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Herpes infection may be symbiotic, help beat back some bacteria

...essed that they did not want to minimize or in any way disregard the human suffering and health risks caused by disease-causing herpes infections. But they noted that several strains of herpes viruses found in much of the human population remain symptom-free throughout the host's lifetime. "Our results...

First demonstration of new hair follicle generation in an animal model

...or other proteins that allow the skin to heal in a way that has less scarring and includes all the normal structures of the skin, such as hair follicles and oil glands, rather than just a scar,?explains Cotsarelis. By introducing more wnt proteins to the wound, the researchers found that they could ta...

Cow protein aids in treatment of gastrointestinal disorder

... risk of resistance. “Various studies are under way to evaluate new antibiotics and different therapeutic methods to increase the efficacy of H. pylori therapy,?says lead author Nicola de Bortoli, M.D., Ph.D., adding that “data suggest that antibiotic resistance is frequent and clinicians are realizin...

Genome of yellow fever/dengue fever mosquito sequenced

.... "By introducing TEs in a more or less random way to see what happens to the laboratory mosquitoes, the TEs become a tool to study the genetic mechanism of mosquito-virus interaction, to help us understand mosquito biology and reveal new ways to interfere with disease transmission," Tu said. Acco...

Latent memory of cells comes to life

...ould simulate the experimental results and in this way gained insight into the mechanisms by which living cells with identical DNA can achieve extreme differentiation. The research at the ‘Models of Life?Basic Research Center at the Niels Bohr Institute has shown that communication between nucleosomes...

Growing nerve cells in 3-D dramatically affects gene expression

... science and engineering at Brown, wants to find a way to repair damaged nerve tissue. To get there, she needs to grow nerve cells that will flourish when placed inside the body. So Hoffman-Kim put 2-D and 3-D cell culture methods to a comparative test. Would the cells be different" Which ones would grow...

No magic tomato? Study breaks link between lycopene and prostate cancer prevention

...copene might have offered a simple and inexpensive way to lower prostate cancer risk for men concerned about this common disease," said Ulrike Peters, Ph.D., M.P.H., of the Fred Hutchinson Cancer Research Center. "Unfortunately, this easy answer just does not work." Previous studies suggested that a ...

Newly identified mechanism for silencing genes points to possible anti-cancer strategies

...production, may be operating in a completely novel way to prevent genes from producing proteins. MicroRNA...ar and senior author on the new study. "That’s one way we know that microRNAs can silence genes. That mechanism requires extraordinary specificity, however...

Intelligent materials to regenerate bone tissue

...at can put the bone right and regenerate in such a way that it carries out similar functions as in its natural state. From Spain the Institute of Biomechanics of Valencia and Progénika Biopharma S.A. are also participating. In the case of substantial deterioration of the bone, it may be necessary for ...

Switching genes to overdrive improves muscular dystrophy symptoms in mice

...The authors caution that they have not yet found a way to tweak the switch, known as PGC-1alpha, in humans. “I think that if we could elevate the levels of PGC-1alpha in the muscles of patients with Duchenne muscular dystrophy, it is likely that we could slow or reduce the course of the disease,?said ...

Biodegradable microspheres deliver time release vaccines, stimulate different immune response

...agues initially began their research looking for a way to eliminate the need for booster vaccinations, by developing a vaccine delivery system that released the vaccine into the system slowly over time. They chose a biodegradable polymer, called polyandydride, in a microsphere formulation. This polymer...

Discovery of 'master switch' for the communication process between chloroplast and nuclei of plants

...e marginal water, or marginal soil, and do so in a way that the plant won’t completely suppress its normal metabolisms and activate all of its stress metabolisms when faced with a lot of stress. If you want to generate a plant that is more tolerant, you need to deal with these two things." Added Kousse...

Uniform language for describing genes of pathogenic and beneficial microbes

... remarked: “The GO Consortium has been set up in a way that allows all users to actively contribute to th...s a tremendous open-source resource and a powerful way to advance our understanding of host-pathogen relationships.? Michelle Gwinn-Giglio, Staff Scienti...

Deconstructing brain wiring, one neuron at a time

...o do this for a very long time and finally found a way to make it possible," says the study's senior auth...onic chip works by looking down at it; there is no way to figure out how things are connected," Callaway says. "If you were given a wiring diagram, you cou...

MIT's ocean model captures diversity of underwater forests

...he oxygen we breathe on Earth. And it does so in a way that is consistent with the way real-world ecosystems evolve according to the principles of natural selection. Scientists use mo...

Researchers wake up viruses inside tumors to image and then destroy cancers

Researchers have found a way to activate Epstein-Barr viruses inside tumors as a way to identify patients whose infection can then be manipulated to destroy their tumors. They say this ...

It's never too late to get it back! Aging interrupted

...ut the low calorie diet. The problem is to find a way to rapidly identify these drugs. Professor Spindler and his colleagues are examining the gene expression patterns which are induced by low calorie diets, and looking for drugs which mimic these changes. They are searching for drugs which will have ...

Genome sequencing reveals key to viable ethanol production

... ethanol, as is currently done, Wu is working on a way to make a bacterium break down and ferment plant biomass efficiently in just one step. Wu investigated C. thermocellum, which is a microorganism that has that ability to turn biomass into ethanol in one step, but is not used at the industrial scale...

Scientists see DNA get 'sunburned' for the first time

...ways moving, he explained. It bends and twists one way or another because it is a relatively flexible mol...r two thymine bases are lined up in just the right way to bond when the UV hits, or they're not. "This insight explains why some pairs of thymine bases ...

Bones in motion: Brown scientists to create new 3-D X-ray system

...n orthopedic surgeon trying to figure out the best way to repair a torn knee ligament or an evolutionary biologist tracing the disappearance of digits in pigs would face a difficult task. To see the exact position and movement of bones and the ligaments, tendons and cartilage that surround them, would re...

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