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A new mechanism of regulating RNA degradation

...aufen1 interacts with Upf1," she added. "This is a whole new function for Staufen1 that couldn't have been predicted from the studies in flies, even though a similar function may occur in flies." The team discovered that Staufen1 doesn't interact with other components of the NMD complex ?and altering the ...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

...aufen1 interacts with Upf1," she added. "This is a whole new function for Staufen1 that couldn't have been predicted from the studies in flies, even though a similar function may occur in flies." The team discovered that Staufen1 doesn't interact with other components of the NMD complex ?and altering the ...

Novel technology detects human DNA mutations

.... "Nanosphere's new SNP analysis methodology for whole genomic human DNA is a powerful example of the ver...proteomic research anddiagnostics."The analysis of whole human genomic DNA is extraordinarily complex asit requires sifting through the more than one billion...

Tiny particles could solve billion-dollar problem

...nough to provide the throughput needed to make the whole approach effective. Tests in Wong's lab have found that the gold-palladium nano-catalysts break TCE down about 100 times faster than bulk palladium catalysts. ...

Plants, animals share molecular growth mechanisms

...n," Szymanski said. "They affect the growth of the whole plant and also the shape and size of types of cell... is important and whether it regulates DIS3 or the whole WAVE complex." For growth and development biochemical processes to proceed normally, activators suc...

Scientists Replicate Hepatitis C Virus in Laboratory

...iral particles that have all the properties of the whole virus. This evidence together with an analysis of the replicated viral RNA supports a conclusion of viral replication and production.?/p> The NIDDK group used a strain of HCV that would have applications to the greatest number of people ?genotype...

Whole genome fine map of rice completed

...blished in 2002. The fine maps were assembled with whole genome shortgun approach. Through searches of 1907...the Japonica. It is reported that BGI will finish whole genome assembly and analysis for the maternal strain "PeiAi 64" (its main genetic background being J...

Finding Cures For Tropical Diseases: Is Open Source An Answer?

...Tropical Diseases: Is Open Source an Answer?" The whole article is a very good read; a summary from ScienceDaily is available in the full post. Onlyabout 1% of newly developed drugs are for tropical diseases, such asAfrican sleeping sickness and dengue fever. While patent incentiveshave driven commerc...

Genome-wide mouse study yields link to human leukemia

...ath, a process called apoptosis. "It's given us a whole new way to look at and possibly treat leukemia," says Michael Caligiuri, director of the OSU Comprehensive Cancer Center (OSUCCC) and senior co-author of the study. "It's also validated our mouse model as a good predictor of what happens in the devel...

Breakthrough Microarray-based Technology for the Study of Cancer

...zation was performed throughthe optical imaging of whole chromosomes, a technique with limitedsensitivity, ...mplification of total genomic DNA instudies of the whole genome, providing better ease of use and improvedexperimental design....

Iron Deficiency Sparks Dramatic Changes In Gene Expression

...nd abundantly inred meats, shellfish dried fruits, whole grains, spinach, seeds andother foods.Their study in yeast cells demonstrated that iron-starved cellspreserve the little iron they possess by shutting down the major ironusers in order to maintain the cell's essential functions, said DennisJ. Thiele,...

The secret lives of whales

...le hormone mimics that cause serious problems. The whole world is being feminized,?says Payne. Payne’s greatest hope is that in the next decade, the world will have taken heed, and instituted steps to reduce the entry of contaminants to the oceans. ...

Gene therapy converts dead bone graft to new, living tissue

...acing a single brick at a time without tearing the whole structure apart. Schwarz's studies with mice showed their dead splints were quickly converted to new, healthy bone. He projects that the bone would be completely converted in just a year, and that a human bone might be completely converted in as lit...

New Clues Add 40,000 Years to Age of Human Species

...lve an anthropological mystery, but it provides a whole new perspective on the history of the Turkana Basin, a setting that has provided so much important evidence regarding human evolution,?says Brown. “However, while our research pushes back our time of origin," he adds, “most cultural aspects of hum...

BRCA1 causes ovarian cancer through indirect, biochemical route

...ore facility at the USC/Norris Cancer Center. "The whole project was based on creating a mouse that lacks BRCA1 in only its granulosa cells," Dubeau says. "This collaboration was essential to the project's success." What Dubeau and his colleagues found was that while mutating the BRCA1 gene in granulosa c...

Weill Cornell Research Reveals Secrets Of Trafficking Within Cells

...nstrument," he said. Instead, they came up with a whole new method of inquiry. It combined two pre-existing technologies -- RNA interference (RNAi), where scientists cut down on protein expression by jamming the responsible gene with bits of RNA; and microscopy, which looks at the activity of individual l...

New Study from Affymetrix Laboratories Points to Changing View of How Genome Works

...isease mechanism. This project has been funded in whole or in part with Federal Funds from the National Cancer Institute, National Institutes of Health, under Contract number N01-CO-12400. About Tiling Arrays: Affymetrix "tiling" arrays mark a shift in the way microarrays are designed and interpreted. B...

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

... primary tumor cells, could someday give doctors a whole new weapon in the fight against tough-to-treat metastatic disease, according to Weill Medical College of Cornell University researchers. The compounds, called synthetic migrastatin analogues, prevented 91 to 99 percent of metastatic breast cancer ce...

ASU researchers finds novel chemistry at work to provide parrot's vibrant red colors

...ration," said McGraw. "This research is exposing a whole new world of color communication in parrots and the potential physiological and biochemical roles of the new molecules we found in our work." Details of the work are in a paper, "Distribution of unique red feather pigments in parrots," by McGraw and...

Transport System Smuggles Medicines Into Brain

...ration," said McGraw. "This research is exposing a whole new world of color communication in parrots and the potential physiological and biochemical roles of the new molecules we found in our work." Details of the work are in a paper, "Distribution of unique red feather pigments in parrots," by McGraw and...

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