Weizmann Institute scientists develop a general 'control switch' for protein activity
... the activity level, while in others this activity was reduced. Says Prof. Liscovitch: “We were surprised by the effectiveness of the method – it turns out that a small set of engineered proteins is needed to find the ones that respond to the drug. With their greater resources, biotechnology companies wi...UI anthropologist, colleagues discover remains of earliest giant panda
...s ago. The ancestor of today's giant panda really was a pygmy giant panda, says Russell Ciochon, UI prof...own as Ailuropoda microta, or "pygmy giant panda") was probably about three feet in length, compared to the modern giant panda, which averages in excess of...Researchers discover 'acquired' DNA key to certain bacterial infection
... said the researchers learned the genetic “island” was acquired from another bacterium because of its unique nucleotide structure, which differs from its Mycobacterium cousins. Such evolution likely took place over thousands of years, he pointed out, and may have come from a pathogen which also has the a...Reconstructing the biology of extinct species: A new approach
...e stable. The basic hypothesis of the project was that the organ of balance -- which helps stabilize an animal's gaze and coordinate its movements as it travels through the environment -- should be irrevocably linked to the type of locomotion produced by its limbs. "If an animal evolves a new way o...How 'memory' T cells curb the spread of viruses throughout the body
...de in lymphoid organs such as the lymph nodes. It was thought that to protect from disease, memory CD8 T...the lymph nodes to the site of viral entry. “It was very difficult to imagine how the memory T cells could win this race,” said Sigal, the lead author o...Human genetic 'deserts' are teeming with significant life
...hed sequence of the human genome announced in 2003 was a great achievement, it left a number of questions unanswered. Before the information contained in the sequence can be used to its best effect, the identity and precise location of all the protein-encoding and non protein-encoding genes in the geno...Restricting hospital-based services during SARS outbreak had modest impact
...at were imposed when a provincial health emergency was declared during the 2003 SARS (Severe Acute Respiratory Syndrome) outbreak in Toronto, Ontario, resulted in only modest reductions in overall admissions. In this study, Dr. Michael J. Schull and colleagues determined that restrictions on the non-urge...Children of smokers have more than 5 times higher levels of a nicotine toxin
...sease in Childhood. Having a mother that smokes was found to have the biggest independent effect on co... with increased amounts of cotinine. Cotinine was measured in 100 urine samples taken from infants aged 12 weeks. Seventy one of the babies had at lea...Prey not hard-wired to fear predators
...s come at a time when, after more than $23 million was spent to re-establish wolves in the northern Rocky Mountains, the animals are to be down-listed from federal protection. The states of Wyoming and Idaho have already proposed plans that would allow for as much as 85 percent of these once-protected w...3-D ultrasound scanner provides in-depth view of the brain
...ogy, which is currently available online. The work was supported by the National Institutes of Health. Brain surgeons now rely primarily on two-dimensional images produced by MRI or ultrasound, said Edward Light, a research and development engineer in the biomedical engineering department at Duke. "Th...Surprising origin of cell's internal highways
...Kaverina. However, conclusively demonstrating this was impossible before the advent of live-cell imaging techniques that could reveal the true origins of these structures. "The Golgi apparatus is very close to the centrosome," said Kaverina. "So if you're not looking at it precisely, it is hard to di...The mouflons of the Kerguelen archipelago
...a type of wild sheep). A pair of Corsican mouflons was imported from the Vincennes Zoo in Paris. Initially, the mouflon population grew exponentially, and then, from the early 1980s, it fluctuated between 300 and 700 individuals. The history of a fascinating research project Denis Réale discovere...Turn-ons and turn-offs for neurons
...of genes for example in cognition in the mouse, as was shown in key studies from 1996. But in spite of the published success, others scientists report some difficulties: in some experiments the full reactivation of Tet-regulated genes failed. Mazahir T. Hasan and colleagues at the Max Planck Institute fo...Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state
...pes of stem cells, the strategy used in this study was unique. Rather than simply searching for any genes... the researchers looked for genes whose expression was also correlated with the master stem cell regulator gene Oct4. They also applied very rigorous analy...Male circumcision overstated as prevention tool against AIDS
... their population. When this artificial weighting was removed Talbott found that circumcision was no longer statistically significant in explaining the variance in AIDS infection rates across the co...Gene therapy study shows safety and statistically significant improvement in Parkinson's disease
... symptoms on both sides of the body, the procedure was performed on only one side of the brain, enabling ...advanced Parkinson’s disease. The Phase 1 study was not specifically designed to assess efficacy. Nonetheless, the researchers reported the clinical out...Ancient retrovirus sheds light on modern pandemic
...g of the chimpanzee genome. "When the chimp genome was sequenced, a team of scientists at the University ...erence overall between the chimp and human genomes was the presence or absence of PtERV1," Emerman said. "Chimps have 130 copies of PtERV1 and humans have ...Scientists close in on missing carbon sink
...uptake from vertical profiles of atmospheric CO2," was written by an international team of scientists led...gate various aspects of the carbon cycle, but this was the first time that a team of scientists analyzed them to obtain a picture of sources and sinks of c...Ice Age extinction claimed highly carnivorous Alaskan wolves
...er in fact than their modern counterpart—but there was no overlap with modern wolves. This was unexpected. “We thought possibly they would be related to Asian wolves instead of American wolve......eted since a comprehensive program against smoking was launched in 2002, according to findings issued tod... and Mortality Weekly Report (MMWR). The 2006 rate was nearly 20% lower than the 2002 rate -- a decline that represents 240,000 fewer smokers. The City’s r...