Hybrid molecule causes cancer cells to self-destruct
...ue of the journal Chemistry & Biology, has not yet been tested on animals or humans. Nevertheless, they believe it represents a promising new strategy for fighting the deadly disease. "For a long time, cancer researchers did not pay much attention to the use of sugars in fighting cancer," said Gop...Columbia scientists determine 3-dimensional structure of cell's 'fuel gauge'
.... Dr. Shapiro explained that researchers do not yet know how to activate AMPK without activating other proteins and causing potentially toxic side effects. However, he notes that this development in understanding the atomic resolution structure of the protein provides researchers a powerful new tool ...Common gene version optimizes thinking -- but with a possible downside
...e that optimizes their brain's thinking circuitry, yet also appears to increase risk for schizophrenia, a severe mental illness marked by impaired thinking, scientists at the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH) have discovered. The seeming paradox emerged fro...Anti-wrinkle compound causes pathological reaction in skin cells
...nd baby lotions, although the way they work is not yet understood. In vitro tests conducted by Dr. Marceau’s team revealed that the application of DMAE induces a quick and spectacular swelling of skin cell vacuoles called fibroblasts, which act as reservoirs and interface between the inside and the ou...A new study of living cells could revolutionize the way we test drugs
... hoped for, the electrical signal was the smallest yet detected from a living cell, around 100 times smaller than anything previously detected. It added up to an electrical current of just 10 moving electrons. It has given the team confidence that equipment sensitive enough to measure a cell’s heartbeat ...Gene elevating breast cancer risk also causes prostate cancer
...theless disposed to believe that the evaluation of yet other biologically significant factors will in time improve the situation. "Hopefully, increased knowledge of underlying mechanisms will provide better conditions for cancer prevention, diagnostics and treatment," Winqvist says. ...Analysis of rhesus monkey genome uncovers genetic differences with humans, chimps
...imate species share about 93 percent of their DNA, yet have some significant differences among their gene...related genes, as well as genes with functions not yet fully known. In addition to comparing the rhesus with the chimp and human genomes, the group als...New technologies coming too fast for Indian farmers
... While Bt seed exacerbates the problem by creating yet another option, the farming troubles predate its introduction. In the late 1990s, there was an epidemic of farmer suicide in the Warangal District. Many farmers are deeply in debt and have been for generations. Stone's study shows that the farmer...A rarity among arachnids, whip spiders have a sociable family life
...achnids with social tendencies, Rayor said she has yet to witness amblypygids intentionally sharing prey. More than 100 amblypygid species live in tropical areas worldwide. These arachnids, whose bodies range from one-eighth to about one and three-quarters inches long, have two elongated pedipalps (lik...New mechanism for nutrient uptake discovered
...ered to work in this way." The scientists don't yet know what triggers the rapid shut-off. They think it might be a very common regulatory event called phosphorylation, where a phosphate molecule is introduced to another molecule, changing the latter, and preparing it for a chemical reaction. They hav...New species of snapper discovered in Brazil
...ecies spend some of their lives in these different yet connected habitats," Lindeman said. "That's why it's so important to develop integrated conservation strategies that include mangroves, deep reefs and other interdependent ecosystems." ......e. This takes 1 minute. It's as simple as that, yet nobody's ever done it before. The method is so new that the University of Rochester filed patents for it in 2004 and 2006. In May 2005, Professor Rothberg created a company called Diffinity Genomics, Inc. with two partners to further study and commer...Scientists clone mice from adult skin stem cells
...ng a cloned mouse. Although this procedure has not yet successfully generated human embryonic stem cell lines, once technological hurdles are overcome, it may be possible in the future to use a patient's skin stem cells to tailor make embryonic stem cell lines, circumventing the problem of immune rejecti...Autism gene identified by researchers at Yale working with a global research consortium
...linked to autism susceptibility. That gene has not yet been pinpointed. Researchers speculate that there may be five or six major genes and as many as 30 other genes involved in autism. If a child has more of these genes, there is a higher chance of being born with autism or a more severe form of the...Grape expectations for healthier wine
... Agriculture, doi 10.1002/jsfa.2780). It is not yet known why antioxidant levels increase, but because these compounds are up-regulated in response to environmental stress in plant cells, it could be that the ozone is perceived as a biochemical insult. Andrew Waterhouse, Chair of the Department of ...Fighting to keep Darwin in the classroom
...n remains the central unifying idea in biology and yet is still a source of contention and confusion in the classroom. In Outreach and Education in Evolution, we'll cover the gamut, from molecules to ecosystems and from 'intelligent design' to natural selection. We aim to make a big difference in evolu...Surgeons develop simpler way to cure atrial fibrillation
...ve as Cox-maze III for curing atrial fibrillation, yet takes one-third the time to perform. "The older Cox-maze procedure was a very complicated operation, and very few surgeons were willing to do it," Damiano says. "So we started working on new technology and helped develop an effective ablation devi...Scientists sequence genome of parasite responsible for common sexually transmitted infection
...on. "Women are the population most affected by it, yet routine gynecological check-ups do not test for this particular infection, and it's not an STI that generally requires public health notification under state statutes. By better understanding the parasite's genetic structure, we hope to better unders...Phthalates now linked to fat, related health risks
... explanation," Stahlhut said. "While we can’t say yet that phthalates are a definite cause, I am certain they are on the list of chemicals that demands careful study." Phthalates have been widely used for more than 50 years, but only recently implicated as a possible health risk in people. Animal stu......navigation, although just how this is done has not yet been clarified. However, the discovery of iron-containing structures in the beaks of homing pigeons in a new study (1) by Gerta Fleissner and her colleagues at the University of Frankfurt offers a promising insight into this complex topic. The arti...