A gene's first 'kiss' sets off that affair known as puberty
...r? "Puberty is critical to human development. And while there is a fairly good understanding of how the endocrine system regulates the hormones involved, just how and when the brain activates this process has been a great mystery. An appreciation of puberty's deep-seated neurobiological mechanisms could, ...Bioartificial kidney under study at MCG
...rough the cell-lined fibers of a second cartridge, while the blood is run on the outside of the fibers. "(These cells) reabsorb substances from the ultrafiltrate ?and put them back into the blood on the outside of the fiber, which is pumped back into the body. The stuff that isn't pumped out is just like ...Association of herpesvirus with lung disorder questioned
...ulmonary hypertension. The researchers noted that while their results call the earlier study results into question, there are other possible explanations for the divergent data. For example, the pathogenesis of primary pulmonary hypertension in Japan may be different from that in the United States. The se...Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
...n increase in blood cholesterol and triglycerides, while diets high in unsaturated and polyunsaturated fats...hanism actually decreased cholesterol in the liver while increasing it in the bloodstream. "Before this report, it wasn't clear what the differences were be...A new mechanism of regulating RNA degradation
...fferentially control the level of SMD-target RNAs, while leaving the NMD-regulated RNAs untouched. This is likely to be the "tip of the iceberg" for Staufen1's function in mammalian cells, said Maquat, and just the beginning of the SMD story as well. ...FDA Approves Human Hookworm Vaccine for Phase I Safety Trials
...fferentially control the level of SMD-target RNAs, while leaving the NMD-regulated RNAs untouched. This is likely to be the "tip of the iceberg" for Staufen1's function in mammalian cells, said Maquat, and just the beginning of the SMD story as well. ...Researchers discover way to make cells in the eye sensitive to light
...iction was incomplete.The researchers believe that while not a cure for blindness, thefindings could lead to therapies for treating some forms of blindness,such as retinitis pigmentosa. Retinitis pigmentosa is a form ofhereditary blindness where the rods and cones are destroyed, but therest of the eye and ...Columbia research lifts major hurdle to gene therapy for cancer
...ted prostate cancer cells in the lab and inanimals while leaving normal cells unscathed. Genetherapy based...e cancercells. All the prostrate cancer cells died while the normal cells wereunaffected.The same virus also selectively killed human cancer cells from melan...Dysentery uses 'sword and shield' to cause infection
...a which causes dysentery, is able to invade cells, while stopping any response from the immune system. The... to inject proteins into human cells, (the sword), while lipopolysaccharide (LPS) on the surface of the bacteria acts as a shield to protect the dysentery ba...Lack of enzyme turns fat cells into fat burners
...fat, highcarbohydrate diet without gaining weight, while their normalcounterparts become obese and develop type 2 diabetes."This adds another tissue or organ that helps out in the process ofenergy maintenance," said Wakil. "ACC2 is potentially a key enzyme inthe regulation of weight, obesity, and related p......-third contained no references for medical claims; while the majority of references to published material was available, only a minority of company data-on-file documents were provided upon request; and the majority of original research cited in the ads was funded by or had authors affiliated with the prod...Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
... did most of his work on the E. histolytica genome while in his previous position at Sanger. Matthew Berriman of Sanger said, "The results give a fascinating glimpse of how this ancient parasite evolved and highlight unusual metabolic processes that may be exploitable as drug targets." The project also i...Newly-discovered class of genes determines ?and restricts ?stem cell fate
...r Pan, who were able to orchestrate complex events while never growing old." Epstein thinks that this concept may also be important for understanding the cell of origin for a number of tumors. Pax3 is known to be involved in some tumors, which adds evidence to the stem-cell origin for some cancers. This t...Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
... and RNA samples were derived from lungcarcinomas, while the tissue samples were derived from multiple normaland cancerous tissues. The labs followed a common protocol for allsteps of sample preparation and microarray analysis and the resultinggene expression profiles were analyzed and compared.Sample corr...Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates
...elopment of stem cell technology but cautions that while theobservations are encouraging, the reported number of surviving DAneurons was very low, only 1?% of the cells surviving, well below theestimated number of DA neurons that survive after fetal celltransplants (approximately 10%). While this may be a ...Ecological destruction fuels emerging diseases
...now where these things are coming from." In fact, while parasites like malaria are well known, we may have identified only a fraction of the total number of the world's parasites, and the prospect of cataloguing them poses a daunting technical challenge. Since the physical characteristics of many parasite...“Nano-scissors?laser shows precise surgical capability
...f Dr. Robert Byer, a Stanford Universityprofessor, while doing post-doctoral work. The paper’s other co-authorsare Mehmet Fatih Yanik at Stanford, Hulusi Cinar, Hediye Nese Cinar andAndrew D. Chisholm at the University of California at Santa Cruz andYishi Jin of UC Santa Cruz and the Howard Hughes Medical ...Cytoplasm affects the number of vertebrae in carp-goldfish clones
...n carp have 33 to 36 vertebrae in their backbones, while goldfish have 26 to 28. Six of the seven cloned fish had between 26 and 28 vertebrae; one had 31. Although the initial rate of success in producing carp-goldfish clones is low--seven offspring in 501 attempts in this study--the authors believe that ......ranscriptional effects in a dose-dependent manner, while treating cells with the small molecule HR73, a derivative of a molecule that inhibits the yeast version of the SIRT1 protein, caused a 5-fold reduction in HIV transcription. The authors propose a cycle of transcriptional transactivation in which SIR......agues first happened upon a whale skeleton in 1987 while doing a deep-sea survey using the submersible Alvi...hale. Female sperm whales feed in tropical regions while males travel globally and feed near the poles. “For example, of the roughly one million sperm whales...