Scientists identify genetic pathways essential to RNA interference
... that participate in the gene-silencing mechanism, which someday may help to fight human disease. The repor...tivation produced by RNAi is exquisitely specific, which gives it enormous potential for therapeutic application," says Gary Ruvkun, PhD, of the MGH Departme...A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020
...sed in this study is a“viral-vectored?approach, in which a naturally occurring virus isre-engineered to be ...rus called VEE, forVenezuelan equine encephalitis, which in its natural form can causedisease in horses.Researchers at AlphaVax, Inc., a privately held biote...Ants Genetic Engineering Leads To Species Interdependency
...y antspecies, such as the case of slavemaker ants, which have become sospecialized for raiding food from th...irtually all ant species, it is the environment in which a femaleis raised, rather than a genetic predisposition, that determines whichcaste she will adopt.H...Same mutation aided evolution in many fish species, Stanford study finds
...ic region in a large number of marine fish, all of which had a complete set of armor plates. A small number of these fish had one copy of the Eda gene that contained the mutation in question. It's likely that when a pocket of sticklebacks got isolated, at least a few of those fish already carried the muta......e History and Understanding of Medicine in London, which holds the Crick papers. The Crick collection bring...nthesis; to the deciphering of the genetic code by which hereditary information is stored and transcribed in the cell; and to our conception of the human bra...Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra
...king to save the endangered Aleutian Canada goose, which the foxes were driving toward extinction, Byrd had...ated. Ledge nesters such as murres and kittiwakes, which nest on steep cliff faces, were less affected by the foxes, he said. "Wherever the puffins and gull...Gene Therapy For Parkinson's Disease Moves Forward In Animals
...proach to this disease using in vivo gene therapy, which is very applicable to humans. It even presents the...s that produce a vital chemical known as dopamine, which carries messages that tell the body how and when to move. In tests with 31 monkeys, including a cont...Researchers trace evolution to relatively simple genetic changes
...picked one trait -- the fish's armor plating -- on which to focus intense research, using the armor as a ma...nd are, we think, in the (gene's) control regions, which turns the gene on and off on cue." So it seems that evolution of the fish is based on how the Eda ge...Scientists reveal molecular secrets of the malaria parasite
... in the mosquito. Severalgenes were identified for which transcripts were detected in the sexualstage but w...transmission-blocking vaccines" —that is, vaccines which raiseantibodies that attack the parasite in the vector. (Such antibodies arein the "blood meal" and ...Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
...picked one trait -- the fish's armor plating -- on which to focus intense research, using the armor as a ma...nd are, we think, in the (gene's) control regions, which turns the gene on and off on cue." So it seems that evolution of the fish is based on how the Eda ge...Studies reveal methods viruses use to sidestep immune system
...us genetic material. RIG-I then changes its shape, which sends a cascade of signals to other proteins to ac...on the genes responsible for producing interferon, which neutralizes viruses by suppressing their replication. The researchers also investigated why cells w...Development of portable infectious disease detector
... applications."One of the key VIIBRE capabilities, which was developed by a researchteam headed by Assistant Professor of Chemistry David Cliffel, is thedevelopment of a sensor suite capable of simultaneously measuring theconcentrations of the key chemicals that cells consume andexcrete--oxygen, glucose an...Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers
...ir we breathe is toxic to us. Indeed, fruit flies, which have been studied closely for decades, die sooner ...nitored the moth's breathing pattern. The chamber, which housed the moth being studied, was filled first with air that had been freed of carbon dioxide. Next...Scientists discover unique microbe in California's largest lake
...ence data for thesmall subunit ribosomal RNA gene, which encodes part of the cell'sprotein synthesis machinery, they demonstrated that chlorophylld-producing blue-green algae (more technically known as cyanobacteria)have acquired a piece of DNA from a proteobacterium, a distant relativethat last shared a c...Alcohol's effects on gene expression in the central nervous system
...have exactly the same deoxyribonucleic acid (DNA), which means they all have the same genes," explained Wil...brain damage. "The challenge has been to find out which genes ?out of more than 50,000 ?are turned on or off in the brains of alcoholics," he said. "Microar...Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems
...nt. The same pattern occurred for kidney disease, which was found in 74 percent of the normal male animals at the time of their deaths. None of the growth-hormone deficient animals developed kidney disease. They found that animals with a deficiency in growth hormone initiated after adolescence had up to ...Research Gives Hope For Liver Damage
...ch by theUniversities of Edinburgh and Southampton which may lead to newlife-saving treatments. There is cu..., will help doctorsto understand the mechanisms by which the liver is damaged and repairedand may lead to future treatments. Researcher Dr Jeremy Duffield e...New SARS Protein Linked To Important Cell Doorway
...y. "Now we can take these viral genetic sequences, which can be attained very rapidly, and get a head start...es in culture." Fremont led the initial analysis, which was dedicated to identifying sequences of genetic code that might translate into proteins that could...MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks
...scribes MSI's discrete stochastic event simulator, which keeps trackof the thousands of complex species for... Health's National HumanGenome Research Institute, which designated MSI as a Center ofExcellence in Genomic Research. The CEGS program supportsmulti-investig......r, Swiftwater, PA, manufactured the trial vaccine, which is an inactivated vaccine made from an H5N1 virus ... and unpredictably and involve strains of virus to which humans have little or no immunity. H5N1 is one such flu virus strain. The last influenza pandemic sw...