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Prenatal Stress Keeps Infants, Toddlers up at Night, Study Says

...sessed pregnant women living in Avon, England, who were due to give birth in a 21-month window. More than ...onnaires that gauged how depressed or anxious they were at multiple points early on in, late in, and after their pregnancy. Later on, the women were then as...

St. Jude study solves mystery of mammalian ears

...han 100 times better than it would be if the cells were absent. As sound waves race into the inner ear at hundreds of miles per hour, their energy—although dissipated by the cochlear fluid—generates waves in the fluid, somewhat like the tiny waves made by a pebble thrown into a pond. This energy causes t...

Genomic Analysis Uncovers New Targets for HIV Vaccine

...ry goal of CHAVI." Two of the polymorphisms found were in genes controlling the human leukocyte antigen (...technology used and collaborative efforts involved were truly remarkable: together as a group we were able to do something that none of us individually coul...

Scratch no more: Gene for itch sensation discovered

...Chen's team became interested in GRPR because they were looking for genes in the pain pathway. Among poten...o the brain. So they began to study some mice that were missing the GRPR gene to find out how they were different from normal mice. "The research was a lit...

One species, many genomes

...k Institute for Developmental Biology. The results were surprising: The extent of the genetic differences ...strates Weigel the extent of the project. The data were evaluated with several specially designed statistical methods, including a variant of machine learni...

Common cancer gene sends death order to tiny killer

...ng this killed cells that contained p53, but fewer were killed in cells lacking p53, further suggesting that this microRNA gets its kill orders from p53. When researchers examined pancreatic cancer cells known to contain damaged or missing p53, they found that those cells had limited or zero miR-34a. ...

Research identifies protein that signals flowering in squash plants

...ignal in this system. Next, heterografting studies were conducted using flowering Cucurbita maxima (pumpkin) stocks (the stock is the portion below the graft union containing the roots) grafted to non-induced, LD-grown C. moschata scions (the portion above the graft union). These experiments led to flower...

Agent slows aging in mice

...Laboratory in Bar Harbor, Maine. The scientists were surprised to find so quickly that one agent showed promise: NDGA, a compound derived from creosote bushes. These common North American desert shrubs have been traditionally used by Native Americans as healing remedies. The preliminary results, t...

Enzyme delivered in smaller package protects cells from radiation damage

...ansfected with MnSOD. After irradiation, the cells were plated in a growth medium and incubated at body te...ys at which time colonies of greater than 50 cells were counted. The MnSOD transfected cells were significantly more resistant to ionizing radiation tha...

Cells re-energize to come back from the brink of death

... conducted in culture dishes in which normal cells were exposed to cancer drugs or other agents that triggered apoptosis. The researchers then blocked apoptosis in order to study CICD. “The GAPDH response appears to represent a basic, reproducible event. But in order to verify that hypothesis, we’ll need ...

Brain inflammation may be friend, not foe, for Alzheimer's patients

...th, watching for effects in the brain regions that were awash in higher-than-normal levels of IL-1beta. It’s the first use of an organism where scientists can boost IL-1beta in select areas and then watch what happens as the process unfolds. The team expected to see the telltale clumps of material know...

Blood test may help signal tumor's remission, return in throat cancer patients

...ins following chemotherapy and radiation treatment were more likely to remain in remission, while those wh...ctors dropped and remained low following treatment were more likely to continue in remission. Patients who experienced large increases in protein levels wer...

Releasing fish for the future

... Some guidelines designed to improve fish survival were recently developed for released line-caught snappe...eting. Dr Broadhurst said some of these actions were found to massively boost fish survival. “Simply cutting the line rather than attempting to remo...

Liver cancer patients with high serum levels of hepatitis B virus face poorer outcomes

...had sera available to determine HBV DNA levels and were included in the study. For each patient, the re...al. Other factors significantly affecting survival were high total bilirubin and HCV infection. “The present study has shown that a pre-chemotherapy vira...

Soils offer new hope as carbon sink

... the same when applications of nitrogen fertiliser were added to both the agrichar and the control plots. "For the wheat, agrichar alone was about as beneficial for yields as using nitrogen fertiliser only. "And that is without considering the other benefits of agrichar." Regarding soil chemistry, ...

Math that powers spam filters used to understand how brain learns to move our muscles

...rm memory was periodically purged, repeated errors were transferred to a long term memory bank. The co... “looking” at a spot of light. Then all the lights were turned off. The spot of light was turned on again and the computer learner was again asked to look a...

Cigarette smoke alters DNA in sperm, genetic damage could pass to offspring

...es not contain any known genes. The “smoking” mice were exposed to two cigarettes per day, the equivalent ...t the rate of Ms6-hm mutations in the smoking mice were 1.4 times higher than that of non-smoking mice at six weeks, and 1.7 times that of non-smoking mice ...

Old memory traces in brain may trigger chronic pain

...g. The brain seems to remember the injury as if it were fresh and can’t forget it. With new...hamber –- one side light, one dark. When the rats were in their preferred dark side, scientists mechanically stimulated their sensitive limbs. The rats did...

Gene therapy delivery of nerve growth factors reverses erectile dysfunction in animal model

Rats with erectile dysfunction, or ED, that were injected with a gene therapy vector containing either of two nerve growth factors were able to regain normal function after four weeks, according to a study conducted by University of Pit...

Researchers track how spores break out of dormant state

...at triggers germination, nanometer sized etch pits were seen developing in the rodlet layer. These etch pits evolved into ever widening fissures, leaving narrow strips of remaining rodlet structure. In the end, 1- to 3- nm-wide fibrils remained. The in vitro AFM imaging also revealed the porous fibrous ce...

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