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Bone in Biological News

Scientists closer to making implantable bone material, thanks to new research

Scientists are closer to understanding how to grow replacement bones with stem cell technology, thanks to research published today in the journal Nature Materials . Many scientists are currently trying to create bone-like materials, derived from stem cells, to implant into patients who have d...

UAB study reveals bone coupling factor key to skeletal health

BIRMINGHAM, Ala. Researchers at the University of Alabama at Birmingham (UAB) have discovered a molecular coupling factor that helps bones grow and remodel themselves to stay strong, a finding that could lead to better bone-building therapies and new osteoporosis drugs, the researchers said Th...

Fossil bone bed helps reconstruct life along California's ancient coastline

Berkeley In the famed Sharktooth Hill Bone Bed near Bakersfield, Calif., shark teeth as big as a hand and weighing a pound each, intermixed with copious bones from extinct seals and whales, seem to tell of a 15-million-year-old killing ground. Yet, new research by a team of paleontologists fro...

Adult bone marrow stem cells injected into skeletal muscle can repair heart tissue

BUFFALO, N.Y. -- University at Buffalo researchers have demonstrated for the first time that injecting adult bone marrow stem cells into skeletal muscle can repair cardiac tissue, reversing heart failure. Using an animal model, the researchers showed that this non-invasive procedure increased...

Study finds link between hot flashes and lower bone density in women

FINDINGS: UCLA researchers and colleagues analyzed data for 2,213 women between the ages of 42 and 52 who participated in the bone sub-study of the Study of Women's Health Across the Nation to determine whether women with vasomotor symptoms (VMS) which include hot flashes and night sweats had l...

Multiple route bone marrow stem cell injections show promise to treat spinal cord injury

Tampa, Fla. (Mar. 12, 2009) Researchers from DaVinci Biosciences, Costa Mesa, California, in collaboration with Hospital Luis Vernaza in Ecuador, have determined that injecting a patient's own bone marrow-derived stem cells (autologous BMCs) directly into the spinal column using multiple routes c...

Metastatic bone disease patients can walk in Lazarus' footsteps

SAN DIEGO, Calif. (March 9, 2009)Osteoplastya highly effective minimally invasive procedure to treat the painful effects of metastatic bone disease by injecting bone cement to support weakened bonesprovides immediate and substantial pain relief, often presenting individuals who are suffering terri...

Moderate alcohol intake associated with bone protection

BOSTON - (March 3, 2009) In an epidemiological study of men and post-menopausal women primarily over 60 years of age, regular moderate alcohol intake was associated with greater bone mineral density (BMD). Researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at ...

Biomedical researchers create artificial human bone marrow in a test tube

ANN ARBOR, Mich.--- Artificial bone marrow that can continuously make red and white blood cells has been created in a University of Michigan lab. This development could lead to simpler pharmaceutical drug testing, closer study of immune system defects and a continuous supply of blood for trans...

Columbia University scientist devises new way to more rapidly generate bone tissue

NEW YORK (Dec. 15, 2008) Using stem cell lines not typically combined, researchers at Columbia University Medical Center have designed a new way to "grow" bone and other tissues. The inability to foster angiogenesis a physiological process involving the growth of new blood vessels from pre-ex...

Stowers Institute's Linheng Li Lab expands understanding of bone marrow stem cell niche

The Stowers Institute's Linheng Li Lab has identified the precise location of the bone marrow stem cell niche. The findings were published today in the Advance Online Publication of Nature . The Linheng Li Lab collaborated with several of the Institute's support facilities to develop a new te...

Calcium and vitamin D may not be the only protection against bone loss

Chevy Chase, MDDiets that are high in protein and cereal grains produce an excess of acid in the body which may increase calcium excretion and weaken bones, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism ( JCEM ). The s...

Adiponectin is a metabolic link between obesity and bone mineral density

Researchers at the University of Toronto, Faculty of Medicine, Toronto, Canada, have discovered that adiponectin, a protein secreted from adipocytes, is a metabolic link that can explain, in part, the known positive relationship between obesity and both bone mineral density and reduced susceptibil...

Nutrition and bone health session to open the IOF World Congress on Osteoporosis in Bangkok

The IOF World Congress on Osteoporosis, the largest scientific conference devoted primarily to osteoporosis, will open on December 3rd in Bangkok with a special session focused on four key topics in nutrition and bone health. Professor Cyrus Cooper, Director of the MRC Epidemiology Resource Ce...

Scientists discover bacteria that can cause bone infections

Scientists have discovered that a bone infection is caused by a newly described species of bacteria that is related to the tuberculosis pathogen. The discovery may help improve the diagnosis and treatment of similar infections, according to an article published in the October issue of the Interna...

Sweat it out: UH study examines ability of sweat patches to monitor bone loss

Some health assessments that are routinely carried out on Earth are not practical when the "patients" are free-floating astronauts on long space flights, such as missions to Mars or the Moon. A new, NASA-funded study from the University of Houston department of health and human performance will e...

NC State first university in nation to offer canine bone marrow transplants

Dogs suffering from lymphoma will be able to receive the same type of medical treatment as their human counterparts, as North Carolina State University becomes the first university in the nation to offer canine bone marrow transplants in a clinical setting. Dr. Steven Suter, assistant professor...

Engineers create bone that blends into tendons

Engineers at Georgia Tech have used skin cells to create artificial bones that mimic the ability of natural bone to blend into other tissues such as tendons or ligaments. The artificial bones display a gradual change from bone to softer tissue rather than the sudden shift of previously developed a...

Hydrogels provide scaffolding for growth of bone cells

PHILADELPHIAHyaluronic hydrogels developed by Carnegie Mellon University researchers may provide a suitable scaffolding to enable bone regeneration. The hydrogels, created by Newell Washburn, Krzysztof Matyjaszewski and Jeffrey Hollinger, have proven to encourage the growth of preosteoblast cells,...

Childhood dairy intake may improve adolescent bone health

Cincinnati, OH, August 13, 2008Dairy is recognized as a key component of a healthy, balanced diet. However, until recently it was unclear how long-term dairy intake contributes to the many aspects of bone health in children, including bone density, bone mineral content, and bone area. A new stud...

Accelerated bone turnover remains after weight loss

COLUMBIA, Mo. When a person is losing a significant amount of weight, they expect to notice changes in their body. However, they may overlook changes happening in their bones. During weight loss through calorie-restricted diets, bones are being remodeled - breaking down old bone and forming new b...

Small protein may have big role in making more bone and less fat

A small protein may have a big role in helping you make more bone and less fat, researchers say. "The pathways are parallel, and the idea is if you can somehow disrupt the fat production pathway, you will get more bone," says Dr. Xingming Shi, bone biologist at the Medical College of Georgia In...

Prevent a bone break, drink milk to boost calcium

Boosting calcium intake by drinking milk could reduce healthy adults' chances of a debilitating bone break. In a new study published in the American Journal of Clinical Nutrition, healthy men and women supplemented with 1,200 mg of calcium per day the amount in four glasses of milk reduced their...

Genetic sequencing of protein from T. rex bone confirms dinosaurs' link to birds

Scientists have put more meat on the theory that dinosaurs' closest living relatives are modern-day birds. Molecular analysis, or genetic sequencing, of a 68-million-year-old Tyrannosaurus rex protein from the dinosaur's femur confirms that T. rex shares a common ancestry with chickens, ostrich...

A fossilized giant rhino bone questions the isolation of Anatolia, 25 million years ago

Contrary to generally accepted belief, Anatolia was not geographically isolated 25 million years ago (during the Oligocene epoch): this has just been demonstrated by researchers from the Laboratoire des Mcanismes et Transferts en Gologie (LMTG) (CNRS/ University of Toulouse 3/IRD) and the Palobiod...

Got carrots? Vegetables may have bone to pick as calcium providers

COLLEGE STATION A specially developed carrot has been produced to help people absorb more calcium. Researchers at Texas A&M AgriLifes Vegetable and Fruit Improvement Center studied the calcium intake of humans who ate the carrot and found a net increase in calcium absorption. The research, w...

New treatment boosts bone healing and regrowth

BIRMINGHAM, Ala. A drug originally used to treat iron poisoning can significantly boost the bodys own ability to heal and re-grow injured bones, according to researchers at the University of Alabama at Birmingham (UAB). The researchers injected the drug deferoxamine (DF), which is designed to ...

Researchers discover protein that controls bone growth

A research team led by Dr. Pierre Moffatt of the Shriners Hospital for Children in Montreal and McGill Universitys Department of Human Genetics has uncovered the molecular mechanism by which the protein osteocrin controls bone growth a discovery that may have important implications for people suf...

Human embryonic stem cell -- derived bone tissue closes massive skull injury

There are mice in Baltimore whose skulls were made whole again by bone tissue grown from human embryonic stem cells (hESCs). Healing critical-size defects (defects that would not otherwise heal on their own) in intramembraneous bone, the flat bone type that forms the skull, is a vivid demonstr...

Study suggests link between obesity, poor bone health

Athens, Ga. Being overweight is a known risk factor for heart disease, diabetes and a host of other health conditions. Now, a University of Georgia study published in the November issue of the American Journal of Clinical Nutrition finds that obesity may also be bad for bone health. Researcher...

Study shows some athletic men may risk low bone density

COLUMBIA, Mo. According to the National Osteoporosis Foundation, osteoporosis affects more than 2 million men in the United States and nearly 12 million more have osteopeniaclinically significant low bone density that is less severe than osteoporosis. Now, a new study from the University of Miss...

Paracetamol, one of most used analgesics, could slow down bone growth

In Medicine, paracetamol is used to soothe every kind of pain, from simple molar pain to pain produced by bone fractures. This medicine is one of the most used nowadays. However, research carried out at the Departamento de Enfermeria of the University of Granada showed that taking paracetamol ...

Layered approach may yield stronger, more successful bone implants

Researchers from the American Dental Association Foundation (ADAF) and the National Institute of Standards and Technology (NIST) have developed a new method for layering two kinds of biomaterials into one strong, yet porous unit that may lead to improved reconstruction or repair of bones. Curre...

MIT: New tissue scaffold regrows cartilage and bone

CAMBRIDGE, Mass.--MIT engineers and colleagues have built a new tissue scaffold that can stimulate bone and cartilage growth when transplanted into the knees and other joints. The scaffold could offer a potential new treatment for sports injuries and other cartilage damage, such as arthritis, s...

New research lights up chronic bacterial infection inside bone

December 22, 2008, Cambridge, UK A new report demonstrates how a sensitive imaging technique gives scientists the upper hand in seeking out bacteria in chronic infections. Listeria monocytogenes is a type of pathogenic bacteria that can cause severe illness and death. Listeria outbreaks rece...

Dietary calcium could possibly prevent the spread of breast cancer to bone

PHILADELPHIA A strong skeleton is less likely to be penetrated by metastasizing cancer cells, so a fortified glass of milk might be the way to block cancers spread, according to researchers at the ANZAC Research Institute in Concord, Australia. Using a mouse model of breast cancer metastasis, the...

Research shows cord blood comparable to matched bone marrow

University of Minnesota researchers report that umbilical cord blood transplants may offer blood cancer patients better outcomes than bone marrow transplants, according to an analysis of outcome data performed at the Center for International Blood and Marrow Transplant Research (CIBMTR), Medical C...

Molecule that destroys bone also protects it, new research shows

An immune system component that is a primary cause of bone destruction and inflammation in autoimmune diseases such as rheumatoid arthritis actually protects bone in the oral cavity from infectious pathogens that play a major role in periodontal disease in humans, research at the University at Buff...

Intelligent materials to regenerate bone tissue

More than half a million people in the European Union and a million in the United States suffer from disorders in or serious defects of some part of their bone structure. Operations involving grafts or implants, required to mitigate the damage, depend decisively on the materials used. The Europea...

NIH researchers discover protein that appears to regulate bone mass loss, the cause of osteoporosis

An estimated ten million Americans suffer from osteoporosis, and another 34 million Americans are at risk of developing the disease, which is characterized by a severe loss of bone mineral density, fragile bones and an increased risk of hip, spine and wrist fractures. The basic mechanism behind ost...
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