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Tag: "worm" at biology news

The secret to longevity in tubeworms

...ures its own long-term survival. The sulfide this worm needs is created by a consortium of bacteria and a... sea cold sediments surrounding the seep where the worm lives. These chemoautotrophs use energy from hydrocarbons to reduce sulfate to sulfide, which L. luy...

Yale Scientists Find MicroRNA Regulates Ras Cancer Gene

...to differentiate into the normal structures of the worm ?instead they make an excess of their cells. After identifying let-7 as a cell division regulator, Slack's team used bioinformatics and found the relationship to Ras. Let-7 in humans is identical to the sequence in the worm, and both binding site an...

Critical role in programmed cell death identified

...tochondria, the cellular power plant, in prompting worm cells to self destruct. These results unify cell d... The researchers demonstrated that when they cause worm mitochondria to fragment without instructing cells to die, the cells still die and when they block f...

Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits

... total of 14,145 yeast (Saccharomyces cerevisiae), worm (Caenorhabditis elegans), and fly (Drosophila mela...did not find in yeast a network they found in both worm and fly that is involved in the guidance of nerve cell axons to their synaptic targets, or junctions...

Stealth Worms May Improve Insect Pest Control

Nematodes comprise a worm family so large it literally covers the earth. They range in size from less than a micron in length to as much as 26 feet. Worldwide interest has begun to focus on microscopic nematodes that live with symbiotic bacteria. "We study these nematodes -- ...

Program finds lost genes in nematode genome

... software that he has developed to the genome of a worm and has found 150 genes that were missed by previous genome analysis methods. Moreover, using the software, he and his colleagues have developed predictions for the existence of a whopping 1119 more genes. Michael Brent, Ph.D., Washington University...

Researchers identify new genes that regulate aging

...ning the genome of Caenorhabditis elegans, a small worm that is used as a model organism in genetics studies. The findings are reported in the inaugural issue of PLoS Genetics. Each of the 23 genes somehow normally acts to reduce longevity, whereas inhibiting any one of them increases lifespan. For examp...

Novel plague virulence factor identified

...wed that the interaction between Y. pestis and the worm is quite similar to what occurs in mammals, includ...thogenesis system using the Caenorhabditis elegans worm can accelerate the process of better understanding Y. pestis pathogenesis. The shorter time and incr...

New Look at DNA Hints at Origin of UV Damage

...wed that the interaction between Y. pestis and the worm is quite similar to what occurs in mammals, includ...thogenesis system using the Caenorhabditis elegans worm can accelerate the process of better understanding Y. pestis pathogenesis. The shorter time and incr...

UCLA scientists reveal how Nipah virus infects cells

... Nipah protein to part of a human antibody, like a worm on a fishing hook. When they placed this bait on cells at risk for Nipah infection, the antibody attached to a receptor on the cell surface. When placed on Nipah-resistant cells, however, the bait did not bind to the cell. The scientists used an ins...

Tiny roundworm's telomeres help scientists to tease apart different types of aging

... with longer telomeres live longer? If not, how do worm cells and by extension non-dividing human cells, s...ts began their work almost nothing was known about worm telomeres. "We had to start at the very beginning. But now we know that C. elegans is the perfect mo...

Regenerating worms help elucidate stem cell biology

...sely, and found that when they amputated part of a worm where the gene had been turned off, the stem cells...at will be needed to establish whether this humble worm can illuminate the mechanisms underlying the unique biology of stem cells. ...

The earliest animals had human-like genes

...v Arendt's group is doing this with a small marine worm called Platynereis dumerlii. "Similar animals are ...from studies of the fly," Arendt says. "The marine worm might well give us an even better look at important conserved processes. Another thing that this has...

MicroRNA gene that regulates lifespan found by Yale scientists

...e simple, but genetically well-studied, C. elegans worm and found genes that are directly involved in dete...ations in these genes alter both the timing of the worm development stages-- and the worm lifespan. C. elegans has been the premier model organism for stu...

New understanding of regeneration gained by Forsyth scientists

...e worms are cut in half, the bottom section of the worm grows a head and the upper section a tail. Scientists have suspected that the ability of previously adjacent cells (on either side of the cut) to adopt radically different fates, as is the case with planaria where the cells have to decide whether to...

Evolutionary conservation of a mechanism of longevity from worms to mammals

...t yet clear whether genes involved in aging in the worm have a similar role in mammals. In a recent study, Dr. Hekimi and colleagues of McGill University (Canada) report that inactivation of the gene mclk1, the murine ortholog of the C. elegans gene clk-1, results in increased cellular fitness and prolon...

Worms know bad food when they smell it

... the laboratory animal C. elegans, a microscopic worm with only 302 neurons. The work suggests that the ... of bacteria. As it writhes through its world, the worm might meet up with hundreds of different species of bacteria in as little as five minutes. But while...

Worm hormone discovery may aid fight against parasitic disease

...n humans ?findings that one day may help eradicate worm infections that afflict a third of the world's pop...ction of Caenorhabditis elegans, a common research worm about the size of a pinhead. In a study available online and appearing in the March 24 issue of th...

For the first time: Longevity modulated without disrupting life-sustaining function

..., Ph.D., Dillin's team identified a protein in the worm Caenorhabditis elegans that allowed them to do just that. The protein is encoded by the Smk-1 gene. "Smk-1 is the first known gene that regulates longevity without affecting other vital functions of the insulin signaling pathway," said Wolff. Under...

Resveratrol prolongs lifespan and delays onset of aging-related traits in a short-lived vertebrate

... non-vertebrate model organisms such as yeast, the worm C. elegans, and the fruit fly Drosophila. However,...-long pharmacological trials were performed in the worm or fly model organisms because of their very small size, very short natural lifespan, and affordable...

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