Alzheimer in Biological News

Work in mice will contribute to the study of hereditary diseases that lead to blindness

...d adult, and has studied the response of these cells to a neurodegenerative process induced in the retina by intense light exposure. Parkinson and alzheimer The researcher of the UGR insists that "it is important to get to know the response of the microglial cells against neurodegenerative, because such ...

Neural stem cell differentiation factor discovered

...ecially in the human brain. EGFL7 might also be applied as a neuronal differentiation factor in ischemic insults or neurodegenerative diseases such as alzheimer or Parkinson predict both researchers. Future work will unravel in which diseases EGFL7 can unfold its therapeutic potential. ...

Mitochondria could be a target for therapeutic strategy for Alzheimer's disease patients

...arch. This paper strengthens the concept that mitochondrial permeability pores may be central in mitochondrial and neuronal malfunction relevant to alzheimer disease. Dr. Yan and her colleagues offer new insights into the mechanism underlying amyloid beta (Aβ)-mediated mitochondrial stress through an i...

Mechanism explains link between apolipoprotein E and Alzheimer's disease

... however, the basis for this remains one of the major unanswered questions of disease pathogenesis," writes study author Dr. Gary E. Landreth from the alzheimer Research Laboratory at Case Western Reserve University School of Medicine in Cleveland, Ohio. Dr. Landreth and colleagues sought to unravel the li...

Umbilical cord blood cell therapy in an animal model of Alzheimer's disease

...mers disease in a report entitled, Peripherally administered human umbilical cord blood cells reduce parenchymal and vascular beta-amyloid deposits in alzheimer mice. Previously, challenging observations have reported phenomena suggesting the non-hematologic therapeutic potential of blood stem cells. What i...

Biophysical Society announces 2008 International Travel Awards

...fecting Bacterial Growth. Alex Pervarez-Marn, Stockholm University, Sweden, Time-Resolved Infrared Spectroscopy of pH-Induced Aggregation of the alzheimer Ab1-28 Peptide. Suman Nag, Tata Institute of Fundamental Research, Mumbai, India, Kinetics of Misfolding and Aggregation of Amyloid Proteins. ...

Lipids in the brain an important factor for Alzheimer's disease?

...in the Western world, Alzheimer's disease carries enormous implications for our ageing society. It is generally accepted that the disease is caused by alzheimer peptide (A -peptide) protofibrils. Until now, the conditions under which this type of protofibril is formed and leads to the disease remained unknown....

Highlights from the December 2007 Journal of the American Dietetic Association

...es among Citizen Infants of Immigrant Mothers Poor Nutrient Intakes over a One-Year Follow-Up in Community-Dwelling Older Adults with Early-Stage alzheimer Dementia Compared to Cognitively Intact Matched Controls About Feeding Children: Mealtimes in Childcare Centers in Four Western States Emergen...

Misconceptions about Alzheimer's varies among races, survey suggests

...l is associate director for the Center for Managing Chronic Disease, and lead author of the study, which appears in the September issue of the journal alzheimer Disease and Associated Disorders. Co-authors include J. Scott Roberts, assistant professor in the School of Public Health, and Sara McLaughlin, doctor...

Research team identifies new Alzheimer's gene

...ade publicly available to the research community. The researchers believe that deposition of this data set in the public domain will open a new era in alzheimer research. When a scientist suspects a particular gene or pathway maybe implicated in Alzheimer’s disease, they will use these data to see if there is ...

Scientists identify protein with a crucial role in cell death

...'s disease. A noble stranger... This starting assumption brought two top researchers together: Bart De Strooper, who has extensive experience in alzheimer research and is thus also interested in the causes of Parkinson's disease, and Luca Scorrano, who specializes in the functioning and effect of mitocho...

Case Western Reserve University researchers find protein associated with brain cell death

...on, the study's lead researcher. Her co-investigators are Jessica Koenigsknecht-Talboo, Christian Grommes, C.Y. Daniel Lee and Gary Landreth from the alzheimer Research Laboratory in the Case department of neuroscience. Vav also plays a critical role in the initial microglial response to the plaque. Oxi...

Imaging study links key genetic risk for Alzheimer's disease to myelin breakdown

...with the presence of a key genetic risk factor for alzheimer disease. The findings are detailed in the Januar...lin breakdown is a key contributor to the onset of alzheimer disease later in life. In addition, the study d...e advanced age and the principal genetic risks for alzheimer disease," said Dr. George Bartzokis, professor of ...

The urban evolution lab

...or memory and knowledge. Ever since the disease was first reported by Alois alzheimer − 100 years ago now − scientists have been searching diligently... amyloid plaques. The development of amyloid plaques in the brain tissue of alzheimer patients is a central factor in the search for a therapy for Alzheimer's di...

Researchers discover a new genetic cause of Alzheimer's disease

...or memory and knowledge. Ever since the disease was first reported by Alois alzheimer − 100 years ago now − scientists have been searching diligently... amyloid plaques. The development of amyloid plaques in the brain tissue of alzheimer patients is a central factor in the search for a therapy for Alzheimer's di...