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Tag: "want" at biology news

Weighting cancer drugs to make them hit tumors harder

...the weight higher or lower depending upon where we want the drug to concentrate." Even drugs with vastly elevated molecular weights � 2 million molecular weight -- achieved better concentrations in tumors than a lower molecular weight, the study showed. Chilkoti said chemotherapy by itself is small en...

Fish on acid: Hagfish cope with high levels of CO2

...nly poorly regulate their pH. The scientists next want to find the mechanisms by which they do this, and if prolonged exposure to high levels of CO2 causes any long term effects. ...

Radiotherapy advance points way to noninvasive brain cancer treatment

...he uptake mechanism is," she says. "But first, you want to know that it works and that it really has potential for saving lives." Because of the deadly nature of GBM, De Stasio says an alternative is desperately needed to current therapies that offer little promise for extending life. De Stasio says it w...

Research tracks whales by listening to sounds

... the summer. The Gulf of Alaska is not a place you want to be in the winter. But apparently, sperm whales don't mind." Other researchers participating in the study include Sue Moore, NOAA's Alaska Fisheries Center in Seattle; Kathleen M. Stafford, an OSU graduate now at the University of Washington; and ...

Secrets of the sea yield stronger artificial bone

...nlimited number of material combinations. "People want a strong, light, and porous material, which is almost a contradiction in terms, but nature does it," says Tomsia. "Bone is made from calcium phosphate and collagen, which are both extremely weak. But nature mixes them together at room temperature and...

New method for identifying microbes

...y. "Elucidating this complexity is essential if we want to fully understand the roles microbes play in global cycles, make use of their enormous metabolic capabilities, or easily identify potential threats to human health." Growing cultures of microbes to identify species is slow and error prone as the c...

Loosen leash on cancer protein 'watchdog,' researchers say

...u with two potentially unappealing choices: Do you want to die early of cancer or die early from wearing your body out?" The scientists theorized that the solution could lie with another protein the body produces naturally to keep p53 in check. This other protein, called Mdm2, keeps p53 inactive until it...

Scientists identify molecular structure of key viral protein

...es its work and then it's finished, spent. And you want the protein to be triggered at the right time and in the right place for fusion: when the virus binds to the cell's surface." The research team determined the pre-fusion structure by imaging crystals of the protein, using the extremely brilliant X-...

Researchers discover way to transport environmental arsenic to plant leaves in new clean-up strategy

... mechanism for sequestering arsenic in roots. "We want a 35- to 50-fold increase in these plants' ability to sequester arsenic," said Meagher, "and now that we understand the mechanism, we believe that is possible." Indeed, it appears possible to create arsenic-eaters among tree, shrub and even grass spe...

AIDS drug from sunflowers

... Together with the Jülich Research Centre they now want to attempt to manufacture the substance on a large...e is therefore currently ?,000 per milligram. 'We want to attempt to cultivate sunflower cells or other plant cells in a nutrient solution together with th...

Relationship of brain and skull more than just packaging

...hat, from a medical point of view, the researchers want to find genetic mechanism underlying craniosynostosis so that the problem can be prevented or cured. From an evolutionary point of view, researchers focus on the developmental basis for the physical change observed in the fossil record and propose hy...

Molecular mechanism may explain how fevers spark seizures

...to count how many are there at any time, but if we want to know where they all came from and where they're all going, that's a whole different problem." The team's discovery that high temperature reduces cell surface GABA-A receptor levels "raises the idea that one could develop a treatment for vulnerab...

Measuring artery repair cells could become new heart disease test

... low levels of EPCs would be those patients we may want to treat more aggressively." ALDH is produced in high amounts by stem cells in the bone marrow as part of the process of maintaining the longer lifespans of these cells. Researchers have used ALDH assays to measure the number of stem cells in the bo...

UC Riverside psychologist explores human perception, finds 'wow factor'

... get people ready for a test and tell them what we want them to do, and a lot of them think there's absolutely no way they'll be able to do that," said Rosenblum, whose field is perceptual psychology. "Some are very surprised when it turns out that they can." Rosenblum has given test subjects quite a few...

Biologists visualize protein interaction that may initiate viral infection

...College of Science. "Ultimately, researchers might want to find ways to treat or prevent viral infections, but in order to do that we first have to learn how viruses work and how they initiate infection." The findings are detailed in a research paper to appear on Feb. 10 in the journal Cell. The research...

How can we protect patients with weakened immune systems from influenza?

...roportions and supplies of vaccine are limited. We want to offer protection to these special populations of immunocompromised patients, but not to vaccinate them needlessly." Patients on chemotherapy, on immunosuppressive drugs, or with diseases that weaken the immune system may be especially vulnerable ...

When good DNA goes bad

...g and can exist in the genome, the scientists next want to understand why cells can sometimes process the ...thout creating double-stranded breaks. They also want to know why certain places in the genome become "hot spots" for these breaks, while other seemingly ...

USC, Rice to develop bacteria-powered fuel cells

...ne variable will affect the other two, and what we want to do is find out how to tweak each one to optimize the performance of the whole system." Lüttge's participation in the program grew out of a decade-long collaboration with principal investigator Kenneth Nealson, USC's Wrigley Chair in Environmental...

Findings advance use of adult stem cells for replacement bone

... medical school in the fall. "One of the reasons I want to become a surgeon is so I can help bring cutting-edge work from the laboratory into clinical practice." Datta said one of the main reasons she chose to attend Rice was because of the tremendous opportunities available through Rice's Century Schola...

Tool developed to silence genes in specific tissues using RNAi

...at provides expression specific to the tissue they want to target. "There are whole batteries of different promoters, ones specifically for skin, or different parts of the brain, or whatever organ or tissue you are likely to want," Wilkinson says. "By swapping out either of these modules, you have the pot...

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