Elusive HIV shape change revealed; Key clue to how virus infects cells
...ct. Once it binds, gp120 undergoes a shape change, which signals a companion protein, gp41, to begin a set ... One of the lab's first steps will be to determine which shape of gp120 ?bound to the CD4 receptor, or unbound ?is recognized by a person's antibodies. gp120...Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
...ute to the organism's unique biology. The report, which appears in the February 24 issue of Nature, presen...titute of Allergy and Infectious Diseases (NIAID), which is part of the National Institutes of Health, and from the Wellcome Trust. The study's first author...Antarctic ice shelf retreats happened before
...may be causing the glaciers inland to flow faster, which could lead to enhanced drainage of part of the West Antarctic Ice Sheet, and a consequent rise in sea level. ...Anti-bacterial additive widespread in U.S. waterways
...was 28 fold higher thanpreviously reported levels, which are currently used by the U.S.Environmental Protec...n due to unfavorable environmentalcharacteristics, which include long term persistence and potentialbioaccumulation. Triclocarban, for example, has an estima...Newly-discovered class of genes determines ?and restricts ?stem cell fate
...mors. Pax3 is known to be involved in some tumors, which adds evidence to the stem-cell origin for some cancers. This theory proposes that many cancers may arise from normally scarce resident stem cells that grow uncontrollably, rather than from the vast majority of differentiated cells that make up organs...Timing is everything: First step in protein building revealed
...ene's instructions,it will make the wrong protein, which can kill the cell or lead todisease."The ribosome ...another, thefluorescent chemicals subtly interact, which changes the color orwavelength of light that is given off. If the distance between thefluorescent mo...Tiny particles could solve billion-dollar problem
...of magnitude over bulk palladium catalysts." TCE, which is commonly used as a solvent to degrease metals and electronic parts, is one of the most common and poisonous organic pollutants in U.S. groundwater. It is found at 60 percent of the contaminated waste sites on the Superfund National Priorities List...UW's Rosetta software to unlock secrets of many human proteins
...ed in less than a year.IBM's World Community Grid, which was built using grid technologydeveloped by United Devices, will enable millions of people tovolunteer their personal computers to run Rosetta during periods ofcomputer downtime.The information will be entered into a publicly accessible database,whic...Plants, animals share molecular growth mechanisms
...achine that controls formation of actin filaments, which are important for cell growth and movement. Actin ...ctivated ARP2/3, but they didn't know specifically which WAVE protein was the actual switch. Their latest research showed that a WAVE protein they've dubbed ...Researchers find how protein allows insects to detect and respond to pheromones
...ed in less than a year.IBM's World Community Grid, which was built using grid technologydeveloped by United Devices, will enable millions of people tovolunteer their personal computers to run Rosetta during periods ofcomputer downtime.The information will be entered into a publicly accessible database,whic...Researchers Uncover Key Step In Manufacture of Memory Protein
...titutes of Health. The protein is known as mBDNF, which stands for mature brain-derived neurotrophic facto... golgi apparatus. There, the proBDNF binds to CPE, which protrudes from special rafts of fatty, cholesterol-rich molecules known as lipids. If this binding p...Plants respond similarly to signals from friends, enemies
...anges in distribution of the plant's cytoskeleton, which is part of a pathway that leads to a series of gro...ither nodules housing bacteria or giant cells from which the nematodes feed. The scientists also discovered that, like rhizobia and contrary to popular beli...Scientists Replicate Hepatitis C Virus in Laboratory
...s virus and to test potential antiviral compounds, which may lead to new therapies for the liver disease th...l Institutes of Health (NIH), conducted the study, which appears in the Feb. 15, 2005 issue of Proceedings of the National Academy of Sciences (PNAS). “Unti...Research advances quest for HIV-1 vaccine
...tiative's Neutralizing Antibody Consortium (IAVI), which is focused on understanding broadly neutralizing antibodies at the molecular level and transferring this knowledge into the design of vaccines capable of stimulating broadly neutralizing antibodies against globally diverse HIV. According to Dr. Wayne...The secret to longevity in tubeworms
...gy from hydrocarbons to reduce sulfate to sulfide, which L. luymesi absorbs through its unique "roots," ext...lease sulfate back to the microbial consortia from which it draws its sulfide. Without this return of sulfate, the model predicts an average lifespan of only...Male circumcision reduces risk of HIV transmission from women to men
...ho have multiple, concurrent heterosexualpartners, which was found to be significantly higher than infectiv...the cohortsconsisted only of monogamous couples in which the female partners wereHIV-positive. However, in some areas of Africa where HIV infectionrates are ...Another Look Finds Promising Proteomics Test is Not Biologically Plausible
...rates the need for researchers to set standards by which to conduct proteomics research,?meaning that proto...ith the experimental ovarian cancer test at issue, which was first proposed in 2002 by researchers in the journal, Lancet. That study reported dramatic resul......rates the need for researchers to set standards by which to conduct proteomics research,?meaning that proto...ith the experimental ovarian cancer test at issue, which was first proposed in 2002 by researchers in the journal, Lancet. That study reported dramatic resul...Cracking the olfactory code in bees
...rates the need for researchers to set standards by which to conduct proteomics research,?meaning that proto...ith the experimental ovarian cancer test at issue, which was first proposed in 2002 by researchers in the journal, Lancet. That study reported dramatic resul......rates the need for researchers to set standards by which to conduct proteomics research,?meaning that proto...ith the experimental ovarian cancer test at issue, which was first proposed in 2002 by researchers in the journal, Lancet. That study reported dramatic resul...