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Tag: "works" at biology news

Key heart and Alzheimer's disease protein imaged for first time in native state

...ons, according to the researchers. Details of the works are reported in the January 13 edition of the Journal of Biological Chemistry. "This is the first successful use of x-ray crystallography to reveal the structure of a protein bound to lipids," explains senior author Karl Weisgraber, PhD, a senior in...

Research could lead to better drugs and whiter whites

...stains; a better understanding of how this process works could one day lead to more effective, faster acting agents." ...

Robot assisted surgery more accurate than conventional surgery

...ients undergoing partial knee replacement. Acrobot works by helping the surgeon to line up the replacement ...sed accuracy makes a difference to how well a knee works after surgery, we will be able to develop a new generation of less invasive procedures without the r...

New antimicrobial compound adheres to skin to promote healing

...lesions on fish and other aquatic animals. Tricide works by enhancing the effectiveness of antibiotics. "In the case of burn victims, whether animal or human, bacteria and fungi can infect the open wounds and kill the patient," Ritchie said. "We have found a way to kill those drug-resistant bacteria and ...

Research updates 65-year-old genetic discovery

...st Foundation for Biomedical Research. Stone, who works on applications of population genetics to questions concerning the origins, population history and evolution of humans and the great apes, sent DNA samples of each of three subspecies of chimpanzees to the University of Utah. "No chimpanzees were ha...

Worm hormone discovery may aid fight against parasitic disease

...eam are related to how hormone-replacement therapy works in humans. For example, in patients with Addison's...ch sought-after in terms of how the DAF-12 protein works and whether it had a hormonal regulator. Mother Nature has used this system from the very simplest n...

Creation of antibiotic in test tube holds promise for better antibiotics

...ost-translational modification of proteins. Nisin works well against Gram-positive bacteria and food-borne pathogens that cause botulism and listeriosis because it punches holes into cell membranes and binds to essential molecules in the disease-causing bacteria. Hitting on at least two targets reduces th...

Scientists make first step towards 'holy grail' of crystallography

... this is the first time we have designed one which works on a large number of materials." The researchers plan to commercialise this discovery using Imperial Innovations, the College's technology transfer company. ...

Faults in newly discovered breast stem cells may lead to tumours

... explanation for such a recurrence. Chemotherapy works by targeting cells that are dividing rapidly, which is typical behaviour of cancer cells. But an errant stem-like cell may be more resistant to chemotherapy because it divides more slowly. So while chemotherapy can eliminate the bulk of cancer cells,...

Scientists identify molecular structure of key viral protein

...omplete picture of how the paramyxovirus F protein works to infect the cell. The F protein belongs to a g...uctures -- and an understanding of how the protein works -- remain incomplete. "The protein we studied," explained Lamb, an Investigator for the Howard Hugh...

One fish, two fish: New MIT sensor improves fish counts

...e in size and shape over time. The new technology works best along the continental shelf, so the researchers focused their attention on the waters south of Long Island, New York. When they first started, they weren't looking for fish at all - they wanted to see if their device could locate ancient riverbe...

Enzyme crystal structure reveals 'unexpected' genome repair functions

... of the anticancer drug cisplatin, since cisplatin works by initiating the process of DNA repair, in turn activating apoptosis or programmed cell death when the repair process fails. "Because chemotherapeutic agents like the chemotherapy drug cisplatin and radiation therapy work by essentially damaging DNA...

Newly discovered killer cell fights cancer

...laboratory. Most of the immune system typically works through a web of cross-talk and signaling among a variety of cells. One of the first immune cells that invading bacteria or cancer cells - both of which carry antigens that alert the immune system - may encounter is a natural killer (NK) cell. As i...

Radiotherapy advance points way to noninvasive brain cancer treatment

...s," she says. "But first, you want to know that it works and that it really has potential for saving lives....be a year before it is known whether the treatment works in animal models, and likely another five to ten years before clinical trials and available treatmen...

Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers

...tiated the cells look in a prostate cancer sample, works fairly well when the score is either very low or very high, but the prognosis for men who have scores in the mid-range is difficult to predict, Wang-Rodriguez said. "It is very difficult to predict relapse and cancer recurrence in men who have a sc...

AIDS-related cognitive impairment exists in two separate forms

...tiated the cells look in a prostate cancer sample, works fairly well when the score is either very low or very high, but the prognosis for men who have scores in the mid-range is difficult to predict, Wang-Rodriguez said. "It is very difficult to predict relapse and cancer recurrence in men who have a sc...

APS lecturer shows rare video of 'teacher-student' immune cell interactions in live animal

...le to recognize it. "The system, while cumbersome, works because of the amazing trafficking where they circle around and look for the presence of anything that might tickle their antigen receptor," von Andrian said. If the T cells don't recognize the antigen, they hop back in the blood stream and head for...

Value of services performed by insects tops $57 billion in US

...Invertebrate Conservation in Portland, Ore., which works to protect native insect habitats through education and research. Insects are an integral part of a complex web of interactions that helps put food on our tables and remove our wastes. Humans - and probably most life on earth - would perish without ...

Trial success for diabetic nerve therapy

...covered that injection of a novel therapeutic that works by stimulating a person's genes may prevent nerve damage ?primarily to the hands and feet ?caused by the disease. The positive preclinical results ?reported in the journal Diabetes ?are further evidence that the research could lead to a new treatmen...

Johns Hopkins lab scientists tame overactive CF protein

...lin says. "Using RNA interference, which basically works by silencing the expression of genes or proteins, we homed in on VCP and blocked its production. That let the defective CFTR to successfully sneak past the quality control and race up to the surface." To determine VCP's role in the destruction of CF...

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