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Tag: "wrong" at biology news

Mouse brain cells rapidly recover after Alzheimer's plaques are cleared

...ition."For example, we'd like to know what's going wrong in the nerve cellbranches that get these swellings," Holtzman says. "Is it really acellular transport problem, or do the swellings result from theplaques' effects on nearby support cells? Or is it something else?"...

Key molecule in plant photo-protection identified

...ition."For example, we'd like to know what's going wrong in the nerve cellbranches that get these swellings," Holtzman says. "Is it really acellular transport problem, or do the swellings result from theplaques' effects on nearby support cells? Or is it something else?"...

Timing is everything: First step in protein building revealed

...disease largely as anincorrect timing event -- the wrong thing happening at the wrong time,or the lack of the right thing."As a result, Lorsch studies the timing of how the ribosome comp...

Another Look Finds Promising Proteomics Test is Not Biologically Plausible

...chers present a “cautionary tale?about what may go wrong when using the fledgling science of proteomics to devise a diagnostic test for cancer. In the February 16 issue of the Journal of the National Cancer Institute, researchers from The University of Texas M. D. Anderson Cancer Center detail why an expe...

New species from old data

...chers present a “cautionary tale?about what may go wrong when using the fledgling science of proteomics to devise a diagnostic test for cancer. In the February 16 issue of the Journal of the National Cancer Institute, researchers from The University of Texas M. D. Anderson Cancer Center detail why an expe...

Cracking the olfactory code in bees

...chers present a “cautionary tale?about what may go wrong when using the fledgling science of proteomics to devise a diagnostic test for cancer. In the February 16 issue of the Journal of the National Cancer Institute, researchers from The University of Texas M. D. Anderson Cancer Center detail why an expe...

Signaling protein builds bigger, better bones in mice

...chers present a “cautionary tale?about what may go wrong when using the fledgling science of proteomics to devise a diagnostic test for cancer. In the February 16 issue of the Journal of the National Cancer Institute, researchers from The University of Texas M. D. Anderson Cancer Center detail why an expe...

The secret lives of whales

...rchers have been thinking about whale herds at the wrong scales, which has been constrained by the limitations of their recording and visual observation abilities. “Suddenly you realize that the whale’s sense of scale is ocean basin sized —one song note is 20 miles long and can illuminate the entire basin,...

Scientists discover the cellular roots of graying hair

..., turning into fullycommitted pigment cells in the wrong place within the hair follicle,where they are usel...here the stem cellsresided. Since they were in the wrong place, the pigmented cells likelydid nothing to maintain the mice’s hair color.To see if the cells b...

Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery

..., turning into fullycommitted pigment cells in the wrong place within the hair follicle,where they are usel...here the stem cellsresided. Since they were in the wrong place, the pigmented cells likelydid nothing to maintain the mice’s hair color.To see if the cells b...

Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.

..., turning into fullycommitted pigment cells in the wrong place within the hair follicle,where they are usel...here the stem cellsresided. Since they were in the wrong place, the pigmented cells likelydid nothing to maintain the mice’s hair color.To see if the cells b...

Multi-purpose protein regulates new protein synthesis and immune cell development

...pile up in the ER membrane, or when something goes wrong with the folding process, the entire system can get clogged with unfolded proteins. To prevent this, the cell activates the unfolded protein response (UPR). "The UPR has three main aspects," Kaufman explains. "First, it signals the nucleus to stop s...

Insight into DNA's 'weakest links' may yield clues to cancer biology

...may ultimately help us better understand what goes wrong in cancer cells, an important step in developing a better plan of attack against the disease," Petes added. ...

Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol

...le activity. Ueno theorizes that if something goes wrong during division - such as if Taxol is interrupting spindle assembly - CDK will become more active in an attempt to correct the problem. Working with the Sysmex Corporation of Kobe, Japan, the researchers devised a test to measure CDK activity and th...

Cellular Defects in Premature Aging Disease are Reversible

...prevent the splicing machinery from cutting in the wrong place. "You can think of it as a molecular Band-Aid®," said Misteli. The researchers inserted their oligonucleotides into the progeria cells and observed that after four days almost all the mutant lamin A transcripts had been eliminated and replaced ...

At the molecular level, the predator is the prey

...uthors. "If the channels change too much or in the wrong way, they can't perform their basic, everyday functions. Sodium channel genes in different vertebrates are virtually identical to each other, but not in these snakes. We're finding a molecular arms race is driving rapid and repeated changes in the ge...

Determining The Fate Of Cells In The Human Body

...ndrome. "By studying a disease in which things go wrong at the cellular level, we gain insight into how to correct these errors," said Dr. Firulli, who also is a molecular biologist at the medical school's Herman B Wells Center for Pediatric Research. "From a pediatrics perspective -- there are many cong...

New understanding of cell movement may yield ways to brake cancer's spread

...oo much cell movement, or from cells moving in the wrong direction and to the wrong place." Dr. Vuori and her team found a molecule called DOCK180, a key signaling protein that binds ...

Genetic links could unlock clues to leading cause of blindness

...n said most people don't even realize something is wrong until they detect changes in their vision. The disease can be controlled, but there is no known way to reverse the vision loss it causes. Knowing more about the earliest predictors of macular degeneration could help doctors treat the disease before ...

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

...uickly, because if the bacteria reproduce with the wrong methylation pattern, gene expression will be foiled and they will lose their virulence. "For the first time, using the 3-D crystal structure, we have been able to see the specific Dam structure in action, including the way it binds to the DNA and mo...

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