Technique offers new view of dynamic biological landscape
... of Toronto, described initial studies of E-MAP in yeast in the November 4, 2005, issue of the journal Cel... growth in combination with all other genes in the yeast genome. "The one-to-one method has been an extremely powerful way of studying biological systems," s...Chlamydia parasite lives off our fat
... proteins were screened for those that targeted to yeast intracellular organelles. They identified four proteins that were specifically recruited to lipid droplets. The researchers found that Chlamydia not only directs lipid droplets to its protective vacuole but also causes the proliferation of new lipi...Fitting in: Newly evolved genes adopt a variety of strategies to remain in the gene pool
...ey classified duplicate pairs of genes involved in yeast metabolism into four functional categories: (1) b...Technology in Zurich. "We show that, at least for yeast metabolism, the persistence of the duplicated fraction of the genome can be better explained with an...Novel enzyme offers new look at gene regulation
...ne, or a trimethyl group. Secondly, common baker's yeast does not have LSD1, although it does have proteins...emethylase 1A. A similar protein exists in baker's yeast and has the potential to remove trimethyl groups. JmjC is only a section of the entire JHDM1A prote...Same-sex mating by fungi spawned infection outbreak, evidence suggests
Same-sex mating between two less harmful yeast strains might have spawned an outbreak of disease ...roup suggested a possible explanation: the related yeast C. neoformans can undergo same-sex mating between two alpha partners. Among clinical and environmen...Researchers quantify more noise in gene expression
...her types of cells and other species. "Individual yeast cells exist at various stages of their growth cycl...t and a co-author of the study. "In this case, one yeast cell may be preparing to divide, another may be the result of a recent division, and the phenotypes ...New technique multiplies life span in simple organisms
...hat increase the activity of human homologs of the yeast SCH9 and RAS2 genes play central roles in many human cancers." Homologs are genes descended from a common ancestral DNA sequence. Joining with researchers at the USC Norris Comprehensive Cancer Center, Longo is studying the feasibility of reducing o...Bacterial protein mimics host to cripple defenses
...bles PCD in a variety of susceptible plants and in yeast (a single-celled ancestor of both plants and animals). Abramovitch and Martin compared AvrPtoB's amino acid sequence to known proteins in other microbes and in higher organisms, but found no matches that might hint at how the protein works at the mol...Plant gene related to cancer treatment may foster new oncology drugs
...ransports auxin out of plant cells and also out of yeast and mammalian cells. In the Plant Cell study, they found that other PGP proteins move auxin into cells. "Auxin molecules essentially are pulled through the cell membrane by PGP transport proteins," Murphy said. "It's an energetic process that happen...CO2 sensing proves critical for fungal pathogens to adapt to life in air and human hosts
...ential for superficial (skin) infections, in which yeast must be able to grow despite significantly lowered CO2 levels present at the skin surface. Based on their findings, the authors conclude that CO2 sensing is a vital mediator of fungal virulence in different host environments--for example, at differen...New study to explore cellular circuitry
... a type of yeast. Although a single-celled fungus, yeast shares many genetic traits with humans, making it ... Biophysics have designed a one-of-a-kind "genomic yeast library" that allows for high-speed, systemic examination of the purpose of each protein in the yeas...Prions rapidly 'remodel' good protein into bad, Brown study shows
...iochemistry, conducted the research using Sup35, a yeast protein similar to the human prion protein PrP. T...ry, very rapid change." After the conversion, the yeast cells remained healthy but had new characteristics. This survival supports the theory that prions ha...Scientists get first glimpse at how plants, most animals repair UV-damaged DNA
...ibians, marsupials, and even bacteria, viruses and yeast ?retained a greater ability to repair such damage. Since the 1940s, scientists have been trying to understand how the DNA in plants and some animals can be damaged by UV light, and then ?seemingly ?repaired by visible light. In the 1960s, they ident...North & South American researchers find architectural abnormalities in T. cruzi ribosome
... organisms. "In reconstructions of ribosomes from yeast to rabbits to humans, one essentially sees the same architecture," said Frank. "It lulled us into the belief that once you've seen one ribosome, you've seen them all. It was a total surprise to see such a different structure." Last year, Levin trave...After the yeast is gone bacteria continue to develop flavor of sparkling wine
...g wine production requires addition of sucrose and yeast strains to the base wine for a second fermentation...eted the Cava wine is aged in the bottles with the yeast for at least nine months, or longer for premium quality wines. During aging, substantial chemical ch...Possible treatment found for 'chemobrain'
...uirts, two roundworms, over a dozen fungi, baker’s yeast and the bacterium Escherichia coli. Organisms currently in the NHGRI sequencing pipeline include: macaque, orangutan, cow, platypus, red flour beetle, several additional species of fungi and domestic cat. A complete list of organisms and their sequen...NHGRI Selects 13 More Organisms for Genome Sequencing
...uirts, two roundworms, over a dozen fungi, baker’s yeast and the bacterium Escherichia coli. Organisms currently in the NHGRI sequencing pipeline include: macaque, orangutan, cow, platypus, red flour beetle, several additional species of fungi and domestic cat. A complete list of organisms and their sequen...Researchers create functioning artificial proteins using nature's rules
...be to put them back into a living organism such as yeast or fruit flies and see how they compete with natural proteins in an evolutionary sense." Other UT Southwestern researchers involved in the work are lead authors Michael Socolich, HHMI research specialist, and Dr. William Russ, assistant instructor o......eal prion. To do this, Krishnan took a variety of yeast prion strains and modified them in such a way that...th tails. Remarkably, the same prion from the same yeast species could sometimes fold differently, and this fold would form its own cascade of interactions. ......tory sites for about one-third of the genes in the yeast genome - a success rate as good as or better than other current techniques. "The next step is to test this approach on different organisms, including microbes and vertebrates," Fidelis said. The growing number of organisms whose genomes have been se...