Breast in Biological News

The way you eat may affect your risk for breast cancer

PHILADELPHIA How you eat may be just as important as how much you eat, if mice studies are any clue. Cancer researchers have long studied the role of diet on breast cancer risk, but results to date have been mixed. New findings published in Cancer Prevention Research , a journal of the Ameri...

Stem cell 'daughters' lead to breast cancer

Walter and Eliza Hall Institute scientists have found that a population of breast cells called luminal progenitor cells are likely to be responsible for breast cancers that develop in women carrying mutations in the gene BRCA1. BRCA1 gene mutations are found in 10-20 per cent of women with hered...

Possible drug target found for one of the most aggressive breast cancers

Grand Rapids, Mich. (July 8, 2009) Van Andel Research Institute (VARI) investigators have identified a gene that could be an important therapeutic target in the treatment of the most aggressive forms of breast cancer. Currently, patients with these cancers have few treatment options. "Breast...

New MRI technique could mean fewer breast biopsies in high-risk women

MADISON A University of Wisconsin-Madison biomedical engineer and colleagues have developed a method that, applied in MRI scans of the breast, could spare some women with increased breast cancer risk the pain and stress of having to endure a biopsy of a questionable lump or lesion. The univers...

Protein linked to change in tissue that surround and support breast tumors

Washington, DC A protein known to be overly active in breast cancer can exist in a form that seems to change the structural composition of mammary tissue, potentially making it more conducive to tumor progression, say researchers from the Lombardi Comprehensive Cancer Center at Georgetown Univers...

Dual role in breast tissue for a protein involved in leukemia

Washington, DC - A protein known to play a role in growth of some types of leukemia appears to have a mixed function in breast cancer development, say researchers from the Lombardi Comprehensive Cancer Center at Georgetown University Medical Center (GUMC). The findings, presented at the annual ...

Wet ear wax and unpleasant body odors signal breast cancer risk

If having malodorous armpits (called osmidrosis) and goopy earwax isn't bad enough, a discovery by Japanese scientists may add a more serious problem for women facing these cosmetic calamities. That's because they've found that a gene responsible for breast cancer causes these physical symptoms. T...

Lombardi scientist brings 'dream team' breast cancer research effort to GUMC

Washington, DC -- It's called a "Dream Team." Lombardi Comprehensive Cancer Center's incoming scientific director V. Craig Jordan, OBE, PhD, DSc, and 12 of the nation's top breast cancer researchers have been awarded a multi-million dollar grant from Stand Up To Cancer (SU2C) to form a scientif...

Genetic testing for breast or ovarian cancer risk may be greatly underutilized

Although a test for gene mutations known to significantly increase the risk of hereditary breast or ovarian cancer has been available for more than a decade, a new study finds that few women with family histories of these cancers are even discussing genetic testing with their physicians or other h...

UNC study identifies genetic cause of most common form of breast cancer

The discovery of tumor-suppressor genes has been key to unlocking the molecular and cellular mechanisms leading to uncontrolled cell proliferation the hallmark of cancer. Often, these genes will work in concert with others in a complex biochemical system that keeps our cells growing and dividing...

IMPAKT -- Breast cancer conference highlights

If you are interested in receiving the full text of the press releases and the related abstracts, please contact media@esmo.org Please note that all news releases are embargoed until Thursday, 7 May 2009, 14:00 (CEST) GENE SIGNATURE IDENTIFIES BREAST CANCER PATIENTS WHO WILL RESPOND TO CHE...

UC Davis researchers identify a protein that may help breast cancer spread, beat cancer drugs

(SACRAMENTO, Calif.) New research from UC Davis Cancer Center shows that a protein called Muc4 may be the essential ingredient that allows breast cancer to spread to other organs and resist therapeutic treatment. The study, which appears in the April 1 issue of Cancer Research , is one of the fi...

Twin nanoparticle shown effective at targeting, killing breast cancer cells

PROVIDENCE, R.I. [Brown University] Breast cancer patients face many horrors, including those that arise when fighting the cancer itself. Medications given during chemotherapy can have wicked side effects, including vomiting, dizziness, anemia and hair loss. These side effects occur because medic...

Safeway gives $685,000 to TGen for breast cancer research

PHOENIX, Ariz. March 4, 2009 Despite a down economy, Safeway Inc. presented a $685,236 check this week for breast cancer research at the Translational Genomics Research Institute (TGen). Dan Valenzuela, President of Safeway's Phoenix Division, which includes 116 stores throughout Arizona, tha...

New test for breast cancer will help guide treatment choices

SALT LAKE CITY One in eight women in the United States will receive a diagnosis of breast cancer in their lifetime, and it is the second leading cause of cancer-related death in women. Now a new test will help physicians determine the best possible treatment for each patient. "Our research sh...

Statin therapy ineffective in breast cancer prevention

PHILADELPHIA Laboratory work in animals showed limited activity when statins were given to prevent breast cancer, according to a report in the February issue of Cancer Prevention Research , a journal of the American Association for Cancer Research. Statins, sold under brand names like Lipito...

Hispanic women and breast cancer: An understudied group

This release is available in Spanish . CAREFREE, A.Z. - Data from the ELLA Binational Breast Cancer Study will be released for the first time at the American Association for Cancer Research Conference on the Science of Cancer Health Disparities in Carefree, Arizona. "Hispanics are the ...

Stroma genomic signature predicts resistance to anthracyclin-based chemotherapy in breast cancer

Researchers at the Swiss Institute of Bioinformatics and the Swiss National Center of Competence in Research in Molecular Oncology in Lausanne have developed a new test to predict how breast cancer patients respond to chemotherapy, which could help change how treatment is delivered in the future. ...

New technique images tumor vessel leakiness to predict breast cancer chemotherapy outcome

Chemotherapy is an integral part of modern cancer treatment, but it's not always effective. Successful chemotherapy depends on the ability of anticancer drugs to escape from the bloodstream through the leaky blood vessels that often surround tumors. Predicting chemotherapy's efficacy could save...

HWI scientist first in world to unravel structure of key breast cancer target enzyme

The molecular details of Aromatase, the key enzyme required for the body to make estrogen, are no longer a mystery thanks to the structural biology work done by the Ghosh lab at the Hauptman-Woodward Medical Research Institute (HWI) in Buffalo, New York. Dr. Debashis Ghosh's solution of the three...

Team finds breast cancer gene linked to disease spread

A team of researchers at Princeton University and The Cancer Institute of New Jersey has identified a long-sought gene that is fatefully switched on in 30 to 40 percent of all breast cancer patients, spreading the disease, resisting traditional chemotherapies and eventually leading to death. Th...

Ireland Cancer Center researcher finds most triple-negative breast cancers express muc-1 target

CLEVELAND: Research out of the Ireland Cancer Center of University Hospitals Case Medical Center has found that the vast majority of triple negative breast cancers express the MUC-1 target. This first-of-its-kind finding, presented today at the San Antonio Breast Cancer Symposium, has paved the w...

Easton honored with inaugural AACR Outstanding Investigator Award in Breast Cancer Research

SAN ANTONIO Douglas Easton, Ph.D., whose international studies in breast cancer explained the genetic patterns and causes of the BRCA1 and BRCA2 gene mutations which indicate a person's risk for breast cancer, has been selected to receive the inaugural American Association for Cancer Research (AA...

Massague honored with inaugural AACR Distinguished Leadership Award in Breast Cancer Research

SAN ANTONIO Joan Massagu, Ph.D., whose research identified the role of transforming growth hormone factor-Beta (TGF-Beta) in the metastasis of breast cancer cells to the lung, has been selected to receive the inaugural AACR Distinguished Leadership Award in Breast Cancer Research. Massagu spen...

Eating eggs when pregnant affects breast cancer in offspring

A stunning discovery based on epigenetics (the inheritance of propensities acquired in the womb) reveals that consuming cholinea nutrient found in eggs and other foodsduring pregnancy may significantly affect breast cancer outcomes for a mother's offspring. This finding by a team of biologists at ...

European ancestry increases breast cancer risk among Latinas

PHILADELPHIA Latina women have a lower risk of breast cancer than European or African-American women generally, but those with higher European ancestry could be at increased risk, according to data published in the December 1 issue of Cancer Research , a journal of the American Association for C...

2 new compounds show promise for eliminating breast cancer tumors

Two new compounds created by a University of Central Florida professor show early promise for destroying breast cancer tumors. Associate Professor James Turkson's compounds disrupt the formation and spread of breast cancer tumors in tests on mice. The compounds, S3I-201 and S3I-M2001, break up...

Two new compounds show promise for eliminating breast cancer tumors

Two new compounds created by a University of Central Florida professor show early promise for destroying breast cancer tumors. Associate Professor James Turkson's compounds disrupt the formation and spread of breast cancer tumors in tests on mice. The compounds, S3I-201 and S3I-M2001, break up...

Mayo researchers identify dangerous 'two-faced' protein crucial to breast cancer spread and growth

JACKSONVILLE, Fla. Two critical properties of cancer cells are their ability to divide without restraint and to spread away from the primary tumor to establish new tumor sites. Now, researchers from the Mayo Clinic campus in Florida have found a protein they say acts as a deadly master switch, b...

Einstein researchers develop a new way to study how breast cancer spreads

November 09, 2008─Bronx, NY─ In a breakthrough study appearing in advance online publication of Nature Methods , researchers at Albert Einstein College of Medicine of Yeshiva University describe for the first time a method of viewing individual breast cancer cells for several days at ...

CTRC-AACR San Antonio Breast Cancer Symposium

The CTRC-AACR San Antonio Breast Cancer Symposium features the latest findings in laboratory, translational and clinical breast cancer research. This year's meeting focuses on new and promising therapeutic approaches, as well as strides being made in diagnosing and preventing breast cancer. To ...

UC Davis researchers discover a key to aggressive breast cancer

(SACRAMENTO, Calif.) In trying to find out why HER2-positive breast cancer can be more aggressive than other forms of the disease, UC Davis Cancer Center researchers have surprisingly discovered that HER2 itself is the culprit. By shutting down its own regulator gene, HER2 creates a permissive en...

Study links nicotine with breast cancer growth and spread

PHILADELPHIA A study published in Cancer Research , a journal of the American Association for Cancer Research, suggests a possible role for nicotine in breast tumor development and metastases. The study, conducted by researchers at the Beth Israel Deaconess Medical Center, is among the first...

SNM releases new fact sheet on breast cancer and molecular imaging

RESTON, Va.Coinciding with the observance of Nuclear Medicine Week (October 5 to 11) and National Breast Cancer Awareness Month (October), SNM released today a new fact sheet highlighting recent developments in molecular imaging technologies that are dramatically improving the ways in which breast...

Study looks at psychological impact of gene test for breast cancer

Personal beliefs about inconclusive DNA testing for hereditary breast cancer are associated with cancer-related worry, and such beliefs are an especially strong predictor of whether women had been able to leave the period of DNA-testing behind, reports a study in the October issue of Genetics in ...

Second lumpectomy for breast cancer reduces survival rates

(SACRAMENTO, Calif.) A majority of women with breast cancer today are candidates for lumpectomy, allowing for conservation of most of their breast tissue. Results of a UC Davis study, however, show that a number of women whose cancer recurs in the same breast are treated with a second lumpectomy ...

The dietary supplement genistein can undermine breast cancer treatment

CHAMPAIGN, Ill. Women taking aromatase inhibitors to treat breast cancer or prevent its recurrence should think twice before also taking a soy-based dietary supplement, researchers report. Genistein, a soy isoflavone that mimics the effects of estrogen in the body, can negate the effectiveness...

Expanding cell girth indicates seriousness of breast cancer

WEST LAFAYETTE, Ind. - How fat cells become after being exposed to a specialized electrical field is helping researchers determine whether cells are normal, cancerous or a stage of cancer already invading other parts of the body. Purdue University scientists tested the electrical process and fo...

Stem cells may solve mystery of early pregnancy breast cancer protection

The answer to why an early pregnancy seems to protect against breast cancer could rest with a decrease in stem cells found after animals have given birth, said researchers at Baylor College of Medicine in a report that appears in the current issue of the journal Stem Cell. Women who have chil...

Vaccine against HER2-positive breast cancer offers complete protection in lab

PHILADELPHIA Researchers at Wayne State University have tested a breast cancer vaccine they say completely eliminated HER2-positive tumors in mice - even cancers resistant to current anti-HER2 therapy - without any toxicity. The study, reported in the September 15 issue of Cancer Research, a...