Confocal imaging promises early detection of skin cancer
...siTech International. “Confocal microscopy allows you to optically section through objects,?says Dr Sheblee. “It’s like a biopsy without the painful physical cuts and resulting scars, looking at layers slice by slice.?The technology has been around for 50 years, but only recently been used in the life s...Secret of smallpox's success may lead to bioterror cure
...e. "And there has been anecdotal evidence that if you get exposed to smallpox and get vaccinated within ...he mice are given, the less sick they become. "If you give them a million particles, they don't even get sick -- the animals stay healthy," notes Jacobs. ......ur family's ancestors roamed 60,000 years ago? Now you can find out by participating in the world's most ... molecular biophysics and a professor in BIO5. "If you ask around here, you find that every tenth person is building a little family tree at home. They go ...The circadian clock: Understanding nature's timepiece
...s less than half the size of a pencil eraser tells you when to wake up, when to be hungry and when it's time to go to sleep. The same cells also cause you to be disoriented after you've flown across multiple time zones. The human circadian clock, compris...Gene therapy cures inherited liver disease in rats
...pproach would be applicable to many diseases where you are trying to put something back, targeting the liver," he said. He is hesitant to predict when the treatment can be tried in humans. While the viral vector is fairly benign long term, he would like to see one developed that minimizes the body's imm...Brain May Be Less Plastic Than Hoped
...ficult to interpret,?he said. “But in the macaque, you can design lesions and test pharmaceuticals to sort out what kind of reorganization the brain is capable of after, say, a stroke. It's a powerful way to stimulate and study reorganization that may turn out to be beneficial in the future.?/p>...Low oxygen likely made Great Dying worse, greatly delayed recovery
... can go without water for a few days. How long can you go without oxygen, a couple of minutes? There's nothing with a greater evolutionary effect than oxygen." ...Scientists reveal the shape of a protein that helps retroviruses break into cells
... can go without water for a few days. How long can you go without oxygen, a couple of minutes? There's nothing with a greater evolutionary effect than oxygen." ...Unchecked DNA replication drives earliest steps toward cancer
...istar and senior author on the Nature study. "Once you have the initiating event, you will have constant DNA breaks. These DNA breaks create more mutations, leading to tumor progression....Discovery clarifies role of peptide in biological clock
...schedule, these mice looked normal, but as soon as you leave off the lights, they reveal their internal de-synchrony," he said. "The mice showed multiple rhythms, getting up both earlier and earlier and later and later on subsequent days so that their daily activity patterns were splitting apart." Herzo...Gene keeps neural cells on correct developmental path
...y off in non-neuronal tissues, such as skin, where you don't dare express a neuronal gene. But it also allows the full elaboration of the neuronal phenotype from the precursor cell." Led by HHMI associate Nurit Ballas, a postdoctoral fellow in Mandel's lab, the study may advance stem cell research aimed...Too much water may be as dangerous as too little during long-distance athletic events
...distance race may do serious harm rather than keep you safe from injury if you're drinking too much, acco...e and comparing that number to the amount of fluid you consumed throughout. "All serious distance athletes should find out what their rate of fluid loss ...Bush, Cheney and Rumsfeld are now species of slime-mold beetles -- but strictly in homage
...distance race may do serious harm rather than keep you safe from injury if you're drinking too much, acco...e and comparing that number to the amount of fluid you consumed throughout. "All serious distance athletes should find out what their rate of fluid loss ......distance race may do serious harm rather than keep you safe from injury if you're drinking too much, acco...e and comparing that number to the amount of fluid you consumed throughout. "All serious distance athletes should find out what their rate of fluid loss ...AIDS Public Awareness Campaign Expands Following Report Of Rapidly Progressive HIV
...cial, ethnic, age or gender boundaries. It is what you do, not who you are, that puts you at risk for HIV." Individuals who wish to get tested may choose to do so anonymo...Microscopes at microscopic size
... away from the idea that a microscope is something you have to look through to create optical biochips onto which scientists can place biological samples. Special fluorescent chemicals are then used together with tiny light emitting lasers to allow the scientists to analyse the cells or targets within th...To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists
...mon antibiotics ciprofloxacin and rifampicin. "If you inhibit this pathway, the bacteria cannot evolve," says Scripps Research Assistant Professor Floyd Romesberg, Ph.D., who led the study. Since the evolution of resistance is under the control of LexA, compounds that block the protein might prolong th...Future diabetes drugs may target new protein interaction
...erent proteins, and it's just this one interaction you would want to prevent." But, he says, PGC1 has an unusually close relationship with sirtuin1 that may make for relatively easy picking. PGC1, unlike the vast majority of proteins, only uses sirtuin1 to remove its "decorations," called acetyl groups.......erent proteins, and it's just this one interaction you would want to prevent." But, he says, PGC1 has an unusually close relationship with sirtuin1 that may make for relatively easy picking. PGC1, unlike the vast majority of proteins, only uses sirtuin1 to remove its "decorations," called acetyl groups....Computational verification of protein-protein interactions by orthologous co-expression
...erent proteins, and it's just this one interaction you would want to prevent." But, he says, PGC1 has an unusually close relationship with sirtuin1 that may make for relatively easy picking. PGC1, unlike the vast majority of proteins, only uses sirtuin1 to remove its "decorations," called acetyl groups....