Improving the potential of cancer vaccines
...10 years of clinical trials, the data suggest that you can induce (cancer) antigen-specific immune respon...lls with chemoagents or a specific antibody. "But you may also deplete the good cells needed for fighting cancer," said Wang. He and his group identified...Identification of specific genes predicts which patients will respond to Hepatitis C treatment
...tment. He is now clear of the virus. "Knowing that you are a responder gives you the courage and the fight to go on. It was devastating, but having the support of my friends and hos...Researchers feed tiny pills of RNA to planarians to identify genes essential for regeneration
...ian biology has much in common to the biology that you and I share," said Sánchez Alvarado, who last month was appointed a Howard Hughes Medical Institute investigator. "This work opens a whole new window to study aspects of human biology that are barely accessible today." The planarians used in these s...Study shows how retinoic acid enters a cell's nucleus
...ed to the toxic doses currently administered. "If you can provide a bus to get retinoic acid into the nucleus more efficiently, then you enhance its ability to act as an anti-carcinogen," says Noy. "It's a rapid transport advantage." He...Gene expands malaria's invasion options
...e, Australia, and the study's senior author. "When you remove sialic acid, you block half the doors. W2mef normally goes in through the receptors with sialic acid, but it can swit...Deep sleep short-circuits brain's grid of connectivity
...appens every night to all of us. Every night, when you fall into deep sleep, your consciousness usually fades." Indeed, research subjects woken early in the night frequently report little or no conscious experience. Later in the night, and especially in the morning hours, subjects report vivid dreams, i...Frog peptides block HIV in lab study
...appens every night to all of us. Every night, when you fall into deep sleep, your consciousness usually fades." Indeed, research subjects woken early in the night frequently report little or no conscious experience. Later in the night, and especially in the morning hours, subjects report vivid dreams, i...Say what? Bacterial conversation stoppers
...associate with humans," Bassler said. "In the gut, you can imagine how the normal microflora might interfere with cell-cell communication to thwart bacterial invaders." Using a chemical communication process called quorum sensing, bacteria converse among themselves to count their numbers and to get the...Promiscuous Catalytic Activity Possessed by Novel Enzyme Structure
... effects it has when it reaches its target. “When you make that so-called hybrid molecule, all the chemi...protein that seems to be able to do reactions that you can find somewhere else in nature, but where people have not been able yet to isolate the proteins,?...Stem cell training program to make its Stanford debut
... effects it has when it reaches its target. “When you make that so-called hybrid molecule, all the chemi...protein that seems to be able to do reactions that you can find somewhere else in nature, but where people have not been able yet to isolate the proteins,?...Micro-molecule plays big role in birth defects
...ncer to AIDS. "There is indirect evidence that if you remove two microRNAs from the human genome, leukemia develops," Harfe said. "We envision our mouse model may be a tool to directly test how microRNAs are involved in human cancers." ...Gene therapy advance treats hemophilia in mouse models
...didate for correction with gene therapy because if you could just raise the factor VIII activity from less than 1 percent of normal to within 5 to 10 percent of normal, the tendency for spontaneous bleeding and need for hospitalization would diminish dramatically," McCray said. "In the mouse model in o...New Scripps Oceanography project to study sediments and ecosystem restoration in Venice lagoon
...ries back in time. Because the sediment is so old, you could expect metals and organic contaminants to be present," said Deheyn, whose experience includes using biological indicators to test for toxins and pollutants in San Diego Bay. As in San Diego's waters, when studying Venice's lagoon Deheyn will u...Fundamental discovery -- Bone fracture
...on mechanisms and deficiencies can be studied. "If you don't know something is important then you can't do anything about it. This is a fundamental and new discovery in an old and well-studied field...Compound from Chinese medicine shows promise in head and neck cancer
...articularly difficult for patients. It affects how you talk, how you swallow and how you breathe," says study author Carol Bradford, M.D., professor of otolaryngology at...Lance Armstrong through a physiological lens: hard training boosts muscle power 8%
...years including victory in the Tour de France, and you might uncover some incredibly important, indeed am...n. But it's also nice to know," he added, "that as you get older that your body becomes wiser in how it does its job and less wasteful in energy usage." C...Virologist finds contagious equine flu in dogs
..."With 50 million pet dogs in this country, even if you have 1 percent mortality, this is going to result in a number of dogs dying from it." The Centers for Disease Control and Prevention (CDC) in Atlanta sequenced the virus' entire genome and found all the segments were from the equine virus. This is...Slipping past the blood brain barrier: Research shows potential treatment for brain cancer
...tion the week of Aug. 22. "The bottom line is, if you can get drugs into the brain, you can cure brain cancer," says William A. Banks, M.D., professor of geriatrics in the department of in...Penguin chicks exposed to human visitors experience spike in stress hormone
...hose in non-visited areas. "In the tourist areas, you can walk among them and they put up with you. But when you walk over the hill to the places where tourists don't go, they're much more skittish. They run away ...Discovering an ecosystem beneath a collapsed Antarctic ice shelf
... the carpet off the floor and finding a layer that you never knew was there." Domack suggests the strong possibility that new species of marine life may be uncovered in continuing analyses of the area as ecosystem experts sample the site. The international expedition was there on a U.S. Antarctic Progra...