BioChemi

BRCA1 causes ovarian cancer through indirect, biochemical route

Mutated BRCA1 genes cause ovarian cancer indirectly, by interfering with the biochemical signals one ovarian cell sends to another, according to a team of researchers led by scientists at the USC/Norris Comprehensive Cancer Center and the Keck School of Medicine of the University of Southern California. Their work is being published in the March 29 issue of the journal Current Biology.</p...

MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks

Dr. Roger Brent, President and Director of Research at the the release of a new approach to simulation of intracellularbiochemical networks in the January 2005 edition of NatureBiotechnology.The research article, entit...

Biochemists report discovery of structure of major piece of telomerase; implications for cancer

UCLA biochemists have determined the three-dimensional structure of a major domain of telomerase, the enzyme that helps maintain telomeres ?small pieces of DNA on the ends of chromosomes that act as protective caps -- allowing DNA ends to be copied completely when cells are replicated. This is the first major piece of telomerase for which the structure is known. Telomerase plays a key rol...

Digging in the dirt for life's biochemical foundations

It seems a mighty feat for a microscopic fungus built from threadlike filaments. But collectively, these spindly mushroom relatives help move several billion tons of nutrients out of the soil and into plants each year. Now, new Michigan State University-supported research on the movement of nitrogen brings into sharper focus this underground process at the root of nearly all of Earth's food chain...

UCR biochemist goes to Washington with high-protein corn

Daniel Gallie's findings propose a useful approach to feed the world's growing population Because his research holds promise for efficiently fee...

Bacteria that cause tooth decay able to survive without important biochemical pathway

Leave it to the bacteria that cause tooth decay to be able to live without something all cells were thought to require. Scientists have long believed a certain biochemical pathway involved in the folding and delivery of proteins to cell membranes is essential for survival. Now University of Florida researchers have discovered that Streptococcus mutans, the decay-causing organism that thri...

Precision biochemistry tracks DNA damage in fish

Like coal-mine canaries, fish DNA can serve as a measure of the biological impact of water and sediment pollution--or pollution clean-up. That's one of the conclusions of a new study* by researchers from the Pacific Northwest Research Institute (PNRI), Woods Hole Oceanographic Institution, the University of Maryland and the National Institute of Standards and Technology (NIST). Research ov...