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Tag: "works" at biology news

Chemical 'band-aid' prevents heart failure in mice with muscular dystrophy

...mice with other types of dystrophies and see if it works as well when given as injections, rather than infusions. Metzger emphasizes that it is uncertain whether P188 will have any clinical use in patients with muscular dystrophy. The material has been used for 24 hours to 72 hours in a phase III clinical...

'Shifty-eyed' Monkeys Offer Window Into Brain's Social Reflexes

...tter understand how processing of social attention works in the brain, and how it can go awry in such disorders as autism. Such basic studies, said the neurobiologists, could lead to better treatments for autism and better methods to teach autistic children. The researchers, post-doctoral fellow Robert De...

Boosting The BCG Vaccine To Beat Tuberculosis

...er T cell-mediated immunity. Because listeriolysin works optimally at a pH of 5.8, the researchers also deleted the urease C gene of BCG, which normally plays a role in pH neutralization of the phagosome. The lack of urease C allows phagosomal acidification and provides an ideal pH environment for listerio...

Researchers Discover Ancient Origins Of Tuberculosis-causing Bacteria

...er T cell-mediated immunity. Because listeriolysin works optimally at a pH of 5.8, the researchers also deleted the urease C gene of BCG, which normally plays a role in pH neutralization of the phagosome. The lack of urease C allows phagosomal acidification and provides an ideal pH environment for listerio...

Agilent Technologies Introduces First Commercial Mouse Microarray for Comparative Genomic Hybridization Research

...er T cell-mediated immunity. Because listeriolysin works optimally at a pH of 5.8, the researchers also deleted the urease C gene of BCG, which normally plays a role in pH neutralization of the phagosome. The lack of urease C allows phagosomal acidification and provides an ideal pH environment for listerio...

Molecular miners find pain relief drugs from the sea

...1 is that eliminating neuropathic pain is where it works best. BACKGROUND Associate Professor Livett and his colleagues first discovered ACV1 in 2003 while studying the toxins produced in the venom of Conus victoriae, a marine cone snail found in tropical waters off the coast of Australia. All cone snai...

Envisat and ERS-2 reveal hidden side of Hurricane Rita

...s using its radar scatterometer. This instrument works by firing a trio of high-frequency radar beams down to the ocean, then analysing the pattern of backscatter reflected up again. Wind-driven ripples on the ocean surface modify the radar backscatter, and as the energy in these ripples increases with w...

New imaging technology shown to detect pancreatic inflammation in type 1 diabetes

...is, Ph.D., a former Joslin research fellow who now works at the BSRC Alexander Fleming Institute of Immunology in Greece, and Eric Swart and Umar Mahmood, M.D., Ph.D., from MGH. In this study, the Joslin and MGH researchers used a new imaging technique to reveal the otherwise undetectable inflammation of ...

UIC researchers show protein routes messages in nerve cells

...napse called the neuromuscular junction in the fly works much like synapses in human brain cells. "We can quickly mutate the flies," said Featherstone. "We looked among thousands of them for those without the glutamate receptors in the right place at the right time. Then we knew that the gene we mutated c...

York scientists warn of dramatic impact of climate change on Africa

...e we used is called a genetic algorithm because it works in a similar way to the effect of evolution on chr...aley, a French palaeobotanist from Montpellier who works on past climate change in West Africa, he immediately drew parallels with events in the last Ice Age...

Research suggests fitness of Florida panthers improved by limited breeding with Texas animals

...al Preserve, he said. Pimm, whose research group works in the Everglades each year, said some scientists have erroneously tended to "look at a map and say, 'because this species isn't here [on the map], then it can't be here.'" Pimm noted the case of a panther biologist who he said was dismissed from hi...

Aloe vera coating may prolong freshness, safety of fruits and vegetables

...or in taste. The researchers believe that the gel works through a combination of mechanisms. Composed mostly of polysaccharides, the gel appears to act as a natural barrier to moisture and oxygen, which can speed food deterioration. But the gel also enhances food safety, the scientists say. Based on previ...

Muscle repair: Making a good system better, faster; implications for aging, disease

...e repair. Understanding how the plasminogen system works in skeletal muscle may give some clues to improving repair of different tissues, especially heart, which is similar in many ways to skeletal muscle. ...

Scientists uncover new clues about brain function in human behavior

... fear response. The medial-prefrontal cortex still works and in fact it is working over-time because it may be the only thing that still regulates the amygdala in Williams Syndrome." ...

Researchers discover how tumor suppressor gene works

...many genes that promote cell growth. The p16 gene works by producing a protein that attaches to the enzymes, preventing them from performing their function. When the researchers added the p16 protein to colonies of cancer cells in culture, it diminished the size of many colonies, wiping out some of them. ...

Gaining ground in the race against antibiotic resistance

... that was not the case here. "This evolved enzyme works better against cephalexin and with the same efficiency on other antibiotics, as well," said Vila. In fact, the mutant enzyme inactivated seven other cephalosporins as efficiently as or better than the original enzyme. "So it hasn't lost anything, and...

Clearing jams in copy machinery

... have more). As the ring-shaped beta sliding clamp works its way along the DNA double helix, a network of proteins work together to unwind the two strands. Polymerases then add, in assembly line fashion, nucleotide bases -- the building blocks that make up DNA -- to convert the now-single-stranded templat...

Computers close in on protein structure prediction

...oped several years ago in Baker's lab. The program works on the premise that proteins collapse into their lowest energy state, like a ball that rolls down a hill until it comes to rest on level ground. The energies of hundreds of thousands of possible shapes generated by the computer are computed, and the ...

New technique could alter field of mouse genetics

...use in mice and other vertebrates. If the new tool works as they expect, it will speed understanding of gen...day out. It's fairly rare to get a transposon that works on a large scale in an effective way. This looks very promising." Transposons have been used in mic...

Virus uses tiny RNA to evade the immune system

...in structure is diced into a microRNA segment that works with another complex to disable other messenger RNAs with complementary sequences. Among several dozen predicted microRNAs, the top candidate turned out to be abundantly expressed in human cells infected with SV40. Sullivan soon found the target of...

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