New tool reveals secrets of migrating cells
...up and basically do biochemistry in test tubes, or watch their behavior in a single layer of cells. It's an imaging revolution to be able to go into the native environment while keeping the intact organ alive and make movies of migrating cells." With two-photon imaging, Witt and Robey identified thymus ce...Confirmation of human protein interaction data by human expression data
...us video cameras on the fish’s developing brain to watch how the branches of individual neurons grew and shrank over time. It turns out that determining which of the branches will grow follows an age-old axiom: The squeaky neuron gets the grease. “Louder neurons drown out their quieter neighbors,?Smith sa...Speak up: Louder neurons form more connections
...us video cameras on the fish’s developing brain to watch how the branches of individual neurons grew and shrank over time. It turns out that determining which of the branches will grow follows an age-old axiom: The squeaky neuron gets the grease. “Louder neurons drown out their quieter neighbors,?Smith sa...Mosaic mouse technique offers a powerful new tool to study diseases and genetics
... these cells in a live animal, you can potentially watch the tumor grow." Luo points out that MADM is more precise than the widely used "knockout mouse" technique, in which a gene of interest is removed ("knocked out") of every cell in the animal's body. The knockout method can have unwanted, deleterious ...Study finds adult stem cells can replicate
...pe." Animal models of inflammation let scientists watch all stages of the inflammatory process and allowed them to see how important neutrophils are to the early stages of that process. In the new study, Pham and her colleagues showed that cathepsin G is secreted by neutrophils, binds to the cells' surfa...Enzyme's newly discovered role may make it target for arthritis treatment
...pe." Animal models of inflammation let scientists watch all stages of the inflammatory process and allowed them to see how important neutrophils are to the early stages of that process. In the new study, Pham and her colleagues showed that cathepsin G is secreted by neutrophils, binds to the cells' surfa...Scientists use manufacturing methods to reconstruct mastodon
...sitors can peek through special viewing windows to watch preparators assemble the skeleton, which will bear 7-foot tusks. The specimen, named the Buesching mastodon for the Indiana family on whose property it was discovered in 1998, will join the museum's female mastodon skeleton, which has been on display...50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel
...s, "cells control these actions as carefully as we watch our finances, which is why so many of the most potent mediations we use to care for our patients' target one or another ion channel." Goldstein's team discovered the type of ion channel known as background (or leak) potassium channels in yeast cells...First real-time view of developing neurons reveals surprises, say Stanford researchers
...t after using new technology for the first time to watch these cells develop, a team of researchers at the ...ome fancy microscopy, the researchers were able to watch individual neurons as they matured in real time. The pair specifically monitored hundreds of neuron...UCLA scientists transform HIV into cancer-seeking missile
... mouse's tail and used a special optical camera to watch the carrier's movement. "The virus traveled through the animal's bloodstream and homed straight to the cancer cells in the lungs, where the melanoma had migrated," said Chen. When the researchers held the mouse under the camera, the luciferase illu...Nano-Probes Allow an Inside Look at Cell Nuclei
... in its infancy, but biologists may soon use it to watch the inner workings of a living cell like never bef...different quantum dots in two different cells, and watch as the cells exchange their mitochondria," says Chen, adding that their technique paves the way for ......—cohorts of humpback singers moving coherently?and watch the collective migration of species over large portions of an ocean basin. “So if I am a whale off Newfoundland, I can hear a whale off Bermuda,?says Clark. Singing whales appear to slalom from one geographic feature to the next using the echoes of t...The transparent organism: EMBLEM and Carl Zeiss give labs a unique look at life
...ds from studying single molecules - now we need to watch complex, three-dimensional processes in whole, living organisms. SPIM allows us to do that with unprecedented quality." In a series of technical innovations, Stelzer and his colleagues (in particular Jim Swoger and Jan Huisken) have made it possible...