Adult in Biological News

Carbon nanoparticles toxic to adult fruit flies but benign to young

PROVIDENCE, R.I. [Brown University] Carbon nanoparticles are widely used in medicine, electronics, optics, materials science and architecture, but their health and environmental impact is not fully understood. In a series of experiments, researchers at Brown University sought to determine how ...

LSUHSC shows for first time infant inhalation of ultrafine air pollution linked to adult lung disease

New Orleans, LA Stephania Cormier, PhD, Associate Professor of Pharmacology at LSU Health Sciences Center New Orleans, has shown for the first time that early exposure to environmentally persistent free radicals (present in airborne ultrafine particulate matter) affects long-term lung function. S...

Plastics chemical retards growth, function of adult reproductive cells

CHAMPAIGN, Ill. Bisphenol A, a chemical widely used in plastics and known to cause reproductive problems in the offspring of pregnant mice exposed to it, also has been found to retard the growth of follicles of adult mice and hinder their production of steroid hormones, researchers report. The...

Stanford scientists turn adult skin cells into muscle and vice versa

In a study featured on the cover of the May issue of The FASEB Journal , researchers describe how they are able to reprogram human adult skin cells into other cell types in order to decipher the elusive mechanisms underlying reprogramming. To demonstrate their point, they transformed human skin c...

Human adult testes cells can become embryonic-like

WASHINGTON, D.C. Using what they say is a relatively simple method, scientists at Georgetown University Medical Center have extracted stem/progenitor cells from testes and have converted them back into pluripotent embryonic-like stem cells. Researchers say that the nave cells are now potentially ...

Single virus used to convert adult cells to embryonic stem cell-like cells

CAMBRIDGE, Mass. (Dec. 15, 2008) Whitehead Institute researchers have greatly simplified the creation of so-called induced pluripotent stem (iPS) cells, cutting the number of viruses used in the reprogramming process from four to one. Scientists hope that these embryonic stem-cell-like cells coul...

Single adult stem cell can self renew, repair tissue damage in live mammal

The first demonstration that a single adult stem cell can self-renew in a mammal was reported at the American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San Francisco. The transplanted adult stem cell and its differentiated descendants restored lost function to mi...

Transporting juvenile salmon hinders adult migration

Scientists have discovered that management efforts intended to assist migrations of salmon and steelhead trout can have unintended consequences for fish populations. Juveniles that are transported downstream on boats can lose the ability to migrate back to their breeding grounds, reducing their su...

Scripps research scientists identify compounds for stem-cell production from adult cells

In the study, the scientists screened known drugs and identified small molecules that could replace conventional reprogramming genes, which can have dangerous side effects. This new process offers a new way to generate stem cells from fibroblasts, a general cell type that is abundant and easily ac...

NIH EUREKA award funds research at WPI aimed at turning adult skin cells into stem-like cells

WORCESTER, Mass. A research team at Worcester Polytechnic Institute (WPI) has received a three-year, $900,000 award from the National Institutes of Health (NIH) for a project aimed at developing a novel way of transforming adult skin cells into stem-like cells. If successful, the research could r...

Children's Memorial Hospital of Chicago receives a grant from BioMarin to support adult PKU outreach

Chicago, IL, Children's Memorial Hospital of Chicago announced today that it has received a grant from BioMarin Pharmaceutical Inc. to support its Adult Phenylketonuria (PKU) Outreach Education Project. The goal of the program is to conduct outreach to PKU patients who are no longer being treat...

Salk researchers reprogram adult stem cells in their natural environment

LA JOLLA, CA In recent years, stem cell researchers have become very adept at manipulating the fate of adult stem cells cultured in the lab. Now, researchers at the Salk Institute for Biological Studies achieved the same feat with adult neural stem cells still in place in the brain. They successf...

UC Davis stem researchers demonstrate safety of gene therapy using adult stem cells

(SACRAMENTO, Calif.) A new study by UC Davis researchers provides evidence that methods using human bone marrow-derived stem cells to deliver gene therapy to cure diseases of the blood, bone marrow and certain types of cancer do not cause the development of tumors or leukemia. The study was publi...

Stem cells and cancer: cancer pathways that also control the adult stem cell population

Speaking today (10 April) at the UK National Stem Cell Network Annual Science Meeting in Edinburgh, Professor Alan Clarke from Cardiff University describes his work to investigate a mechanism that normally drives adult stem cells to repair the intestine. Together with his colleague Owen Sansom fro...

Scientists uncover the potential to control adult stem cells

Research being presented today (10 April) at the UK National Stem Cell Network Annual Science Meeting in Edinburgh represents a step towards the use of Adult Stem Cells (ASCs) to repair damaged tissue. Speaking at the conference in Edinburgh, Professor Cay Kielty of the University of Manchester d...

Hungry mothers risk addiction in their adult children

Babies conceived during a period of famine are at risk of developing addictions later in life, according to new research published in the international journal Addiction. Researchers from the Dutch mental health care organisation, Bouman GGZ, and Erasmus University Rotterdam studied men and women...

Elusive pancreatic stem cells found in adult mice

Just as many scientists had given up the search, researchers have discovered that the pancreas does indeed harbor stem cells with the capacity to generate new insulin-producing beta cells. If the finding made in adult mice holds for humans, the newfound progenitor cells will represent an obvious t...

Scientists study the link between children's nutrition and adult diseases

This release is also available in Spanish . Researchers from the Department of Pediatrics of the University of Granada , in collaboration with another 38 universities and companies from 16 European countries, will study the effects of childrens nutrition on the onset of cardiovascular p...

Mechanism for regulation of growth and differentiation of adult muscle stem cells is revealed

During muscle regeneration, which is a natural response to injury and disease, environmental cues cause adult muscle stem cells (satellite cells) to shift from dormancy to actively building new muscle tissue. Although the signaling pathways controlling muscle regeneration are fairly well known, h...

Young chimps top adult humans in numerical memory

Young chimpanzees have an extraordinary ability to remember numerals that is superior to that of human adults, researchers report in the December 4th issue of Current Biology, a publication of Cell Press. There are still many people, including many biologists, who believe that humans are superi...

New book defines promising young field of adult neurogenesis

COLD SPRING HARBOR, N.Y. Studies of the birth and incorporation of neurons into the brains of mature animalsa process known as adult neurogenesispromise intriguing insights into the mechanisms of normal brain function and into the causes of depression and other psychiatric disorders. A new boo...

Deep into the machinery of adult fragile X

Researchers have reported new insight into the pathology underlying a recently identified neurological disorder that strikes middle-aged adults that is caused by alterations in the same gene that causes fragile X syndrome. Fragile X tremor/ataxia syndrome (FXTAS) overwhelmingly affects males, usua...

Scientists clone mice from adult skin stem cells

For cells that hold so much promise, stem cells' potential has so far gone largely untapped. But new research from Rockefeller University and Howard Hughes Medical Institute scientists now shows that adult stem cells taken from skin can be used to clone mice using a procedure called nuclear transfe...

UW launches study testing adult stem cells for heart damage repair

The University of Wisconsin School of Medicine and Public Health is among the first medical centers in the country taking part in a novel clinical trial investigating if a subject's own stem cells can treat a form of severe coronary artery disease. The trial, just underway at UW Hospital and Clin...

Researchers first to map gene that regulates adult stem cell growth

A new discovery in stem cell research may mean big things for cancer patients in the future. Gary Van Zant, Ph.D., and a research team at the University of Kentucky published their findings today in Nature Genetics, an international scientific journal. The researchers genetically mapped a stem c...

Penn researchers replace organ in adult mice using 'single-parent' stem cells

Researchers at the University of Pennsylvania School of Veterinary Medicine have derived uniparental embryonic stem cells - created from a single donor's eggs or two sperm - and, for the first time, successfully used them to repopulate a damaged organ with healthy cells in adult mice. Their findi...

Experience affects new neuron survival in adult brain; study sheds light on learning, memory

Experience in the early development of new neurons in specific brain regions affects their survival and activity in the adult brain, new research shows. How these new neurons store information about these experiences may explain how they can affect learning and memory in adults. A team of resea...

MIT bioengineer advances survival, promise of adult stem cells

MIT researchers have developed a technique to encourage the survival and growth of adult stem cells, a step that could help realize the therapeutic potential of such cells. Adult stem cells, found in many tissues in the body, are precursor cells for specific cell types. For example, stem cells fo...

Stem cells found in adult hair follicles may provide alternative to embryonic stem cells

Having recently identified the molecular signature of these epidermal neural crest stem cells in the mouse, their research resolves conflicting scientific opinions by showing that these cells are distinctly different from other types of skin-resident stem cells/progenitors. Their work provides a v...

Adolescent but not adult hamsters are more aggressive on low dose of fluoxetine

New research offers tantalizing clues as to why some teenagers taking common anti-depressants may become more aggressive or kill themselves. The research is published in the October Behavioral Neuroscience, which is published by the American Psychological Association (APA). Neuroscientists at th...

Stem cells found in adult skin can be transplanted and function in mouse models of disease

Researchers at The Hospital for Sick Children (SickKids) and the University of Calgary have found that stem cells derived from adult skin can create neural cell types that can be transplanted into and function in mouse models of disease. This research is reported in the June 14, 2006 issue of The J...

With few factors, adult cells take on character of embryonic stem cells

With the introduction of just four factors, researchers have successfully induced differentiated cells taken from mouse embryos or adult mice to behave like embryonic stem cells. The researchers reported their findings in an immediate early publication of the journal Cell. The cells--which the r...

Can you hear me now? Scientists find previously unknown receptors on adult stem cells

For many years, researchers believed that stem cells in the bone marrow spent most of their existence in a slumber-like state, unaware of -- and unaffected by -- the daily battles fought by the body's immune system. Not so. Scientists at the Oklahoma Medical Research Foundation have discovered...

With few factors, adult cells take on character of embryonic stem cells

With the introduction of just four factors, researchers have successfully induced differentiated cells taken from mouse embryos or adult mice to behave like embryonic stem cells. The researchers reported their findings in an immediate early publication of the journal Cell, published by Cell Press. ...

Findings advance use of adult stem cells for replacement bone

In a significant advance for regenerative medicine, researchers at Rice University have discovered a new way to culture adult stem cells from bone marrow such that the cells themselves produce a growth matrix that is rich in important biochemical growth factors. The research, which appears online...

Powerful technique for multiplying adult stem cells may aid therapies

Adult stem cells may be free of the ethical concerns that hamper embryonic stem cell research, but they still pose formidable scientific challenges. Chief among these is the doggedness with which adult stem cells differentiate into mature tissue the moment they're isolated from the body. This makes...

Infections could contribute to adult brain tumours

Infections could play a key role in triggering certain types of adult brain cancer, according to results from a new statistical analysis of the disease. The international study, led by Dr Richard McNally at the University of Newcastle upon Tyne, was funded by Cancer Research UK, the Dutch Cancer...

Infant transplant patients resist infections that kill adult AIDS patients

Investigators have discovered that some type of protective system goes into action in some cases when a baby's immune system is deficient. This discovery indicates a hidden safety net that might have far-reaching consequences for treating diseases of the immune system such as AIDS. The Mayo Clinic-...

Feds give researchers ok for safety test of adult stem cells in patients with heart disease

Researchers at Case Western Reserve University School of Medicine and University Hospitals of Cleveland announced that the Food and Drug Administration (FDA) has approved plans to begin a study to evaluate the safety of using adult stem cells from bone marrow to treat chronic ischemia, a serious fo...

Changes to embryos can elicit change in adult fish

In a study illustrating the apparent linkages between the evolutionary development and embryonic development of species, researchers have uncovered the genetic elements that determine the structure and function of a simple biomechanical system, the lower jaw of the cichlid fish. In addition, they'v...