Experimental drug reverses key cognitive deficits, pathology in Alzheimer's
...riggering initiates such cellular responses as the wave of electrical excitation of a nerve impulse. As an animal model of AD, the researchers used a "triple knockout" mouse in which three key genes involved in normal brain protein processing pathways had been knocked out, creating both amyloid plaques ...Mayo Clinic researchers discover cancer cells may move via wave stimulation
...ral understanding of how specific processes in the wave may affect such things as cell growth, cell moveme...f the cell was a previously unknown mechanism. The wave pathway appears to be a parallel pathway vital for transmitting and regulating normal cellular commu...Elephants, large mammals recover from poaching in Africa's oldest national park
...est density of large mammals in the world before a wave of unrest and poaching descended upon the region. Since the 1960s, the park's populations of elephants, hippos, and buffalos have declined dramatically, with the heaviest levels of poaching occurring in 1980s and during the past 10 years since the be...Giant deep-sea tubeworm's meal ticket comes in as a skin infection
...her infectionappears to be prevented, in part by a wave ofprogrammed cell death in tissues wherestraggling bacteria remain. "Biologists are realizing that symbiosis isnot an oddity in nature, but rather thenorm," Fisher says. "Most -- if not all --animals and plants exist in symbiosis withsome forms of m...Polynesia explorers created worldwide web of scientific knowledge
...s Rousseau as their intellectual guide. The first wave of travelers expected to find the same "natural" societies in Polynesia that had been discovered earlier in the Americas and "became the stuff of European stereotypes," Liebersohn said. What they encountered, however, "defied their expectations": sop...Corals switch skeleton material as seawater changes
...s also serve a more practical purpose: They absorb wave energy generated by hurricanes and other severe tropical storms. "Ironically, the same factor that is likely causing such storms to increase in intensity ?global warming ?is also causing the corals to bleach (lose their symbiotic algae) and die, ult...Control measures fail to stop spread of new H5N1 virus
...and Thailand, resulting in a new bird flu outbreak wave in Southeast Asia that has caused human infections as well, according to the Hong Kong/St. Jude team. The investigators also warned that it is possible that this new H5N1 variant will spread further through Asia and into Europe, as it evolves to ...When nerve cells can't make contact
...fected patients. Bourgeron' TM s work sent a shock wave through neuro-scientific institutes worldwide, as the a NLGN genes were not unknown. They are responsible for the creation of two proteins, neuroligin-3 and neuroligin-4, which are considered to play an important part in the structure of nerve cell c...Stormy days ahead for coral reefs
...assess the vulnerability of their reefs to extreme wave events," says Dr. Madin. "The ability to estimate ...rrow stalk, making them more susceptible to strong wave forces than bushy or mounded corals. Vulnerability also depends on whether the coral grows on the fr...Steep oxygen decline halted first land colonization by Earth's sea creatures
...olonization of the land," Ward said. "In the first wave the animals' lungs couldn't have been very good and when the oxygen level dropped it had to be hard for the vertebrates coming out of the water. I wonder if there is a minimum level of oxygen that has to be reached or nothing could ever have gotten o...Five new technologies that promise to transform medicine
...well-known. Other emerging technologies include wave technology to isolate cancer cells, fabrication technology to manufacture customised body parts, and the use of miniature robots to track and destroy infections before they cause disease. The individual and collective impact of these technologies ...Coral reefs are increasingly vulnerable to angry oceans
...assess the vulnerability of their reefs to extreme wave events," said Madin. "The ability to estimate the ...rrow stalk, making them more susceptible to strong wave forces than bushy or mounded corals. Vulnerability also depends on whether the coral grows on the fr...Reading Shakespeare has dramatic effect on human brain
...t registers what we call a N400 effect ?a negative wave modulation. When the brain reads a grammatically incorrect sentence it registers a P600 effect ?an effect which continues to last after the word that triggered it was first read." Researchers also found that when participants read the word produ...Study: Living coral reefs provide better protection from tsunami waves
... coast beyond. And the overarching element was the wave itself and its interaction with all these obstacle...even ocean floor, because uneven ones can funnel a wave into a certain area." Despite the limitations of the model, Oppenheimer said it provides a sound b...PNAS study reveals why organs fail following massive trauma
...NAS study offers new evidence that an overwhelming wave of biochemical signals created by the innate response after massive trauma can mistakenly trigger anergy and apoptosis, especially in T cell lymphocytes, shutting down the adaptive response before it can begin. Without the normal transition, the inna...Brain regions do not communicate efficiently in adults with autism
... the rest of autistic brain showed up on the alpha wave band. These findings support several other studies using functional magnetic resonance imaging and positron emission tomography, both of which gauge brain activity by measuring blood flow. Post-mortem studies also suggest impairments in communicati...New tool helps blood specialists improve patient care
...IM) announce the development of the first in a new wave of performance evaluation tools for blood specialists. In response to a change in requirements to maintain ABIM certification, ASH and ABIM have co-developed the Hematology Practice Improvement Module (PIM), a web-based tool physicians use to comp...Pattern of human Ebola outbreaks linked to wildlife and climate
...others have suggested that Ebola has spread like a wave surging over the Central African landscape," said ... the way the virus spreads, but it is not simply a wave affecting everything in its path, since apparently healthy mammal communities thrived in close proxi...Ebola-outbreak kills 5000 gorillas
...re recent studies showing that the Ebola infection wave is spreading rapidly towards several of the remain... The consistent spread rate of the Ebola infection wave also suggests that vaccination could be targeted just ahead of the advancing wave. The current la...Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration
...d the same as restoring vision in humans. The next wave of research will focus on characterizing the mechanisms that generate photoreceptor precursors from stem cells. Swaroop believes the research has potential for developing therapies for people with retinal and macular degenerative diseases that are u...