Scientists document complex genomic events leading to the birth of new genes
... of eight RGP-family genes were identified, all of which are believed to be fully functional. To demonstra...of the RGP-family isoforms. In contrast to RanBP2, which is found exclusively at the nuclear envelope, this RGP-family protein was detected in discrete cytop...Nano-Probes Allow an Inside Look at Cell Nuclei
.... First, they had to breach the nuclear membrane, which has pores that are only about 20 nanometers wide. To fit through these tiny slits, Chen and Gerion used an especially compact cadmium selenide/zinc sulfide quantum dot coated with silica. Next, they stole a trick from a virus's playbook to smuggle th...DNA Recombination and Repair—A New Twist to RecA Function
...r of DNA lesions during replication—the process by which a DNA molecule is copied to make two. RecA is als...n one ATP. This implies a filament organization in which every RecA molecule hydrolyzes ATP in synchrony with the sixth RecA molecule to its left and the six...New protein discovered by Hebrew University researchers
...tration is based onthe fact that the blood vessels which feed tumors are considerably moreporous than those reaching healthy cells. Therefore, the units of SP-1carrying the drug would invade only the tumor-feeding blood vessels andnot normal ones.More recently, the three-dimensional structure of the protei...NC State scientist finds soft tissue in T. rex bones
...urnal Science, Schweitzer describes the process by which she and her technician, Jennifer Wittmeyer, isolated soft organic tissue from the leg bone of a 68-million-year-old Tyrannosaurus rex. Schweitzer was interested in studying the microstructure and organic components of a dinosaur's bone. All bone is ...The death of a very special chimpanzee
...tration is based onthe fact that the blood vessels which feed tumors are considerably moreporous than those reaching healthy cells. Therefore, the units of SP-1carrying the drug would invade only the tumor-feeding blood vessels andnot normal ones.More recently, the three-dimensional structure of the protei...New studies suggest airborne SARS transmission is possible
... the health care setting. In the Hong Kong study, which focused on the 2003 SARS outbreak at the Prince of...al, 41 percent of patients admitted to the ward in which the first SARS patient was staying became infected. Proximity to the bed of the first case seemed to...Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation
...and attacks depends on the makeup of its receptor, which is constructed of protein building blocks. Each pr...lls have been converted to parent T cells--each of which targets a specific foreign substance, according to Rupert Handgretinger, M.D., Ph.D., director of St...Ice core 'dipstick' indicates West Antarctic ice has thinned less than believed
...is lead author of a paper describing the research, which is being published online March 23 in Geology, a j...nterpreting climate in the last ice age and since, which is key to understanding how climate is changing today, Waddington said. "To make climate judgments ...UCLA scientists transform HIV into cancer-seeking missile
.... First, the scientists used a version of HIV from which the viral pieces that cause AIDS had been removed....dressed it in the outer suit of the Sindbis virus, which normally infects insects and birds. By altering the Sindbis coat, they reprogrammed the AIDS virus, ...First real-time view of developing neurons reveals surprises, say Stanford researchers
...ea about what they'll become as adults. The work, which is detailed in a paper in the March 24 issue of Neuron, took place in the brain of a small see-through fish called a zebra fish. Stephen Smith, PhD, professor of molecular and cellular physiology, and graduate student Christopher Niell immobilized a ...New Breast Cancer Test Could Save Lives
...the number of deaths from this disease. The test, which utilises an innovative radar system, will enable w...ent - many women are dependent on self-examination which can prove unreliable. This latest technology has the ability to image through dense breast tissue, a...The Shapes Of Life: NIGMS Project Yields More Than 1,000 Protein Structures
...a to humans. Researchers can use these structures, which are determined experimentally, to build computer models of the structures of other proteins with related amino acid sequences. Although the main focus of the second phase of the PSI will be on solving protein structures, Norvell said there will be c...New insight into people who 'see' colors in letters and numbers
People with a form of synesthesia in which they see colors when viewing letters and numbers r... brain. The rare condition called synesthesia--in which people's sensory perceptual circuitry seems to be miswired--was long dismissed as an oddity not wort...Study Models Impact Of Anthrax Vaccine
...beimmunized with vaccine before an anthrax attack, which might not bepractical. However, the study found th..., and evaluated arange of vaccine characteristics, which could begin to provide immunityranging between 7 and 28 days. When vaccine was distributed along wit...The BIOS Initiative - open source biotechnology is born
...ctionalities in its highly successful Patent Lens, which includes the world's fastest free, full-text searchable patent database, with over 1.6 million patents in the life sciences. CAMBIA has flagged its intent to expand its scope beyond the life sciences to include all patents in many countries, to creat...Beyond lithium for bipolar disorder
...understanding of the still-mysterious mechanism by which lithium damps the highs and lows of the disorder. ...ers. They cited studies demonstrating that mice in which the gene is knocked out show hyperactivity and defects in their circadian (day-night) behavior--both...FDA Warns Consumers Not to Use Home-Use Diagnostic Kits Marketed by Globus Media
...ation and allows blood samples to be taken at home which people then send to a laboratory for testing. No h...le in the U.S. The FDA has issued an import alert which alerts FDA field personnel to the possible importation of the Globus Media devices, provides guidanc...New research indicates a 'troubled' greenhouse is brewing
... the cause of the late Paleocene greenhouse spike, which lasted less than half a million years, was a catas...es graced Ellesmere Island in the Canadian Arctic, which is now the treeless abode of musk oxen and polar bears." The bottom line? A new Ice Age is probably......imately 3,220 women will be enrolled in the trial, which is expected to last approximately 30 months. "Thi...hrough NIH's HIV Prevention Trials Network (HPTN), which is funded by NIAID, the National Institute of Child Health and Human Development, the National Insti...