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Tag: "within" at biology news

Weizmann Institute scientists develop a general 'control switch' for protein activity

...housands of proteins performing myriad vital tasks within cells. Since malfunctioning proteins can cause disease, the study of protein structure and function can lead to the development of drugs and treatments for numerous disorders. For example, the discovery of insulin’s role in diabetes paved the way for...

Reconstructing the biology of extinct species: A new approach

...se structures are filled with a fluid, which moves within the canals when the animal moves. The fluid's mov...cular canals and locomotor pattern is evident both within the primates alone and within the entire mammalian sample. "How an animal moves is a basic adapta...

Human genetic 'deserts' are teeming with significant life

...reviously unknown set of exons [the regions of DNA within a gene that are transcribed to messenger RNA] outside the current boundaries of the annotated genes ”, Professor Reymond will say. He and his team are among the many international collaborators working together on a pilot project to use as a ...

CU study reveals why starling females cheat

...ons. Some females mate with subordinate males from within their social group when they need help to raise their chicks. (Superb starlings are cooperative breeders, meaning breeding pairs get help in raising chicks from other family group members.) This additional male then also acquires food and tends to th...

Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state

...tics by tightly controlling how molecules can move within the nucleus. The study will be published in the Ju...p targeted therapies to stimulate adult stem cells within our own bodies to repair damaged tissues, and may provide further areas of exploration for the treat...

Gene therapy study shows safety and statistically significant improvement in Parkinson's disease

... all 12 patients were discharged from the hospital within 48 hours of the procedure. At one year, all 12 patients as a group demonstrated a clinical improvement of 25% in the Unified Parkinson’s disease Rating Scale (UPDRS) compared to baseline (p<0.005). Nine of the 12 patients showed an average of 37%...

Ancient retrovirus sheds light on modern pandemic

... to and destroys the virus before it can replicate within the body. "We know that PtERV1 infected chimps, gorillas and old-world monkeys 4 million years ago but left no traces of having infected humans. Our theory is that this is because humans had this innate viral defense system," Emerman said. To tes...

Experts predict Tamiflu could halve the pandemic influenza death toll versus no intervention

...a matched vaccine are unlikely to become available within the early months of the pandemic, making prophylaxis and treatment with antivirals a crucial part in the efforts to reduce the burden of pandemic influenza.4 “In an environment full of uncertainties, it is best to have a comprehensive plan in pla...

Modified mushrooms may yield human drugs

...alled plasmids, which have the ability to multiply within a bacterium known as Agrobacterium. The hygromycin resistance gene is a marker gene to help sort out the transgenic mushroom cells from the non-transgenic cells, Dr. Romaine explained. "What we are doing is taking a gene, as for example a dru...

Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage

...o apply for phase I human clinical trials, perhaps within 18 months, Kyrkanides said. Early results, while n... key inflammatory receptors on sensory nerve cells within the CNS. Joining Kyrkanides in the publication from the University of Rochester School of Medicin...

Treating HIV in war zones -- Public health emergencies need rapid advice from WHO

...ch a draft manuscript for publication was prepared within 10 days. In a related editorial discussing how WHO is responding to global public health threats, the PLoS Medicine editors comment that while the time scale for developing the H5N1 guideline was "miraculously quick in WHO terms", an even quicker...

Researchers use MRI to predict recovery after spinal cord injury

...f neurological recovery after SCI can be predicted within 48 hours after injury by rigorous assessment of MR...otor vehicle accidents. MRI exams were obtained within 24 to 48 hours of injury. The research team studied three measurable imaging parameters: maximum spi...

First confirmed common genetic risk factors for breast cancer

...vely small percentage of women. "Risk mutations within these genes are so rare that only a very small number of breast cancer incidences are caused by these mutations," said Jianjun Liu, Ph.D., co-author of the Nature paper and Senior Research Scientist at the Genome Institute of Singapore, one of the ov...

Extra-aggressive form of idiopathic pulmonary fibrosis identified

...ressive lung disorder from which most patients die within 5 years after diagnosis. The disease is characterized by the insidious onset of dyspnea or cough and usually evolves slowly. Now, Selman and coworkers present in an article published in the online, open-access journal PLoS ONE on Wednesday 30th ...

Want to save polar bears? Follow the ice

...bear populations depend on the decisions we making within the next year. Fortunately, by using available data on sea ice trends over the past few decades, we can make effective decisions that can make a difference for the largest carnivore on earth." The "Warm Waters for Cool Bears" initiative represents...

How brain pacemakers erase diseased messages

...op, silence' -- propagate pathological information within brain circuits," said Warren Grill, the study's lead investigator and an associate professor of biomedical engineering. "If you replace that instead with a constant 'pop-pop-pop-pop-pop-pop,' you've erased that pathological information." Grill sai...

Detecting cold, feeling pain: Study reveals why menthol feels fresh

...eer of research into the mechanism of chronic pain within the central nervous system. The Julius team's complementary work is focused at the level of the sensory nerve fiber, where the signals are first initiated. "We want to know," Julius says, "how do you detect these stimuli to begin with" How do you...

Resistant HIV quickly hides in infants' cells

...nt virus affects whether those drugs can be reused within the child’s lifetime.?This is a critical question and an area of intense investigation, especially in light of the high rates of antiretroviral drug resistance occurring in infants in low-income countries who received a single dose of an NNRTI for pr...

Mice with a migraine show signs of brain damage

...neuron’s body that usually number in the thousands within a synapse. Mice in the grasp of a migraine lost up to three-quarters of these important cellular components. Ironically, the team found that during CSD, even though blood flow in the brain overall increases dramatically, some parts of the brain st...

Does amateur boxing cause brain damage?

...ament light (NFL), was four times higher in boxers within 10 days of the fight as compared with healthy non-athletes. These increased levels returned to normal after three months rest from boxing. In addition, the increased levels after a fight were significantly higher among amateur boxers who had rece...

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