New path from estrogen to survival in breast cancer cells described
...reast cancers. Researchers are interested in ways that cells can efficiently turn genes on or off, and one of the newest mechanisms is dubbed "NEDDylation," which Yeh helped to find 10 years ago. This process requires multiple enzymes to attach NEDD8 to other proteins. To find proteins that can ...How does a zebrafish grow a new tail?
...it regeneration in mammals and man. So, if we find ways of interfering with the function of Wnt5b, we might be able to promote regeneration." Moon added that, because the same genes for turning on and turning off growth and development are found in humans, and drugs exist that can regulate this pathway,...UGA scientists unravel 'molecular inch-worm' structure of walking-pneumonia bacterium
...e disease works gives us a new edge in thinking of ways to overcome such infections." ...How many genes does it take to learn? Lessons from sea slugs
...f learning and its brain cells communicate in many ways identical to human neural communication. In the new findings, scientists identified more than 175,000 gene tags useful for understanding brain functions, increasing by more than 100 times the amount of genomic information available for study, acco...Pure carbon nanotubes pass first in vivo test
...ting his own battle with cancer and developing new ways to treat the disease that ultimately took his life. These new results are simply the first fruits of his final contributions in nanohealth research, and there are still more to come." ...Save the whales? Sure, but how many?
...currently used to set PTLs, and showed the diverse ways in which they apply to national laws and international treaties. According to the paper's author, WCS ecologist Dr. Eric Sanderson, 'minimum viable populations' ?the goal commonly used by wildlife managers that aims to have self-sustaining populati...Scientists work to identify genes that contribute to early heart attack risk
...ter study began in 2000 and is working to find new ways to detect heart disease before any symptoms occur. The MESA study examined about 6,800 men and women, ages 45 to 84, who had no known heart disease. These participants were screened for atherosclerosis using non-invasive imaging tests. There are si...Trotting with emus to walk with dinosaurs
...ple-sized and their steps and strides were in many ways similar to those that people might make," he remarked. What emus revealed, says Breithaupt, is that many mysterious dinosaur tracks became quite easily understood when a live animal was seen in action. Breithaupt will be presenting some of hi...Immune cell communication key to hunting viruses, Jefferson immunologists show
...s, says Dr. Sykulev, is critical to finding better ways to manipulate it and could have implications for improved vaccine development. To better understand how proteins are recognized by killer T-cells, Dr. Sykulev and his co-workers created a biosensor out of semiconductor nanoparticles called quantum do...Fire ant-attacking fly spreading rapidly in Texas
... kinds, coming after worker ants in many different ways at once," says Gilbert. "Different phorids specialize on small or large workers, on distinct chemicals laid down by the ants on trails, on time of day and on season and so forth. Our goal is to copy what we believe to be nature's complex control syst...Striking the right balance between excitation and inhibition
..., we can now look and see if it is used in similar ways elsewhere to make different kinds of neurons." The neurons in the dorsal spinal cord analyzed by the Goulding lab form a relay station receiving and interpreting sensory signals from the environment and then sending them to the brain. In doing so th...Looking to a new era in bee research
...ions to an all floral diet. Several papers address ways that honey bee studies can provide insights into human health. These papers cover the genetic bases of honey bee venom allergens, along with mechanistic insights into the remarkable longevity of queen honey bees and sperm stored in the spermatheca. ...Targeted virus compels cancer cells to eat themselves
...owing up the malignant glioma findings by studying ways to improve the efficiency of viral infection of cancer cells. ...Master planners in brain may coordinate other areas' roles in cognitive tasks
...y to take one stimulus and process it in different ways to produce different feedback. Different parts of ...ecialized abilities that can contribute in various ways to completion of different tasks. They just have to be lined up to play their part when their abilit......ections. Consequently, researchers are looking for ways to expand HSCs prior to transplantation. HOXB4 is known to be involved in stem cell maintenance and had shown some promise for stem cell expansion in mice. To investigate the potential of HOXB4 treatment for HSC expansion before transplantation in hu...Inheriting a tendency to brain infection
... individual's genetic makeup contributes in subtle ways to susceptibility to infectious disease, new findi...une system should make it possible to devise novel ways to make it succeed," he said. Since the mid-1950s, most infectious disease researchers have belie...UWM brain research supports drug development from jellyfish protein
...buting to neurodegenerative diseases. "There are ways in which cells control the influx of calcium, such as sequestering it by binding it with certain proteins," said Moyer. "If it weren't for these proteins, the high level of calcium would overwhelm the neuron and trigger a cascade of events ultimately...Genetic 'roadmap' charts links between drugs and human disease
...ions of novel therapeutic compounds and to suggest ways that existing drugs can be newly applied to treat diseases such as cancer. Based on the results, the papers propose a public project to expand this initial human Connectivity Map -- in the spirit of the Human Genome Project -- to accelerate the searc...MIT engineers probe spiders' polymer art
...-Newtonian fluids behave in strange and unexpected ways because their viscosity, or consistency, changes with both the rate and the total amount of strain applied to them. Spider silk is a protein solution that undergoes pronounced changes as part of the spinning process. Egg whites, another non-Newton...Mayo Clinic Cancer Center: Harnessing the measles virus to attack cancer
...measles to kill cancer. "We are looking at better ways to treat some of the most lethal cancers," says Ev...iple myeloma. The researchers also are looking at ways to use the measles virus to combat breast and pancreatic cancer. ...