Biomarkers in Biological News

Prostate Cancer Translational Research in Europe meeting: Search for biomarkers continues

Amsterdam, 22 June 2009 - Collaboration in prostate cancer translational research in Europe is not only vital to sustain the progress achieved in recent years but also to streamline current efforts between researchers and clinicians and avoid duplication or overlaps. This was amongst the goals of ...

Compendium of pancreatic cancer biomarkers established as strategic approach to early-detection

A cancer scientist from Johns Hopkins has convinced an international group of colleagues to delay their race to find new cancer biomarkers and instead begin a 7,000-hour slog through a compendium of 50,000 scientific articles already published to assemble, decode and analyze the molecules that mig...

Urologists identify 7 biomarkers that may help pinpoint prostate cancer recurrence

DALLAS June 15, 2008 A simple blood test may help doctors better predict whether prostate cancer will recur or spread in patients who have undergone surgery for the disease, researchers at UT Southwestern Medical Center have found. In a study published in the June 15 issue of Clinical Cancer...

Scientists find potential protein biomarkers for growth hormone

SAN FRANCISCO Ohio University scientists have identified several proteins in mice that might act as biomarkers for growth hormone. The research could be the first step to finding a more reliable way to detect recombinant human growth hormone (rhGH), which some athletes and teenagers use illegally...

A search for biomarkers for early detection of colorectal cancer

Researchers at the Zhejiang University, Hangzhou have discovered that mimecan and Thioredoxin Domain-Containing Protein 5 (TXNDC5) were differentially expressed in colorectal adenoma. The research article describing this work entitled Differential Expression of Mimecan and Thioredoxin Domain-Conta...

Genetic Engineering & Biotechnology News reports on cancer biomarkers

New Rochelle, NY, April 1, 2008Biotechnology companies are focusing on the development of novel biomarkers to overcome the limitations of current diagnostic tests for cancer, reports Genetic Engineering and Biotechnology News (GEN). To effectively move cancer therapy forward, a much stronger and t...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

Genetic and epigenetic variations ensure that no two people are exactly alike, and the same holds true for any two cancers. Now, researchers have the tools and the knowledge to help predict how individuals will respond to cancer therapies, enabling them to create more effective therapies for indiv...

NIH stimulus funding supports Emory biomedical scientists

...teins can improve treatments for inherited hemophilia and cardiovascular disease. This study looks at one particular clotting protein, factor VIII. biomarkers for Alzheimer's via magnetic resonance: Identifying patients who are developing Alzheimer's disease could help neurologists treat it earlier and poss...

Moving to the US increases cancer risk for Hispanics

...earcher. Pinheiro received support from the Portuguese Foundation for Science and Technology. These results are published in Cancer Epidemiology, biomarkers & Prevention , a journal of the American Association for Cancer Research. Studies to date have classified all Hispanics under the same umbrella, a...

More than half of Texas physicians do not always recommend HPV vaccine to girls

...hese recommendations. The survey was published in Cancer Epidemiology, biomarkers & Prevention , a journal of the American Association for Cancer Research. ... said Vernon, who is also an editorial board member of Cancer Epidemiology, biomarkers & Prevention. ...

Women often opt to surgically remove their breasts, ovaries to reduce cancer risk

...varian cancer are choosing to undergo surgery as a precautionary measure to decrease their cancer risk, according to a report in Cancer Epidemiology, biomarkers & Prevention , a journal of the American Association for Cancer Research. "Women have their breasts or ovaries removed based on their risk. It does...

The way you eat may affect your risk for breast cancer

...gain lost weight discouraging the application of calorie restriction protocols for disease prevention," she said. "We hope these studies will identify biomarkers and/or pathways that could be used in human studies to determine agents that would mimic calorie restriction." ...

Cancer's distinctive pattern of gene expression could aid early screening and prevention

...tectable in the plasma samples of lymphoma patients, making it a good candidate for the screening, says Dr. Shi who also is looking for these types of biomarkers in breast cancer and the aggressive adult brain tumor glioblastoma. Dr. Robertson, who also works in breast cancer and brain tumors as well as colo...

$2 million grant aids study of lung cancer in people who never smoked

...DALLAS July 21, 2009 Researchers at UT Southwestern Medical Center are among an elite group of cancer scientists to share a $2 million grant to find biomarkers for lung cancer that develops in people who have never smoked. The National Cancer Institute's Early Detection Research Network (EDRN) and the Cana...

Results from trials of DHA in Alzheimer's disease and age-related cognitive decline

...er to test therapies at earlier stages of the disease and enable earlier intervention." Other research studies from ICAD 2009 show advances made in biomarkers and early detection from the Alzheimer's Disease Neuroimaging Initiative (ADNI), and also survey results from doctors about the enablers and barriers ...

22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey

...or treatment News on the NewMood project The educational update sessions at the ECNP Congress will deal with the current knowledge on GABA and biomarkers in neuropsychopharmacology, treatment of insomnia, bipolar disorders and schizophrenia, as well as the new classification systems ICD-11 and DSM-V. ...

2 reproductive factors are important predictors of death from ovarian cancer

...cer diagnosis. Results of this study are published in Cancer Epidemiology, biomarkers & Prevention , a journal of the American Association for Cancer Research. ... said Daly, who is also an editorial board member for Cancer Epidemiology, biomarkers & Prevention . "The next steps would be to study this association in a pros...

Will IVF work for a particular patient? The answer may be found in her blood

...he results generated by this work will lead to the development of a test to aid in IVF decision-making. They say that their work will help to identity biomarkers that can identify events occurring at implantation, the maintenance of pregnancy and successful or unsuccessful pregnancy outcome. "IVF technolog...

New biomarker method could increase the number of diagnostic tests for cancer

...a new method for detecting and quantifying protein biomarkers in body fluids may ultimately make it possible to screen multiple biomarkers in hundreds of patient samples, thus ensuring that...thod to increase accuracy in detecting real cancer biomarkers that is highly reproducible across laboratories an...

A urine test for appendicitis?

...citis already have a ruptured appendix. Laboratory biomarkers have been identified, but none have proved reliabl...of the test performance. Seven promising urine biomarkers were identified. The best of them was leucine-rich...tudy was limited to children, and that patterns of biomarkers likely vary in older patients, LRG testing would n...

Green tea may affect prostate cancer progression

...ntation with green tea's active compounds on serum biomarkers in patients with prostate cancer. The biomarkers include hepatocyte growth factor (HGF), vascular e...hers. Cardelli and colleagues found that other biomarkers were also positively affected. There were only a f...

Research uncovers clues to virus-cancer link

...trolled cell growth. Dittmer's team examined samples of tissue provided with the consent of Kaposi's sarcoma patients and found that specific miRNA biomarkers accurately identify stages of tumor progression. They found that certain miRNAs were lost as the tumors progressed, effectively accelerating the canc...

Test detects molecular marker of aging in humans

...ncreased exponentially with age. In addition, increased levels were independently associated with tobacco use and physical inactivity as well as with biomarkers of human frailty. Sharpless said that the researchers were surprised by some of their findings, "We found a very weak correlation between the bioma...

Study finds colorectal cancer rates increasing worldwide

...r-reviewed journal to present colorectal cancer incidence trends across all five continents. It appears in the June 2009 issue of Cancer Epidemiology biomarkers and Prevention . An accompanying editorial says the rise points toward a failed early detection and prevention strategy as well as failure to address ...

Gene activity reveals dynamic stroma microenvironment in prostate cancer

...land, only 5 percent would die from the disease. How do we differentiate those who really need treatment from those who might not? Can we identify the biomarkers that differentiate those? There is probably more than one marker and some may be stromal-based." ...

University of Saskatchewan and Canadian Synchrotron researchers shed light on esophageal disease

...on light is that it allows us to identify chemical biomarkers inside specific cells," says Dr. Quaroni, who cond...and Casson identified specific chemicals known as biomarkers - within the individual cells that make up the tis... found that increased concentrations of particular biomarkers such as glycoproteins were associated with the Bar...

International Serious Adverse Events Consortium announces initial study results in its global research collaboration to identify genetic markers related to drug induced liver injury

...tial results to the research community, to both improve the productivity of drug development and to begin the critical process of developing validated biomarkers to forecast patients who may be at risk for DILI," said Arthur Holden, founder and chairman of the SAEC. "To date, in conjunction with our collaborato...

22nd Congress of the European College of Neuropsychopharmacology

...atment News on the NewMood project Furthermore, the educational update sessions at the congress will deal with the current knowledge on GABA and biomarkers in neuropsychopharmacology, treatment of insomnia, bipolar disorders and schizophrenia, and the new classification systems ICD-11 and DSM-V. ...

Tips from the American Journal of Pathology

...genes, and found that a subset of these candidates were associated with disease progression and glomerular filtration rate in human patients. The biomarkers identified by Dr. Bttinger, Dr. Kretzler, and colleagues "predict progressive renal fibrosis in mice and may [therefore] be useful molecular predictor...

Stanford scientists find heat-tolerant coral reefs that may resist climate change

...forts in coral conservation." The ultimate goal is to find protein biomarkers that indicate signs of heat stress and potential heat resistance, Oliver ex...uld go to a reef, take small coral samples and test for the presence of the biomarkers to see how resilient the reef will be to higher temperatures. "Wi...

Are you okay to kiss?

...Checking the sweetness of one's breath may seem frivolous, but millions worry about it on a continual basis. Prof. Rosenberg's continued research into biomarkers in saliva is very promising for diagnosing other more serious disorders, including indicators for lung cancer, asthma and ulcers. Prof. Rosenberg h...

GenWay Biotech obtains exclusive rights to AMDL's DR-70 cancer test in US and Canada

...tal, ovarian, esophageal, cervical, trophoblastic, thyroid, malignant lymphoma, brain and pancreatic cancer making it one of the most versatile cancer biomarkers available. The GenWay team is looking forward to the future impact of the DR-70 test in the field of cancer diagnostics. Robert Gans, CEO of GenWa...

ACLU -- Myriad Genetics lawsuit will become landmark case

...iminished and innovation is smothered." Kenneth I. Berns, M.D., Ph.D., Editor in Chief of the peer reviewed journal, Genetic Testing and Molecular biomarkers ( http://www.liebertpub.com/gtmb ), which is the official journal of the Genetic Alliance, says the "patenting of human genes is a bad idea and that ...

Researchers gain genome-wide insights into patterns of the world's human population structures

...nces, matching each of the most informative axes of variation. These variations represent numerous fixed positions on the human genome where different biomarkers can sit and thereby form a "genomic signature" of population structure. They also allow for more detailed inferences, the UW researchers noted, about ...

SNM's clinical trials network gains added support from industry leader

... drug discovery through the integration of imaging biomarkers into multi-center clinical trials, recently added ...ugh the integration and standardization of imaging biomarkers into Phase 1, 2, 3 and 4 therapeutic clinical tria...o address critical needs for incorporating imaging biomarkers into multi-center trials. A formal introduction to...

New early detection studies of lung cancer in non-smokers launched today

... Government and private sector cancer scientists today launched a research partnership to find biomarkers for lung cancer that develops in people who have never smoked. The research studies are designed to create a better understanding of the biology of lu...

Personalized treatment for early lung cancer

...from the treatment. "Because the benefits of vaccination will be limited to a subgroup of patients, strategies to define these patients by means of biomarkers such as a genetic signature are of major clinical relevance, as only these patients might be candidates for vaccination in the future." A larger, phas...

Study validates means to measure possible leukemia marker

...od for reliably measuring variations in certain proteins that may make good biomarkers in chronic leukemia patients. The study shows that liquid chromatography-... that we have validated the technique, we can apply it to study histones as biomarkers that clinicians can use to make decisions about diagnosis and treatment," s...

Older men more likely than women to die after pneumonia

...s indicators including D-dimer concentrations. They found patterns in these biomarkers that suggest men generate a stronger inflammatory and coagulation response ...infection. "These differences in inflammatory, coagulation and fibrinolysis biomarkers among men may explain the reduced short-term and long-term survival," said ...

Newly discovered epidermal growth factor receptor active in human pancreatic cancers

...t for a large subset of pancreatic cancers and a potential blood or urine screening tool that might eventually do for pancreatic cancer detection what biomarkers like prostate-specific antigen levels have done for prostate cancer. His presentation was part of the scientific program of the American Society for I...