Study provides insight into cellular defenses against genetic mutation
... made intuitive leaps in the understanding how NMD works with translation, the second phase of gene express...e paper demonstrated for the first time that CBP80 works by activating a protein factor known to drive NMD called human up-frameshift (hUpf) protein 1. A M...Anthrax stops body from fighting back, study shows
...fighting a losing battle." And inhalation anthrax works fast, which is one of the reasons why it is usuall...usually fatal. Knowledge about anthrax and how it works has improved since then, too, Hanna said. Now doctors know what anthrax looks like and what publiche...Researchers learn how blood vessel cells cope with their pressure-packed job
...Rho is a very important molecule," said Chien. "It works in response to, and in concert with, physical stretching to generate the healthy alignment of stress fibers." Indeed, when Chien's group used a genetic technique to increase the activity of Rho, those cells grew stress fibers in the healthy direction...Protein behind autumn color splendor identified
...n Jansson, and Christiane Funk. Grzegorz Jackowski works at Adam Mickiewicz University in Poznan; among the UPSC scientists, Stefan Jansson works at the Department of Plant Physiology and the others at the Department of Biochemistry. The article ...New molecule may aid in production of biofuels and fungi-resistant plants
... up the degradation of chitin by chitinases. CBP21 works by binding to chitin through highly specific interactions that disrupt the chitin structure making the individual sugar chains in the chitin polymer more amenable to enzymatic degradation. The discovery of this new protein that participates in chiti...Careless reporting on HIV 'could cost lives'
...s. Mills, who used to run clinical trials but now works on human rights aspects of HIV trials, acknowledges that it is difficult to say what led the Cambodian prime minister and Cameroon's Ministry of Public Heath to close the trials down. But he believes the media reports combined with activists' protes...New insights into the software of life
...will transform our understanding of how our genome works to produce a complex organism like a human being. The findings of the consortium 'FANTOM', led by the Genomic Sciences Center, RIKEN Yokohama Institute and Genome Science Laboratory and RIKEN Wako Institute, will be published today in two papers in...Breath of the dragon: ERS-2 and Envisat reveal impact of economic growth on China's air quality
...in six days SCIAMACHY is a spectrometer, and it works by measuring sunlight - either transmitted, reflected or scattered by the Earth's atmosphere or surface in the ultraviolet, visible and near infrared regions. Mathematical inversion of these data yields the amounts and distribution of trace gases, oz...Researchers offer proof-of-concept for Altered Nuclear Transfer
...udy to show that altered nuclear transfer not only works but is extremely efficient." First proposed by William Hurlbut, Stanford University professor and member of the President's Council on Bioethics, ANT has been described as an ethical alternative to somatic cell nuclear transfer (SCNT), also known as...Getting an evolutionary handle on life after reproduction
...the first experimental confirmation that evolution works selectively on those aspects of life history that directly affect fitness. They expand on their ongoing investigations of the life history of guppies confronting different predatory threats in Trinidad. Individuals facing different mortality threats...Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, Stanford study finds
...t, Rando said that no matter how well gene therapy works in an isolated muscle, researchers still must figure out how to get that gene to muscles throughout the body. Despite the remaining hurdles, both Rando and Calos said that their study is a step towards eventually treating muscular dystrophy and other...Scientists determine structure of enzyme that disrupts bacterial virulence
...nt pathway than current antibiotics." The enzyme works by disrupting the ability of certain bacteria to sense their own population growth ?the key to triggering genes that can increase virulence. In order to sense the size of their own populations, certain bacteria produce small molecules called N-acyl h...Anti-cancer drugs may hold promise for premature aging disorder
...r like finding out that the key to your house also works in the ignition of your car," said NHGRI Director Francis S. Collins, M.D., Ph.D., who is the study's senior author. The new work involved using FTIs to treat skin cells taken from progeria patients and grown in laboratory conditions. If upcoming st...Bacterial protein mimics host to cripple defenses
...ound no matches that might hint at how the protein works at the molecular level. "We had some biochemical clues to what AvrPtoB was doing, but getting the three-dimensional crystal structure was really key," Martin explained. To find that structure, Martin and Abramovitch worked with collaborators at Roc...The shape of things to come: Morphology database going global
...ir research. It's a matter of having a system that works well with lots of interesting images. That will go a long way to change people's attitudes." Because journals often do not publish all the images that illustrate an article, researchers now must go to a museum or depository to view the specimens or ...University of Arizona plant scientists to unravel maize genome
... Professor in the department of plant sciences who works on enhancing the nutritional value of corn. "The cereals are very closely related to each other, so we can transfer a lot of what we learn about gene function in maize to other crops." One important goal is to enhance drought resistance in corn and...Viagra's hidden help for wildlife
...ine, the men we interviewed chose the product that works best." These findings are consistent with previous research by the von Hippels showing evidence of a post-Viagra decline during the 1990s in the harvesting of three species used in TCM impotence treatments. The pair attributed some of this decl...Blocking the nerve receptor EP1 in mouse models reduces brain damage caused by stroke
...by stroke," he added. "And they show that ONO-8713 works specifically at that receptor." Finally, the Hopkins scientists showed that stimulation of EP1 receptors triggers the damage caused when blood flow is suddenly restored after a stroke. The team blocked blood flow in one of the main arteries feeding ...Novel protein complex enables survival in hostile environment
... in the first place?" A clue comes from published works by Robert White, professor of biochemistry at Virginia Tech, who studies how metabolic systems evolved and collaborates with Mukhopadhyay. "It is possible that M. jannaschii had this enzyme for cofactor biosynthesis and having it in advance gave the ...Penn Surgeons Use Completely Robotic Surgery to Successfully Treat Prostate Cancer
...of the robotic arms holds a tiny video camera, one works as a retractor and the other two replicate the surgeon’s exact hand movements. The camera and instruments are inserted through small keyhole incisions in the patient’s abdomen. The surgeon then directs the robotic instruments to dissect the prostate ...