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A gene's first 'kiss' sets off that affair known as puberty

...aper are Muhammad Shahab, Ph.D., formerly a fellow working with Dr. Plant and now with the department of biological sciences at Quaidi-i-Azam University in Islamabad, Pakistan; Claudio Mastronardi, Ph.D., and Sergio R. Ojeda, D.V.M., both from the division of neuroscience at the Oregon National Primate Resea...

Man and mouse share genome structures

...s a chain of beads which is then compressed into a working chromosome. Chemical tags placed on the histones a...p the analytical techniques several years earlier, working with the smaller yeast genome. To investigate the much larger human genome, they collaborated with A...

New, automated tool successfully classifies and relates proteins in unprecedented way

...ey can refine their approach further.They are also working on ways to "train" a general system that willwork for different cell types....

New Technique for Tracking Gene Regulators

...ve, and take a very long time.Scientists have been working on short cuts, but all so far have limits.For example, in one recent technique, scientists mix the regulatorprotein of interest (let’s say, CREB) with the entire genome of a celland let it bind. Then they fragment the genome into smaller pieces, 500t...

U-M scientist to talk about tissue engineering at AAAS

...roach works, Krebsbach said the next step would be working with engineers to develop anatomically correct scaffolding with the same curvature and contours of natural bones. That would help a patient develop new bone almost indistinguishable from nature's original equipment. Many researchers at University of...

Scientists seek answers on what activates deadly anthrax spores

... bacteria, as well as humans. The researchers are working with a non-pathogenic strain of anthrax. The genome sequences of four strains of the bacteria, known scientifically as Bacillus anthracis, have been determined. The group also will be exploring the three-dimensional structures and the functions of t...

Study finds more than one-third of human genome regulated by RNA

...he journal Cell, BenjaminLewis, a graduate student working jointly with Whitehead's Bartel andMIT associate professor of biology Christopher Burge, provides thefirst evidence that microRNAs influence a large percentage of life'sfunctions.The team developed a computational method to define the relationshipbet...

Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa

...ry patients are evaluated by a team of researchers working at the Eye Center and the VA Rehabilitation R&D Center including Ronald A. Schuchard, PhD and Claire Barnes, PhD. "This clinical trial will help evaluate the potential of Optobionics' ASR® device to provide improved functional vision or to at le...

The secret lives of whales

...ganic pollutants (POP’s),?says Payne, “What we are working on may be the worst public health crisis that humanity has ever faced. That’s because 70% of all humanity (4.2 billion people) depends on seafood as its primary source of animal protein, and if the fish are seriously polluted, they may soon be unsafe...

NYU researchers simulate molecular biological clock

...he journal Cell, BenjaminLewis, a graduate student working jointly with Whitehead's Bartel andMIT associate professor of biology Christopher Burge, provides thefirst evidence that microRNAs influence a large percentage of life'sfunctions.The team developed a computational method to define the relationshipbet...

Dinosaur DNA? New Patent Covers Degraded DNA recovery

...ations yet to be discovered and we look forward to working with our colleagues to thoroughly examine all the possibilities," says Dr. Ensley. Dr. Ensley is the Chairman of MatrixDesign, a biotechnology company that analyzes the genomics of human tissues and uses the information to produce high performance w...

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

...m weeks of a grueling treatment regimen that's not working and gives doctors the opportunity to switch patients early on to a therapy that may be more effective. Results of the study appear the week of March 28 in the early online edition of the Proceedings of the National Academy of Sciences. Most primary...

Scientists decipher genome of fungus that can cause life-threatening infections

...arealready proving to be invaluable to researchers working to understandand cure this infectious disease." He says the genome sequence hasenabled more rapid gene identification, fueled genome wide insertionalmutagenesis approaches, and provided the foundation for the developmentand implementation of a geneti...

Purdue proves concept of using nano-materials for drug discovery

...meters, or billionths of a meter. Researchers are working to duplicate how cell membranes function on chips in order to test the potential effectiveness of new drugs to treat diseases. Membranes, which surround cells and regulate the movement of molecules into and out of the cells, contain a variety of prot...

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

...ss. "Therefore, the migrastatin analogues must be working on something upstream of those two important steps," Dr. Huang said. Dr. HuangÕs next important step is moving these analogues into clinical trials. "We're trying right now to get a company interested in this, especially because the mice used in ou...

Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra

...he Alaska Maritime National Wildlife Refuge. While working to save the endangered Aleutian Canada goose, which the foxes were driving toward extinction, Byrd had noticed the differences between islands with and without foxes and speculated that nutrients might play a role. "He had these interesting ideas ab...

Gene Therapy For Parkinson's Disease Moves Forward In Animals

...s on for life. So we have to control it, and we're working on this as we speak. But it's not ready for clinic...n the research. “For some time Dr. Mandel has been working on the idea of introducing a vector into brain that would express GDNF. What they've found is that i...

Researchers trace evolution to relatively simple genetic changes

...during embryonic growth. Also, to be sure they're working with the correct gene, the research team used genetic engineering techniques to insert the armor-controlling gene into fish "that are normally missing their armor plates. And that puts the plates back on the sides of the fish," Kingsley said. "So, t...

Octopuses occasionally stroll around on two arms, UC Berkeley biologists report

...during embryonic growth. Also, to be sure they're working with the correct gene, the research team used genetic engineering techniques to insert the armor-controlling gene into fish "that are normally missing their armor plates. And that puts the plates back on the sides of the fish," Kingsley said. "So, t...

Studies reveal methods viruses use to sidestep immune system

...gnaling proteins," Dr. Gale said. "We're currently working to identify exactly what proteins the viral protease is attacking, which could help toward further developing the protease inhibitors and more effective therapies for hepatitis C and possibly other viral infections." A third paper, also appearing in...

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