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Tag: "which" at biology news

Breast Cancer May Be 'Uniquely Sensitive' To Inhibitors Of PI3K Pathway

...Department of Molecular Therapeutics. Thispathway, which is linked to critical growth factor receptors and isinvolved in programmed cell death, is aberrant at multiple levels inbreast cancer, including mutations in PI3K itself or its many“downstream?players, such as PTEN, or AKT.“There is a lot of crosstal...

Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimer's, Parkinson's Disease

...e interactions by retracting the tip of their AFM, which can measure changes in force at the atomic scale. Pulling back the tip can induce a measurable tug on the chemical bonds that hold together the two elevated monomers. By pulling on such bonds, the Duke scientists can deduce how much energy was requi...

Genetic Variation Visualization - From EMBL

...Department of Molecular Therapeutics. Thispathway, which is linked to critical growth factor receptors and isinvolved in programmed cell death, is aberrant at multiple levels inbreast cancer, including mutations in PI3K itself or its many“downstream?players, such as PTEN, or AKT.“There is a lot of crosstal...

MetaChip provides quick, efficient toxicity screening of potential drugs

...imately 3,220 women will be enrolled in the trial, which is expected to last approximately 30 months. "Thi...hrough NIH's HIV Prevention Trials Network (HPTN), which is funded by NIAID, the National Institute of Child Health and Human Development, the National Insti...

Newly Discovered Compound Blocks Known Cancer-Causing Protein

...e from the Duke Small Molecule Screening Facility, which houses a library of more than 13,000 compounds available for screening promising drugs with potential to fight cancer and other diseases. Using automated robotics, the facility provides the kind of drug discovery capability usually available only to ...

New Mixing Method for Microchip-Sized Labs

...Department of Molecular Therapeutics. Thispathway, which is linked to critical growth factor receptors and isinvolved in programmed cell death, is aberrant at multiple levels inbreast cancer, including mutations in PI3K itself or its many“downstream?players, such as PTEN, or AKT.“There is a lot of crosstal...

Simple drug has the potential to save many lives threatened by malaria

...ide hospital, so buying time by starting treatment which is easy to administer in the community is crucial. Researchers in Uganda compared the effectiveness and safety of conventional treatment (intravenous quinine) with an alternative treatment (artemether, given as a suppository) in 103 children aged be...

Tiny scaffolding allows stem cells to become working fat cells

... or Dacron, fibers that served as scaffolding upon which new fat cells were grown. In conventional cell cu...or up to a year. "We know that the environment in which a community of cells finds itself has a great deal of influence on the biology underway within those...

Plants defy Mendel's inheritance laws, may prompt textbook changes

...collaborator Susan Lolle found that Arabidopsis in which each parent plant had two copies of a mutant gene ... a cluster. "If you take this mutant Arabidopsis, which has two copies of the altered gene, let it seed and then plant the seeds, 90 percent of the offsprin...

UCSD discovery may help extend life of natural pesticide

...he design and use of Bt toxins to prevent insects, which the researchers believe also possess the molecule,...al Science, details the structure of a molecule to which Bt attaches, or "binds," in the lining of the intestines of insects and roundworms. The molecule is ...

Scientists identify new model Of NK cell development

...where they learn their role. In contrast, B cells, which make antibodies, remain and mature in the bone marrow. Until now, scientists thought NK cells did the same. But Caligiuri, working with Aharon Freud, the lead author of the study and a doctoral candidate in Caligiuri's laboratory, had noted other wo...

The very unexpected life and death of a leukemic cell

...phocytic leukemia (CLL) is an incurable disease in which cells in the bone marrow grow and survive to the p...veal that a correlation exists between the rate at which CLL cells are born and the clinical activity or progression of the disease in a patient. The disease...

Study of genomic DNA leads to new advances in cancer diagnostics

...ure diagnostic applications. The cell smear assay, which is similar to methods commonly used in diagnostics...r by disrupting any of three cytoskeletal systems, which link the outside of the cell to the genome. Using this information, Dr. Maniotis's group developed a...

New RNA polymerase discovered in plants

...n alternative form of either Polymerase I (Pol I), which makes the largest of the ribosomal RNAs, Pol II which makes RNAs for protein-coding genes, or Pol III, a specialist in making the shortest of the ribosoma...

NJIT Presidential Award winner takes stem cell research another step

...She is performing tests on diabetic animals, after which she'll test patients at the clinical level. Arinz... the current treatment for repairing bone defects, which is the use of allograft tissue, as well as newer treatments such as combining allograft with stem ce...

Bird Brains Show How Trial and Error May Contribute to Learning

...knows only one scratchy tune learned in its youth, which it performs repeatedly and intensely when females are listening. But occasionally, the finch might improvise, experimenting with a slower, more sultry variation or emphasizing different notes. Neurobiologists studying the finch now say the improvisa...

New methods of gene delivery using lasers

...nes to cells using laser light. The new technique, which is cheap and powerful, could have important implic...ngineering and Physical Sciences Research Council) which aims to use light to enhance our understanding of biology and to develop new biomedical devices. Alt...

Breakthrough method in nanoparticle synthesis paves the way for new pharmaceutical and biomedical applications

... control the size and morphology of nanoparticles, which can be used in pharmaceutical synthesis and novel ...icles lies in the production of pure chiral drugs, which make up over one-third of all pharmaceutical drugs currently sold worldwide. Chiral drugs are compri...

Boosting HIV screening can increase survival and is cost effective

..." said Paltiel. "It has a long asymptomatic phase, which can be diagnosed using very effective, inexpensive...'s Hospital in Toronto, led another study in NEJM, which strongly supports Paltiel's findings. They developed a computer model to estimate the health benefit...

RNA project to create language for scientists worldwide

...ontis will serve as coordinator of the consortium, which includes scientists from the United States, Great ...structural bioinformatics--the field of science in which biology, computer science and information technology merge. Methods he has developed for analyzing a...

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