in Clinical Research Award'

Washington, DC, June 13, 2008 Mary Tyler Moore, the Juvenile Diabetes Research Foundation's international chairman, and her husband, S. Robert Levine, M.D., presented the sixth annual "Excellence in Clinical Research Award" to a team of Florida scientists at JDRF's annual conference today in Wash...

A nutritional supplement could improve the clinical situation of ICU patients

This release is available in Spanish . Scientists from the University of Granada and the Virgen de las Nieves Hospital have found out that some critical patients could improve their oxide stress and, consequently, their clinical situation by taking a simple exogenous antioxidant treatment...

NIH expands national consortium dedicated to transforming clinical and translational research

Fourteen academic health centers in 11 states are the latest members of the National Institutes of Healths Clinical and Translational Science Award (CTSA) consortium. Creating a unique network of medical research institutions across the nation, the consortium is working to reduce the time it takes...

Peter J. McGuire, MB BCh, is awarded the 2008-2009 Genzyme/ACMGF Clinical Genetics Fellowship

Peter J. McGuire, MB BCh, of Mount Sinai Medical Center, New York was honored as the 2008-2009 recipient of the Genzyme/ACMGF Clinical Genetics Fellowship in Biochemical Genetics at the ACMG 2008 Annual Clinical Genetics Meeting in Phoenix, AZ. The objective of the Genzyme/ACMGF Award is to sup...

The Lancet publishes first clinical trial data of a fully bioabsorbable drug eluting stent

ABBOTT PARK, Ill., March 13, 2008 Data published today in The Lancet from ABSORB, the worlds first clinical trial of a fully bioabsorbable drug eluting stent for the treatment of coronary artery disease, demonstrated no stent thrombosis, no clinically driven target lesion revascularizations (re-t...

NHLBI issues first US von Willebrand Disease clinical practice guidelines

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health, today issued the first clinical guidelines in the United States for the diagnosis and management of von Willebrand Disease (VWD), the most common inherited bleeding disorder. The guidelines include recommen...

Simple screening questionnaire for kidney disease outperforms current clinical practice guidelines

NEW YORK (Feb. 28, 2007) -- The general public is not sufficiently aware that chronic kidney disease (CKD) is a serious and progressive medical condition. It remains under-diagnosed and under-treated. Understandably so, since in its early stages CKD is often asymptomatic, making individuals with t...

Nucleonics initiates hepatitis B clinical trial with expressed interfering RNA therapeutic

HORSHAM, PA (January 11, 2008): Nucleonics, Inc., a privately held biotechnology company focused on the development of novel RNA interference (RNAi)-based therapeutics, announced today that the company has begun treating patients in a Phase 1 human safety study of its experimental treatment for c...

New clinical trial results show how personalized medicine will alter treatment of genetic disorders

WASHINGTON, DC--One of the nations pre-eminent genetic researchers, Eric Hoffman, PhD, of Childrens Research Institute at Childrens National Medical Center, predicts that in relatively short order, medicines next innovation--individualized molecular therapies--will have the unprecedented ability t...

New clinical data shows chromium picolinate improves cognitive function

PURCHASE, N.Y., December 13, 2007 Nutrition 21, Inc. (NASDAQ: NXXI), a leading developer and marketer of chromium-based and omega-3 fish oil-based nutritional supplements, today announced the results of a clinical study that showed daily supplementation with 1000 mcg of chromium as chromium picol...

Study of African traditional medicine will begin world-first clinical trial

COLUMBIA, Mo. Described as a hotspot of botanical diversity, there are more than 20,000 indigenous plant species in South Africa. Several thousand of them are used by traditional healers every day in that country for treating a range of problems from the common cold to serious diseases such as AI...

Singulex Teams With Wyeth Pharmaceuticals to Translate Pre-Clinical Biomarker Research Into Clinical Study Design

HAYWARD, Calif., Nov. 27 /PRNewswire/ -- Singulex Inc. today announced that it is collaborating with researchers at Wyeth Research to develop immunoassays on the company's Erenna(TM) system. Singulex has installed the Erenna system at Wyeth as part of its Erenna Technology Access Program (ETAP...

Cleveland Clinic leading clinical program to improve early-stage lung cancer detection

Chicago, November 26, 2007 Cleveland Clinic and Riverain Medical today announced the establishment of the first study in an ongoing program to determine whether chest X-ray CAD (computer-aided detection) can improve practical early detection of lung cancer. The program is designed to determine w...

Phase 2 of Singapore's Biomedical Sciences Initiative gains momentum for clinical research

A new partnership to build an integrated neuroscience research programme that spans basic science all the way to clinical research. Strategic research infrastructure for tertiary hospitals and medical schools, and a national organisation to support and strengthen late phase clinical trials in Sin...

U of M begins nation's first clinical trial using T-reg cells from cord blood in leukemia treatment

University of Minnesota researchers have initiated a ground breaking clinical trial to determine the optimal dose and safety of T regulatory cells (T-regs) to decrease the risk of immune reactions common in patients undergoing blood and marrow transplantation. Ultimately, the researchers hope the...

First clinical trial of gene therapy for childhood blindness

The first clinical trial to test a revolutionary treatment for blindness in children has been announced by researchers at UCL (University College London). The trial, funded by the Department of Health, is the first of its kind and could have a significant impact on future treatments for eye disease...

30+ AIDS vaccine clinical trials in 24 countries, research occurring on every continent

The International AIDS Vaccine Initiative's (IAVI) January 2007 Annual Issue of VAX, an editorially independent bulletin on AIDS vaccine research published by IAVI, reports that 13 new preventive AIDS vaccine trials were initiated in eight countries around the world in 2006. There are now more than...

NIH announces phase III clinical trial of creatine for Parkinson's disease

The NIH National Institute of Neurological Disorders and Stroke (NINDS) today is launching a large-scale clinical trial to learn if the nutritional supplement creatine can slow the progression of Parkinson's disease (PD). While creatine is not an approved therapy for PD or any other condition, it ...

New malaria vaccine shows promise in early clinical trial

A malaria vaccine remains the most desired tool to combat the worsening malaria epidemic in many developing countries. Pierre Druilhe and colleagues (from the Institut Pasteur in Paris) have completed the first human trial of a vaccine based on MSP3, a protein present on the surface of the malaria ...