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Channel in Biological News

Opening a channel for salt retention

A research team has developed the first small molecule that can reversibly activate a key protein involved in balancing sodium levels, paving the way for drugs that can treat low blood pressure and related conditions. The human epithelial sodium channel (ENaC) controls sodium flow across many ...

Cells direct membrane traffic by channel width

For a glycerol molecule, a measly angstrom's difference in diameter is a road-closed sign: You can't squeeze through unless you are a sleek, water-molecule-sized sports car, say scientists at the University of Illinois at Urbana-Champaign. The roadway is in aquaporins, a class of proteins that fo...

Rodent size linked to human population and climate change

...century, are quite substantial. He had done earlier studies on a century's worth of anatomic changes between two geographically isolated rodents -- channel Island deer mice from coastal California and white-footed mice northwest of Chicago -- and noted fast change among both. "I suspected they weren't ...

'Microfluidic palette' may paint clearer picture of biological processes

...pe, but it could be moreallow various mixtures to flow into the chamber. Beneath the chamber, each access port connects to the long tail of a Y-shaped channel etched into a second layer. These channels deliver test chemicals to the chamber. Fluid flow in and out of the short arms of each Y at constant pressu...

University has grand designs to build a house of straw

...nology and Willmott Dixon. Some of the building has already appeared in the media spotlight. Last year the team helped Kevin McCloud, presenter of channel 4's Grand Designs programme, to build an eco-friendly house in six days using ModCell panels for the Grand Designs Live exhibition. All the wall ...

US-Mexico border wall could threaten wildlife species

...ctivity both people crossing and the border patrols seeking them has to have an effect on wildlife. "Gaps in the fence could help, but that might channel more people to use those open areas for crossing, negating the benefit for wildlife and the purpose for constructing the wall in the first place," he ...

Virus-resistant grapevines

...nt them from spreading in the plant and causing damage." To enable the plant to produce the antibodies, the scientists have to modify its genotype and channel genetic information for the antibodies into it. This task is performed by tiny helpers called agrobacteria, which genetic engineers have been using fo...

Researchers see evidence of memory in the songbird brain

...luded a lot of transcription factors that modulate the activity of other genes. Many other genes were downregulated, including those that code for ion channel proteins, which allow ions to flow into the cell. This could be one way that the brain dampens its response to a powerful stimulus, protecting itself ...

International collaboration by scientists culminates in novel ion channels database

...rmation for 8 VGIC and 3 LGIC families. Curation of the remaining five ion channel gene families is underway. The ion channel database is now available at: http://www.iuphar-db.org/IC/ReceptorFamilies...

RSA Designated as the Leader in One-Time Password Market by Frost & Sullivan

...rganization." "The RSA SecurID two-factor authentication system is used by over 40,000,000 people and is supported by thousands of technology and channel partners worldwide. As a result, RSA is well positioned to continue leading the way in helping organizations protect identities, infrastructures and i...

Enzyme doesn't act alone in atrial fibrillation

...9) An overactive enzyme is behind a leaky calcium channel that plays a role in the development of atrial fib...heart rates were raised, the mice with the calcium channel mutation had no signs of arrhythmia. Again the res... in the genetic code and stop the specific calcium channel from being affected by the enzyme. Further studies...

Discovery of the cell's water gate may lead to new cancer drugs

...can be opened and closed depending on how much water the cell must release or absorb. Computer simulations and biological experiments suggest that the channel is regulated with a combination of mechanical regulation and phosphorylation", says Karin Lindkvist. Similar to human Yeast cells are similar t...

Crustacean shell with polyester creates mixed-fiber material for nerve repair

...ts. For large gaps surgeons used to attempt a more difficult nerve graft. Current surgical practice is to attach tiny tubes, called nerve guides, that channel the two fragments toward each other. Today's commercial nerve guides are made from collagen, a structural protein derived from animal cells. But co...

New method separates cancer cells from normal cells

...led ratcheting, is a very tiny system of channels for cell locomotion. Each channel is less than a tenth of a millimeter wide. The asymmetric obstacles inside ...long and thin with long protrusions on the ends. The researchers designed a channel with "spikes" coming out at 45-degree angles from the walls, alternating on...

Researchers create freestanding nanoparticle films without fillers

... key component in the transistors in integrated circuits is an insulating layer that separates the gate, which turns current flow on and off, from the channel through which the current flows. Traditionally, semiconductor manufacturers have used silicon dioxide for this purpose. As transistors have shrunk, ho...

Researchers engineer metabolic pathway in mice to prevent diet-induced obesity

...ddressed," Liao said. "One is the regulation; fatty acid metabolism is highly regulated. The other is digestion of the fatty acid; there needs to be a channel to burn this fat." "We came up with an unconventional idea which we borrowed from plants and bacteria," said Jason Dean, a graduate student on L...

Striata and CIC Launch Integrated eSignature, eDelivery, and eBilling for the Financial Services Industry

...chose CIC's products to meet their needs. CIC has deployments with over 400 channel partners and enterprises worldwide representing hundreds of thousands of us...of paper. CIC sells directly to enterprises and through system integrators, channel partners and OEMs. CIC is headquartered in Redwood Shores, California and h...

New research helps explain how connexin hemichannels are kept closed

...tions regarding how they open in certain conditions as part of a junctional channel (1). As Harris explains, the gating mechanism that controls the opening...tion, the concurrent unveiling of a high-resolution structure of a connexin channel has been a long-awaited and noteworthy development (4). According to Ha...

Yale team identifies key to potential new treatment for allergy-induced asthma

...lved in asthmatic inflammation. The new study tracks the role of the ion channel protein TRPA1. While the exact function of TRPA1 in the airway inflammation...pletely understood, scientists do know from previous research that this ion channel protein is a sensor for chemical irritants such as cigarette smoke and cert...

Using high-precision laser tweezers to juggle cells

...method, where a set of laser tweezers move the cell around in a microscopic channel system, allows the researchers to study how single cells react to stress in... Placing the cell in a system of channels made of silicone, in which each channel is finer than a human hair, enables the researchers to add and remove subst...

NEWSLETTER: Antibody Fragment Production Breakthrough with 2nd Generation EBA

...age of higher density adsorbents and the proprietary design of an operational system which provides increased flow rates and is free from clogging and channel formation. Rhobust® has improved Richter-Helm’s offering to customers operating with microbial derived products, providing a superior down...

Striata and CIC Launch Integrated eSignature, eDelivery, and eBilling for the Financial Services Industry

...chose CIC's products to meet their needs. CIC has deployments with over 400 channel partners and enterprises worldwide representing hundreds of thousands of us...of paper. CIC sells directly to enterprises and through system integrators, channel partners and OEMs. CIC is headquartered in Redwood Shores, California and h...

Study reveals conflict between doctors, midwives over homebirth

...on Cheyney's research, and another that would ask physicians to recognize midwives as legitimate caregivers. Qualtere-Burcher said creating an open channel of communication isn't easy. "I do get some pushback from physician friends who say that I'm too open and too supportive," he said. "My answer, to ...

Meet DNA's personal assistants

...side the genetic pathway, where DNA produces proteins to sustain life, they found microRNA. These tiny ubiquitous molecules have opened a new research channel in biology, allowing scientists to more closely examine what causes genetic diseases, and what makes our cells tick. "This is a pivotal mechanism f...

Flow of potassium into cells implicated in schizophrenia

...treatments. Expression of a previously unknown form of a key such potassium channel was found to be 2.5 fold higher than normal in the brain memory hub of peop...ctly healthy people who carry the risk-associated version of this potassium channel gene, even though they don't show any psychotic behavior." Evidence sugg...

Drug prevents seizure progression in model of epilepsy

... is associated with seizure disorders, a potassium channel known as the BK channel. "We have found a new ...hemselves could lead to the same alterations in BK channel function. Potassium ions move through the channel...n researchers found that after a first seizure, BK channel function was markedly enhanced. As a result, the n...

Uncooperative voltage sensors

...d conformation at a depolarized voltage before the channel can open. Part of the evidence for this assertion ... gate from opening (Horn et al., 2000). Therefore, channel opening requires the participation of all four vol...vidence, that if three of the voltage sensors in a channel are in a permanently activated conformation, the f...

Laughing hyenas, wailing levees, the sound of cheese and blaring bagpipes

... and Greenland. In the 1800s they were heavily hunted in this area and haven't been seen much there since. Recently acoustic sensors stationed in this channel have discovered a return of right whales to their old territory. According to David Mellinger at the Oregon State University, the right whales were lo...

BIO-key(R) International Showcasing Biometric Identification Technology at 2009 RSA Conference

... any of the major manufacturers. BIO-key will feature their newest release of WEB-key(R), with Citrix Platform support across a single virtual channel interface. This unique solution can be easily deployed into any application to positively identify users before allowing access to valuable corporate ...

Researchers discover that gene switches on during development of epilepsy

...sition, to the condition. The gene codes a calcium channel in the brain that underlies seizures, so the findi...gh the brain. If, as in epilepsy, a particular channel shows up where it is not supposed to or appears in too many or too few numbers, the function that channel is responsible for can become abnormal. Researcher...

Translating the conversation between the brain and blood vessels

...y a role in the signaling between the brain and the blood vessels. In experiments with animals, Dr. Abboud and his colleagues deleted one specific ion channel and found that the animals developed high blood pressure. Work is now planned to develop a blood test to identify patients who suffer high blood press...

truTV and Cox Offer Free Digital Fingerprinting to Help Prevent Crimes Against Children

...incipals' Office, Forensic Files , Surf and Rescue, Speeders, Most Shocking, and The Smoking Gun Presents: World's Dumbest. During the daytime, the channel features expert trial coverage under the name IN SESSION. About Cox Communications Cox Communications is a multi-service broadband communic...

K-State using Second Life island to help high school students learn earth science

...ls. They can click on different organisms and bring up more information about them. They can watch videos from the Chicago Field Museum, the Discovery channel or National Geographic." Totten and Davies are working with Stacey Fox, a visiting assistant professor of art at the University of Kansas. Initial ...

Towards a natural pacemaker

... the new developments "will facilitate the development of practical biological pacemakers by allowing more complete and rapid assessment of individual channel mutations through combined culture and simulation studies prior to full testing in animal models." ...

Spring fishing season arrives... and with it, amphibian diseases

...d, these larvae of tiger salamanders used as live bait for freshwater fishing. With tiger salamander larvae, anglers hope to catch largemouth bass, channel catfish and other freshwater fishes. They may be in for more than they bargained for: salamanders in bait shops in Arizona, Colorado and New Mexico...

First tri-continuous mesoporous Silica complex structure developed in Singapore

...mportance for various chemical and biological applications. "IBN-9 demonstrates that it is possible to create three interwoven but independent pore channel systems along with a unique nano-fiber morphology," said Jackie Y. Ying, Ph.D., who led this research. "Such a mesostructure makes distinct diffus...

truTV and Cox Offer Free Digital Fingerprinting to Help Prevent Crimes Against Children

...incipals' Office, Forensic Files , Surf and Rescue, Speeders, Most Shocking, and The Smoking Gun Presents: World's Dumbest. During the daytime, the channel features expert trial coverage under the name IN SESSION. About Cox Communications Cox Communications is a multi-service broadband communic...

Targeted drug therapy prevents exercise-induced arrhythmias

...n cardiac deaths in young athletes. Current treatment has been limited to two medications beta blockers, often used at very high doses, and calcium channel blockers to control the arrhythmias. Implantable cardioverter defibrillators (ICDs) are placed in patients at high risk for sudden death, but ongoin...

UniPixel Announces Availability of Opcuity(TM) Finger Print Resistant Film Test Samples

...t production samples that can be applied to touch screen enabled hand held devices. UniPixel is making these samples available to marketing and sales channel partners for test and evaluation prior to market entry. Interested parties can contact UniPixel directly to register as a partner and receive samples...

Journal of General Physiology explores mysteries of TRP channels in latest Perspectives series

... a critical overview of current research about TRP channel structure, and to point out areas in need of furth...araiso) provides an historical context for the TRP channel story, which dates back to the 1960s and now inclu...dulation of the functional properties of the TRPA1 channel and, in particular, that regarding its temperature...
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