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Tag: "when" at biology news

An HIV Protein Plays a Surprising Role in Gene Activation

Retroviruses are expert manipulators when it comes to co-opting their host's cellular resources. A great deal of human complexity stems from the vast repertoire of proteins and mechanisms dedicated to the business of regulating gene expression, and retroviruses like HIV have evolved myriad w...

Mouse brain tumors mimic those in human genetic disorder

...ong the optic pathway began multiplyingand growing when the animals were around three weeks old, developinginto optic pathway gliomas by two months of age. After thattime-period, which is roughly equivalent to teenage years in humans,the cells slowed down to the same growth speed as astrocytes in controlm...

New Clues Add 40,000 Years to Age of Human Species

...Modern humans were not a priority at the time, and when members of the Kenyan team found Omo I and Omo II,...ted on the African continent, but they differed on when modern humans first evolved, how humans dispersed to populate the globe, and what happened when, or ...

Spider Venom Could Yield Eco-Friendly Insecticides

...er "cooperates" by rearing up in a fighting stance when provoked, making it relatively easy for researchers to aspirate venom directly from its fangs. Since Australian funnel-web spiders can live for more than five years in captivity, a small group of these spiders yields plenty of toxins for King's chemi...

Gene variations explain drug dose required to control seizures

...ysicians must rely on a one-size-fits-all approach when making decisions about which drug to use and in what dose," Goldstein said. "This study makes clear that such an approach is not sufficient. People with epilepsy are genetically different from one another, and some of those differences affect their r...

Enzyme shown to help protect genomic stability

...n, the substructure of chromosomes. In many cases, when the DNA is tightly wrapped around the histones, the genes cannot be accessed and their expression is repressed. When the coils of DNA around the histones are loosened or the histone molecules are altered, the genes become available for expression. I...

BRCA1 causes ovarian cancer through indirect, biochemical route

... tumors did not arise in granulosa cells. Instead, when the tumor cells were analyzed, they were found to be epithelial cells very similar to those found in human ovarian cancers, with perfectly intact, functioning copies of the BRCA1 gene. "What this says is that the cells that control the menstrual cyc...

Scientists decipher genome of fungus that can cause life-threatening infections

...gle-nucleotide) DNA differences and differences in when the genesare expressed (turned on or off) ?may account for the disparity invirulence.Among the surprising findings of the study were the complex genestructures discovered in C. neoformans that are unlike those found inpreviously sequenced yeasts and ...

Needling Chromosomes Reveals Cell Division Secret

... was based on biochemicalexperiments that revealed when the "glue" protein called cohesin thatholds chroma...till attached. Paliulis was a Duke graduatestudent when she performed the experiments, but is now a postdoctoralfellow at the University of North Carolina a...

Poplar trees redirect resources in response to simulated attack

...ant (red is high; blue is low). Panel B shows that when that same plant is retested after exposure to jasmonic acid, a potent plant hormone that makes the plant 'think' it's under attack, it partitions more of its carbohydrates to the roots for storage. ...

Purdue proves concept of using nano-materials for drug discovery

... devices with an enzyme that produces a blue color when combined with a liquid that contains molecules small enough to easily pass through the pores. The enzyme, which is a protein, was placed inside the vessels - on the inner surface of the alumina membranes - and the liquid was placed outside each vesse...

Scientists discover the cellular roots of graying hair

...th anestimated 7,910 deaths. Melanoma can be cured when it is detected andtreated early, but if the lesion...follicleis signaling the stem cells that is absent when aging occurs and thestem cells die off? Now we have a much more refined way of dissectingthat signal...

Researchers identify target for cancer drugs

...ash on Akt and thus suppresses cell division. But when PTEN is mutated and unable to function, Akt breaks...abatini. The exact means by which Akt switches on when it reaches the cell membrane has only been partially understood. As a result, researchers have lacke...

Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery

...th anestimated 7,910 deaths. Melanoma can be cured when it is detected andtreated early, but if the lesion...follicleis signaling the stem cells that is absent when aging occurs and thestem cells die off? Now we have a much more refined way of dissectingthat signal...

Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.

...th anestimated 7,910 deaths. Melanoma can be cured when it is detected andtreated early, but if the lesion...follicleis signaling the stem cells that is absent when aging occurs and thestem cells die off? Now we have a much more refined way of dissectingthat signal...

Experiments provide proof of how traveling in groups protects insects

...ew events involving animals are more dramatic than when they band together and head out on the march cross...vidual crickets and find out what happened to them when they were in the band and also when we removed them and put them in other locations by themselves," ...

Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease

... How nature wraps and tags genes determines if and when they become active, according to researchers from ...otes. "Some of the genes can cause cancer directly when altered by mutations." "The work we're doing now is very fundamental," he says. "But what we learn ...

New research questions basic tenet of neuron function

... that sequester neurotransmitters and release them when needed into the synapse, or space between nerve ce...ir neurotransmitters in two different "modes" ?one when the neuron is stimulated and actively relaying a message, and the other through spontaneous release ...

Weill Cornell Research Reveals Secrets Of Trafficking Within Cells

...s into the kinds of disease states that can happen when clathrin-regulated endocytosis goes wrong. The fi... deeper, and discover what happened to endocytosis when amounts of clathrin increased gradually. "The knock-out mouse model was just too blunt an instrument...

Experiments provide proof of how traveling in groups protects insects

...ew events involving animals are more dramatic than when they band together and head out on the march cross...vidual crickets and find out what happened to them when they were in the band and also when we removed them and put them in other locations by themselves," ...

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