Advanced

Applied Biosystems Introduces Advanced Gene Expression Service Provider Program

Applied Biosystems (NYSE:ABI), an Applera Corporation business, today announced the introduction of the Applied Biosystems Advanced Gene Expression Service Provider Program, a new program for service providers who are interested in accessing Applied Biosystems comprehensive solution for gene expression analysis, including the highly sensitive Expression Array System for whole genome analysis and...

Bevacizumab Combined With Chemotherapy Improves Progression-Free Survival for Patients With Advanced Breast Cancer

Preliminary results from a large, randomized clinical trial for patients with previously untreated recurrent or metastatic breast cancer ?cancer that has spread from the breast to other parts of the body ?show that those patients who received bevacizumab (Avastin? in combination with standard chemotherapy had a longer time period before their cancer progressed than patients who received the same...

Researchers test new therapy for advanced melanoma

Melanoma is a particularly deadly form of skin cancer very resistant to treatment. Researchers at H. Lee Moffitt Cancer Center & Research Institute and the University of South Florida are testing a promising new therapy that prompts the immune system to aid in the fight against melanoma tumors. "This is a milestone clinical trial because it is the first time that electroporation is bei...

Agilent Technologies introduces advanced zebrafish, mouse microarrays for stem cell and developmental biology research

Which is more likely to happen - you being in a car wreck or being bitten by a shark? Those who answered that cars are greater killers win a free trip to the beach. It's really no contest, says a Texas A&M University professor. Your chances of being in a wreck are far greater than being a shark's lunch, says John McEachran, a professor of wildlife and fishery sciences who has studied...

Advanced genomics and proteomics improve the diagnosis and treatment of a deadly lung disease

A team of Howard Hughes Medical Institute (HHMI) scientists has peeled back some of the mystery of how cells are able to turn off genes selectively to control critical events of development. The new insights arise from the first clear molecular images of the structure of Dicer, an enzyme that enables cells to dissect genetic material precisely. The finding, which is reported in the January...

Combination therapy shows promising results in patients with advanced lung cancer

An early phase study pairing an experimental targeted therapy with a common anti-inflammatory produced promising results in patients with advanced lung cancer, researchers at UCLA's Jonsson Cancer Center reported. Pairing the targeted therapy Tarceva with the anti-inflammatory drug Celebrex increased response rates in lung cancer patients by about three-fold, said Dr. Karen Reckamp, an as...

An advanced genetic diagnostic method for multiple myeloma

A researcher at the University of Navarra, Borja Sáez Ochoa, has proposed a new genetic diagnostic method for multiple myeloma (MM), a type of bone marrow cancer, which permits the detection of this disease in earlier stages. The dissertation of this biologist, produced in the Department of Genetics of the School of Sciences of the University of Navarra, and in the Institute of Human Genet...

Molecular differences between early and advanced melanomas could provide new drug targets

The cell-signaling molecule Akt is a primary trigger that leads malignant melanomas on the skin's surface to begin growing vertically beneath the skin and turn into deadly invasive cancers, scientists have found. Understanding this key molecular difference between radial melanomas that spread on the surface of the skin and melanomas that grow vertically and invasively could provide new targets f...

Heavy multivitamin use may be linked to advanced prostate cancer

While regular multivitamin use is not linked with early or localized prostate cancer, taking too many multivitamins may be associated with an increased risk for advanced or fatal prostate cancers, according to a study in the May 16 issue of the Millions of Americans take multivitamins because of a belief in their potential health benefits, e...